Due to their narrow reflection peak as well as their compact structure, Guided Mode Resonance Filters (GMRFs) are attractive for many applications. We demonstrate the possibility to modulate the properties of a GMRF by associating it with liquid crystals (LCs). By impregnating the diffraction grating with LCs, it is possible to switch between an active and an inactive state depending on the polarization of the light or the applied voltage. In this paper we fabricated and characterized the first diffraction order of LCimpregnated gratings with different periods (0,8 to 5,0µm) and depths (130 to 840nm) to test the ability of liquid crystals to adjust the diffraction properties. Finally, around 99.8% of diffraction intensity turns off with a 90° rotation polarization at zero voltage and 90 to 99% by applying a voltage of 30V according to the grating dimensions. The effect of the grating dimension on the diffraction modulation capacity are discussed.