Elastolytic Actinic Giant Cell Granuloma

Gutiérrez‐González, Enrique; Pereiro, Manuel; Toribio, Jaime

doi:10.1016/j.det.2015.03.002

Cited by 37 publications

(42 citation statements)

References 81 publications

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“…A single plaque remains in situ for months or even years until spontaneous remission occurs . As well as lesions on the skin, lesions on the conjunctiva have also been described . In addition, repigmentation of grey hairs in lesions of AEGCG, due to changes in the dermal environment, has been reported…”

Section: Discussionmentioning

confidence: 99%

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Multiple asymptomatic annular plaques on the scalp

Ürün¹,

Ürün²,

Erdogan

et al. 2019

Clin Exp Dermatol

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Section: Discussionmentioning

confidence: 99%

“…AEGCG has rarely been reported to be associated with diabetes mellitus, malignancy, temporal arteritis, sarcoidosis, X‐linked dominant protoporphyria, ischaemic stroke and alcoholic cirrhosis. Prior burn injuries are occasionally associated …”

Section: Discussionmentioning

confidence: 99%

Multiple asymptomatic annular plaques on the scalp

Ürün¹,

Ürün²,

Erdogan

et al. 2019

Clin Exp Dermatol

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“…EGCG, also known as annular EGCG or actinic granuloma, is an uncommon non-infectious granulomatous skin disorder, affecting predominantly middle-aged woman. It is characterised by an isolated or a low number of medium-sized to large (up to 10 cm) annular plaques, with a raised erythematous border and an atrophic hypopigmented centre, arising in chronically sun-exposed skin 1. The sites of predilection are the face, neck, upper trunk, forearms and dorsum of the hands.…”

Section: Discussionmentioning

confidence: 99%

Generalised papular variant of elastolytic giant cell granuloma

et al. 2019

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Elastolytic giant cell granuloma (EGCG), also known as actinic granuloma, is an uncommon granulomatous dermatosis usually characterised by asymptomatic annular plaques on sun-exposed skin. Its aetiology is not fully elucidated, but actinic damage has been considered the main causal factor. Atypical variants with lesions in a non-photodistributed pattern are rare and often related to a systemic disorder, suggesting a more complex pathogenesis and demanding for a screening work-up. Herein, we report a case of an adult obese, diabetic woman presenting with a generalised pruritic papular eruption, histologically revealing an elastolytic giant cell granuloma, with a good response to treatment. In this case, the dermatosis was probably associated with her metabolic comorbidities.

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“…The etiology is unknown and treatment is empirical. Spontaneous remission can occur [7-10], and consistent results have not been obtained with any treatments [11]. Previously reported effective therapies for AEGCG include topical and intralesional steroid [12,13], oral antimalarials, such as quinacrine [14], chloroquine [3], and hydroxychloroquine [15][16][17][18], clofazimine [19], topical pimecrolimus [20], tarcrolimus, [4,21] oral retinoid acid derivatives like isotretinoin [22] and acitretin [23][24], dapsone [25], fumaric acid [26], cyclosporine [27,28], and minocycline [29].…”

Section: Discussionmentioning

confidence: 99%