Electrochemical C–H Alkylation of Azauracils Using <i>N</i>-(Acyloxy)phthalimides

Dash, Rupashri; Panda, Satya Prakash; Bhati, Kuldeep Singh; Sharma, Siddharth; Murarka, Sandip

doi:10.1021/acs.orglett.4c02662

Org. Lett.

2024

DOI: 10.1021/acs.orglett.4c02662

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Electrochemical C–H Alkylation of Azauracils Using N-(Acyloxy)phthalimides

Rupashri Dash,

Satya Prakash Panda,

Kuldeep Singh Bhati

et al.

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Electrochemically Induced, Metal Free Synthesis of 2‐substituted chroman‐4‐ones

Monirialamdari,

Podlaska,

Pomikło

et al. 2024

ChemistryOpen

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Electrochemically induced, decarboxylative functionalization of chromone‐3‐carboxylic acids by N‐hydroxyphthalimide esters as alkyl radical precursors was studied. Electrochemical protocol offers a sustainable and green approach, obviating the need for catalysts, relying on the direct reduction of NHPI esters using electric current. Developed protocol provides a straightforward route to the synthesis of diverse molecules with potential biological activity.

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Electrochemically Induced, Metal Free Synthesis of 2‐substituted chroman‐4‐ones

Monirialamdari,

Podlaska,

Pomikło

et al. 2024

ChemistryOpen

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Electricity-driven reductive coupling reaction of imines with N-(acyloxy)phthalimides

Liu,

Feng

2024

Tetrahedron Letters

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Electrochemical C–H Alkylation of Azauracils Using N-(Acyloxy)phthalimides

Cited by 2 publications

References 47 publications

Electrochemically Induced, Metal Free Synthesis of 2‐substituted chroman‐4‐ones

Electrochemically Induced, Metal Free Synthesis of 2‐substituted chroman‐4‐ones

Electricity-driven reductive coupling reaction of imines with N-(acyloxy)phthalimides

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