Electric field-induced changes in membrane proteins charge movement currents

Pulsed electric field processing preserves the antiproliferative activity of the milk fat globule membrane on colon carcinoma cells

“…Electroporation induced by PEF is ascribed to electric charge polarization (Zim-mermann et al, 1974). The combined action of moderate heat and PEF may have led to charge alterations causing structural changes leading to aggregation of β-LG (Bromley et al, 2005;Chen and Wu, 2006).…”

Hepatic “split lesion” in a fatal electrocution case

“…It usually occurs in combination with extensive electric burns of the overlying abdominal wall [15,16]. Less often encountered are haemorrhagic necrosis of the pancreas or gall bladder [5]. The location and extent of tissue damage depend on the field strength, frequency, duration of contact and tissue properties.…”

“…Most cases of electrocutions are from AC, while the only cases of electrocution from DC occur as a result of lightning strikes [6,17,18]. Alternating current in fact, tends to produce involuntary continuous spasm of the adjacent muscles at the point of entry, prolonging the duration of contact with the conductor and thus the amount of current flowing through the body [5,6,18].…”

“…Medical literature typically categorizes electrocution according to the level of applied voltage: low voltage (less than 1000 V) and high voltage (greater than 1000 V); as reported from medical-legal practice, 14-40% of mortal electrocution are caused by high-voltage injuries [3,4]. It is well known that an electrical shock may cause death or any degree of damage to various organs and systems; the severity of electric shock injury is dependent upon many variables: type of current, level of applied voltage, duration of shock, body contact surface area, resistance of tissue involved, contact with water or metal conductor and current pathway through the body [5].…”

Development of AC microelectrophoresis for rapid protein affinity evaluation

“…Thus, extensive studies have been done for the usage of electrophoresis. Recent noteworthy achievements include high-resolution capillary isoelectric focusing [4], automated liquid phase separation techniques [5,6], packed capillary column liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry [7], single-cell electroporation studies [8][9][10], protein dynamic property studies [11][12][13], and protein adsorption and transport studies [8,14]. In spite of its wide usage, electrophoresis still has a few problems.…”