Latin America has suffered for many years deep economic, political, and social problems that have led to high levels of unemployment. Therefore, microentrepreneurship has been a way out of these precarious economic systems. This research presents an interpretative hermeneutic analysis of the meaning of work for microentrepreneurs in the metropolitan region of Lima, Peru. The qualitative naturalistic methodology was used and data were obtained through 24 interviews with microentrepreneurs according to inclusion criteria such as: located in the metropolitan region of Lima (divided into 4 regions: A, B, C, and D), more than 5 years of experience, more than 25 years of age, university level of study and having had a formal job. The data were processed through ATLAS.ti9, which allowed us to analyze the discourses of the microentrepreneurs. The main findings show the following emerging categories: Motivation for entrepreneurship, Advantages of self-employment, relationship with stakeholders or interest groups, and family involvement in the business. It is concluded that Latin American microentrepreneurs associate entrepreneurship as an opportunity to improve their quality of life and establish relationships with stakeholders, with the family playing a key role in the success or failure of the business.