“…However, the RK Ia indubitably compares favorably with any mixed ventilation system (room class Ib), i.e., physically, a significantly higher reduction rate of germ and particles loads (OR field, tables of instruments) has been proven [ 23 ], [ 24 ], [ 25 ], [ 26 ], [ 27 ], [ 28 ], [ 29 ], [ 30 ], [ 31 ], [ 32 ], [ 33 ], [ 34 ]. Therefore, from the perspective of prevention, an RK Ia OR is generally recommended for all operations that have the highest requirements for very low germ rates (e.g., implantation of large endoprotheses in the fields of orthopedics/trauma surgery).…”