2015
DOI: 10.1007/s10856-015-5545-9
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Electrochemical characterization and in-vitro bio-assessment of AZ31B and AZ91E alloys as biodegradable implant materials

Abstract: The degradation of magnesium alloys, AZ31B and AZ91E, are under review due to a their ability to degrade under physiological conditions and successively yield an oxidized biocompatible by-product which can safely be absorbed by the body. By exploiting the biodegradability of magnesium alloys, the prospects of developing an unprecedented class of implant are at hand. To do so however, the rate of corrosion of the alloys must be modified in order to better suit physiological conditions. Therefore, anodization wa… Show more

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Cited by 19 publications
(11 citation statements)
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“…The reason for improved corrosion resistance is the formation of an insoluble Al 2 O 3 layer, instead of Mg(OH) 2 , which is soluble in chloride solution . Recent studies have proved the enhanced corrosion resistance of Mg–Al alloys as compared to pure Mg in simulated body fluids (SBFs), in phosphate buffer saline (PBS), and sodium chloride (NaCl) solutions . Figure represents the comparative Tafel plots of pure Mg and three Mg–Al alloys, and results exhibit the improvement in the corrosion potential of all the three Mg–Al alloys as compared to pure Mg.…”
Section: Mg and Its Alloysmentioning
confidence: 99%
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“…The reason for improved corrosion resistance is the formation of an insoluble Al 2 O 3 layer, instead of Mg(OH) 2 , which is soluble in chloride solution . Recent studies have proved the enhanced corrosion resistance of Mg–Al alloys as compared to pure Mg in simulated body fluids (SBFs), in phosphate buffer saline (PBS), and sodium chloride (NaCl) solutions . Figure represents the comparative Tafel plots of pure Mg and three Mg–Al alloys, and results exhibit the improvement in the corrosion potential of all the three Mg–Al alloys as compared to pure Mg.…”
Section: Mg and Its Alloysmentioning
confidence: 99%
“…A recent in vivo study of Mg–1.0Al alloy in a rat for 4 weeks showed good biocompatibility of these alloys . Similarly, short‐term biocompatibility of Mg–Al alloys has been proven, but long‐term biocompatibility needs detailed in vivo studies. Moreover, the safe content limit of Al in the Mg–Al alloys should be defined by more in vivo studies.…”
Section: Mg and Its Alloysmentioning
confidence: 99%
“…Исследование жизнеспособности клеток при их культивировании на поверхности имплантируемых материалов в условиях in vitro -ши роко распространенный метод доклинической оценки биосовместимости материалов. Среди наиболее распространенных тестов: оценка морфологии клеток при помощи флуоресцентной и сканирующей электронной микроскопии, а также биохимические тесты МТТ, ХТТ и MTS [1,2,11,17]. Кроме того, тесты in vitro легко выполняются, хорошо поддаются стандартизации и могут проводиться многократно.…”
Section: исследование биосовместимости титановых имплантатовunclassified
“…Кроме того, тесты in vitro легко выполняются, хорошо поддаются стандартизации и могут проводиться многократно. В настоящем исследовании проводили сравнительный анализ биосовместимости in vitro образцов имплантатов из титанового сплава ВТ 1-0, обработанного тремя различными способами (три группы) с использованием культуры клеток мышиных фибробластов линии Balb/NIH 3 Т3 (ПанЭко, РФ) [17].…”
Section: исследование биосовместимости титановых имплантатовunclassified
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