Electrochemical Behavior of Herbal Antitumor Drug Aloe‐Emodin at Carbon‐Coated Nickel Magnetic Nanoparticles Modified Glassy Carbon Electrode

Abstract

The electrochemical behavior of aloe-emodin (AE), an important herbal antitumor drug, was investigated at a carbon-coated nickel magnetic nanoparticles modified glassy carbon electrode (CNN/GCE). A couple of well-defined redox peaks was obtained. Some electrochemical parameters of AE at a CNN/GCE, such as the charge number, exchange current density, standard heterogeneous rate constant, were measured. The square wave voltammetry (SWV) response of AE was linear with the concentration over two concentration intervals viz. 6.24 10 À9 À1.13 10 À6 M and 1.13 10 À6 À1.23 10 À5 M, with a detection limit of 2.08 nM. A fast, simple and sensitive detection and analysis of AE was developed.