Eine neue Lesetafel* zur gleichzeitigen Bestimmung von Lesevisus und Lesegeschwindigkeit

Radner, Wolfgang; Willinger, Ulrike; Obermayer, Wilfried; Mudrich, Claudia; Velikay-Parel, Michaela; Eisenwort, Brigitte

doi:10.1055/s-2008-1034969

Cited by 177 publications

(138 citation statements)

References 1 publication

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“…The regular scheduled follow-up visit included the following: a protocol refraction BCVA measurement according to ETDRS 10 reading performance using the Radner test 15,16 ophthalmoscopic examination colour fundus photography autofluorescence measurement fluorescein (FA) and indocyanine green (ICG) angiography fixation testing and fundus-controlled microperimetry In short, fundus autofluorescence was measured with the Heidelberg retina angiograph (HRA II, Heidelberg Engineering GmbH, Dossenheim, Germany). To exclude influence of image brightness on autofluorescence measurements, grey-scale values of the patch area were compared with autofluorescence in a pristine area outside the patch within the same eye.…”

Section: Patient Follow-upmentioning

confidence: 99%

Autologous translocation of the choroid and RPE in age-related macular degeneration: 1-year follow-up in 30 patients and recommendations for patient selection

Heussen

Fawzy

Joeres

et al. 2007

Eye

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Aim To evaluate the long-term (1 year) functional and anatomical outcome of autologous translocation of peripheral choroid and retinal pigment epithelium (RPE) in 30 patients with age-related macular degeneration (AMD). Methods After the extraction of the neovascular complex, an autologous peripheral full-thickness graft of RPE and choroid was positioned under the macula. Functional tests included ETDRS vision, reading (Radner test), and microperimetry (scanning laser ophthalmoscope). Fluorescein, indocyanine green angiography, and autofluorescence were monitored.

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Section: Patient Follow-upmentioning

confidence: 99%

Autologous translocation of the choroid and RPE in age-related macular degeneration: 1-year follow-up in 30 patients and recommendations for patient selection

Heussen

Fawzy

Joeres

et al. 2007

Eye

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“…As baseline characteristics, secondary outcome measures such as sex, age, cardiovascular risk factors, cataract grade (LOCS-III charts) [37], retinal fluorescein angiography (FLA), OCT scans, distance acuity (ETDRS charts), near acuity (Radner charts) [38], contrast sensitivity (Pelli-Robson charts), and patient’s subjective visual function (VF-14 questionnaires) [39] were assessed in all patients. CDGAS as primary outcome measure was determined by digitized color fundus photographs.…”

Section: Methodsmentioning

confidence: 99%

Monitoring of Drusen and Geographic Atrophy Area Size after Cataract Surgery Using the MD3RI Tool for Computer-Aided Contour Drawing

Brunner

Mora²,

Fonseca³

et al. 2012

Ophthalmologica

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Background/Aims: To monitor possible changes in the cumulated drusen or geographic atrophy area size (CDGAS) of nonexudative age-related macular degeneration (AMD) in patients before and after cataract surgery, using a new tool for computer-aided image quantification. Methods: Randomized, prospective, clinical trial. 54 patients with cataract and nonexudative AMD were randomly assigned into an early surgery group (ES = 28) and a control group (CO = 26) with a 6-month delay of surgery. CDGAS was determined with the MD3RI tool for contour drawing in a central region of digitized fundus photographs, measuring 3,000 µm in diameter. To evaluate CDGAS progression, differences in pixels and square millimeters were calculated by equivalent tests. Results: Forty-nine patients completed the visits over the 12-month period (ES = 27 and CO = 22). Mean pixel values increased from 201.5 (11.33 × 10^–3 mm²) to 202.7 (11.39 × 10^–3 mm²) in the ES group and from 191.6 (10.77 × 10^–3 mm²) to 194.6 (10.94 × 10^–3 mm²) in the CO group. Finally, equivalence of CDGAS differences between ES and CO could be demonstrated. No exudative AMD was recorded during the study period. Conclusion: In our cohorts, no significant changes were found in CDGAS 12 months after cataract surgery. The MD3RI software could serve as an efficient, precise and objective tool for AMD quantification and monitoring in future trials.

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“…The reading performance is evaluated using the Radner Reading charts for a testing distance of 25 cm. 5 Reading acuity was expressed as in logRAD. The MNREAD acuity chart were used in the trial site, Liverpool, the testing distance was 40 cm.…”

Section: Primary and Secondary End Pointsmentioning

confidence: 99%

Surgical management of subfoveal choroidal neovascular membranes in age-related macular degeneration by macular relocation: experiences of an early-stopped randomised clinical trial (MARAN Study)

Joussen

Wong

Walter

et al. 2009

Eye

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Rationale The MARAN (Macular Relocation in Age-related Neovascular disease) trial was planned to assess the effectiveness of full macular relocation (MR) in patients with neovascular age-related macular degeneration (AMD). Design Randomised, prospective, controlled clinical trial. Methods Patients suffering from visual loss because of AMD were randomised to either surgery or a control group receiving standard treatment (observation or photodynamic therapy (PDT)). The primary end point was the change of visual acuity (VA) (ETDRS) 52 weeks after randomisation compared with initial VA, and secondary end points included reading performance, contrast sensitivity, stability of fixation, eye-specific quality of life, and the absolute number of letters read correctly at 52 weeks compared with initial examination. Results Owing to early determination, only 28 patients were included in the study. The study did not show a difference between the two groups with respect to the final visual result or any of the secondary outcomes measured. The study was limited by the low recruitment that was, at least in part, attributed to the inherent risks for those patients randomised to the surgical arm of the study as well as to the emerging new treatments for AMD. Conclusion The results of the MARAN trial failed to recruit a sufficient number of patients and a superiority of surgery over observation or PDT in patients with exudative AMD was not shown. There was a trend that the reading function was superior after surgery. In the light of the new pharmacological treatments, surgical options such as MR will be an option for only selected cases.

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Eine neue Lesetafel* zur gleichzeitigen Bestimmung von Lesevisus und Lesegeschwindigkeit

Cited by 177 publications

References 1 publication

Autologous translocation of the choroid and RPE in age-related macular degeneration: 1-year follow-up in 30 patients and recommendations for patient selection

Autologous translocation of the choroid and RPE in age-related macular degeneration: 1-year follow-up in 30 patients and recommendations for patient selection

Monitoring of Drusen and Geographic Atrophy Area Size after Cataract Surgery Using the MD3RI Tool for Computer-Aided Contour Drawing

Surgical management of subfoveal choroidal neovascular membranes in age-related macular degeneration by macular relocation: experiences of an early-stopped randomised clinical trial (MARAN Study)

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