Electrochemical Behavior of Dopamine at a Penicillamine Self‐Assembled Gold Electrode and its Analytical Application

Abstract

The fabrication and electrochemical characteristics of penicillamine (PCA) self-assembled monolayer modified gold electrode were investigated. The self-assembled electrode shows an obvious electrocatalytic activity for the oxidation of dopamine (DA). In phosphate buffer (pH 7.0), the peak current is proportional to the concentration of DA in the range of 8.0 x 10(-6) approximately 1.0 x 10(-3) M by the cyclic voltammetry methods with the detection limits of 4.5 x 10(-7) M. The PCA self-assembled monolayer modified gold electrode can be applied to the determination of DA in practical injection samples with simplicity, rapidness, and accurate results.

A comparative study of the electrochemical characteristics and simultaneous determination of dopamine, acetaminophen, and aspirin at a ruthenium oxide nanoparticles modified glassy carbon electrode versus a bare one

“…So far, different modified electrodes have been used for the electrochemical determination of DA. [5][6][7][8][9][10] ASA, known as aspirin, is one of the most important antiinflammatory, antipyretic, antioxidant, and analgesic drugs in the world. 11,12 This drug is used to treat headaches, muscular pain, colds, respiratory diseases, and rheumatoid arthritis.…”

On the pH dependence of electroactivity of poly(methylene blue) films

“…Methylene blue (MB) chemically modified electrodes (CMEs) offer well recognized advantages in electroanalysis, especially in situations where the target analyte requires high overpotential [1,2]. In general, the characteristics of chemically modified electrodes arises from the advantageous combination of conventional electrochemical techniques with the chemical, structural and other specific properties of the modifying layer(s) [3,4]. Basically, the electrode surface modification can improve the electrochemical signal by mediating or catalyzing the charge transfer reaction [5], protecting the surface against passivation [6] and/or changing the course of the electrochemical mechanism [7,8].…”

Direct Voltammetric Determination of Dobutamine in Pharmaceutical Samples Using Multiwall Carbon Nanotubes Paste Electrode

“…Also, from the slope the value of transfer coefficient was calculated as α = 0.79 (assuming n = 2). 22 Tafel plots were obtained from raising part of the current voltage curve at scan rate 100 mV s -1 (Fig. 2).…”