The work is devoted to investigate the interaction between the special rotational deformation and interface collinear cracks in nanocrystalline bi-materials. As an illustrative example, the effect of the disclination quadrupole produced by the special rotational deformation on the emission of lattice dislocation from a finite interfacial crack tip in nanocrystalline bi-material is explored theoretically using the complex variable method. The complex form expression of dislocation force and the critical stress intensity factors for the first edge dislocation emission under remote mode I loadings and mode II loadings are deduced. And the influences of material properties, grain size, disclination strength, disclination location and orientation, special rotational deformation orientations, and crack length on the critical stress intensity factors are discussed in detail. The results show that the special rotational deformation and the relative shear modulus of the upper the lower half plane have great effect on the lattice dislocation emission from the interface collinear crack tip.