Electrochemical behaviors and electrochemical determination of carbamazepine at ionic liquid modified carbon paste electrode in the presence of sodium dodecyl sulfate

Abstract

The electrochemical behavior and electrochemical determination of carbamazepine (CBZ) at hydrophobic ionic liquid 1-Benzyl-3-Methylimidazole hexafluorophosphate ([BnMIM]PF6) modified carbon paste electrode ([BnMIM]PF6/CPE) in the presence of sodium dodecyl sulfate (SDS) were investigated. A well-defined and sensitive oxidation peak was observed at [BnMIM]PF6/CPE in the presence of SDS and 0.10 M phosphate buffer solution (pH 6.80). The oxidation peak current of CBZ increased significantly at [BnMIM]PF6/CPE in the presence of SDS compared with that in the absence of SDS at carbon paste electrode. It suggested that both SDS and [BnMIM]PF6/CPE show an obvious enhancing effect on the electrochemical oxidation of CBZ. The electrochemical kinetic parameters for CBZ at [BnMIM]PF6/CPE in aqueous SDS solutions were also determined by Chronocoulometry and Chronoamperometry. Finally, the experimental conditions were optimized, and a new electrochemical method of determination for CBZ had been established. The oxidation peak current was linearly dependent on CBZ concentration in the range of 7.0 μM to 0.7 mM with a detection limit of 0.98 μM (signal to noice ratio, S/N = 3). The relative standard deviation for six determinations of 0.10 mM CBZ was between 1.40 and 2.13%. The proposed method was applied in the determination of CBZ in commercial tablet samples

Electrochemical Behaviors of Methocarbamol at an Acetylene Black-Ionic Liquid Modified Carbon Paste Electrode and its Electrochemical Determination

“…As continuations of our previous work, [25][26][27][28] an AB-[BnMIM]PF 6 /CPE had been fabricated by using acetylene black (AB) and 1-Benzyl-3-Methylimidazole hexafluorophosphate ([BnMIM]PF 6 ) as a modifier and characterized by both cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The electrochemical behaviors and the electrochemical determination of MET were investigated at the bare CPE, AB/CPE, [BnMIM]PF 6 /CPE and AB-[BnMIM]PF 6 /CPE by CV and the square wave voltammetry (SWV).…”

Electrochemical behavior of labetalol at an ionic liquid modified carbon paste electrode and its electrochemical determination

“…As continuations of previous work, [12][13][14][15] an IL/CPE was fabricated using 1benzyl-3-methylimidazole hexafluorophosphate ([BnMIM]PF 6 ) as a modifier and characterized by both cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The electrochemical behaviors and the electrochemical determination of LBT were investigated at both bare a CPE and [BnMIM]PF 6 /CPE by CV and the square wave voltammetry (SWV).…”

Electroanalysis of Benazepril Hydrochloride Antihypertensive Drug Using an Ionic Liquid Crystal Modified Carbon Paste Electrode

“…Ionic liquid modified carbon electrodes show some advantages over traditional CPEs, such as high conductivity and sensitivity, fast electron transfer and good antifouling ability for electroanalysis. Also carbon ionic liquid electrodes (CILEs) show good electrocatalytic activities and used as probes in several applications as in electrochemistry [18], gas and liquid chromatography [19], mass spectrometry [20], capillary electrophoresis [21] and sensors [22][23][24][25][26][27][28][29]. The electrochemical behavior of electroactive molecules, such as clozapine, adenine, guanine, nitrite, dopamine, ascorbic acid and DNA had also been investigated using IL modified electrodes [30][31][32][33][34][35].…”