El impacto psicosocial de la psoriasis

Serum prolactin levels in psoriasis and correlation with cutaneous disease activity

“…Furthermore, bromocriptine, a dopamine agonist that suppresses the secretion of PRL, has been used in the treatment of plaque‐type psoriasis and psoriatic arthritis with very good response 20,22,23 . Emotional disturbances are one of the most important causes of hyperprolactinaemia, 24 and stress is significantly associated with exacerbations of psoriasis, 6 thus secondary hyperprolactinaemia due to stress cannot be excluded. Nevertheless, we believe that the findings described above indicate that PRL may play a role in the pathogenesis of psoriasis.…”

“…It has been estimated that the human leucocyte antigen‐associated allele PSORS1 on chromosome 6 accounts for 30–50% of the genetic contribution of psoriasis, 4 especially in the Spanish population 5 . In addition to the genetic influences, some environmental factors, such as injury, infection, stress 6 drugs or hormonal disturbances, are necessary for development of the psoriatic phenotype.…”

Defining well-being in psoriasis: A Delphi consensus among healthcare professionals and patients

“…Panellists agreed that family support/friendships, social relationships, leisure/recreational activities, and work/activity were components of the social dimension. Previous studies indicate that psoriasis negatively impacts social interaction skills, making it challenging to make new friends, avoiding social engagements or modifying how one dresses 56 . In addition, it also affects work productivity, which is directly correlated with the severity of the disease 10 .…”