Electrochemical characterization of tenoxicam using a bare carbon paste electrode under stagnant and forced convection conditions

Guzmán-Hernández, Dafne Sarahia; Ramı́rez-Silva, Maria Teresa; Palomar-Pardavé, M.; Corona-Avendaño, S.; Galano, Annia; Rojas-Hernándéz, Alberto; Romero-Romo, M.

doi:10.1016/j.electacta.2011.10.046

Cited by 14 publications

(7 citation statements)

References 17 publications

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“…Guzmán-Hernández et al [21], that the electrochemical oxidation of Tenox is irreversible, see also Guzmán-Hernández et al [8,13], and that the oxidation potential diminishes with increasing pH: the same occurred with the current associated to this peak. From the Tenox s Pourbaix diagram, see Fig.…”

Section: Global Equilibrium Logbmentioning

confidence: 70%

See 1 more Smart Citation

Spectrophotometric and electrochemical quantification of the host–guest interaction of tenoxicam and β-CD in aqueous solution at different pH values

Guzmán-Hernández

Ramı́rez-Silva

Rojas-Hernándéz

et al. 2015

Journal of Electroanalytical Chemistry

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Section: Global Equilibrium Logbmentioning

confidence: 70%

“…The electrochemical study of the interaction between the b-CD and the Tenox was carried out through cyclic voltammetry, CV, keeping track of the oxidation peak's current [8,13] as a function of the b-CD concentration [5], at different pHs, namely 0.420, 3.175 and 7.150.…”

Section: Electrochemical Studymentioning

confidence: 99%

Spectrophotometric and electrochemical quantification of the host–guest interaction of tenoxicam and β-CD in aqueous solution at different pH values

Guzmán-Hernández

Ramı́rez-Silva

Rojas-Hernándéz

et al. 2015

Journal of Electroanalytical Chemistry

Self Cite

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“…It shows a strong inhibitory effect in vitro on human metalloproteinase (stromelysin and collagenase) enzymes that stimulate cartilage destruction. 1 In the literature, high performance liquid chromatography, [2][3][4][5][6][7] thin layer chromatography, 8 flow injection spectrophotometric analysis, [9][10][11] and spectrophotometric and spectrofluorimetric methods [12][13][14][15] are reported as methods for the determination of TX in pharmaceuticals and biological samples. These methods require mostly time-consuming sample preparation procedures such as extraction and the costly instrumentation makes their usage inconvenient.…”

Section: Introductionmentioning

confidence: 99%

Electroanalytical Determination of the Antiinflammatory Drug Tenoxicam in Pharmaceutical Dosage Forms

Ağın

Atal

2019

tjps

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Non-steroidal antienflamatuvar ilaç etken maddesi tenoksikamın (TX) elektro-oksidasyon davranışı çok duvarlı karbon nanotüple (MWCNT) modifiye edilmiş camsı karbon elektrot (GCE) ile dönüşümlü voltametri, diferansiyel puls voltametri (DPV) ve kare dalga voltametri (SWV) ile çalışılmıştır. Gereç ve Yöntemler: GCE, TX'in voltametrik metodlarla hassas tayini için MWCNT ile modifiye edilmiştir. Bulgular: Potansiyel pozitif yönde tarandığında TX'in pik akımı 0.520 V civarında DPV ile, 0.570 V civarında SWV ile oluşmuştur. TX'in oksidasyon prosesi tersinmez ve diffüzyon kontrollü davranış göstermiştir. DPV ve SWV için doğrusal cevaplar sırasıyla 2×10-7-1×10-5 M, 1.43×10-9 M yakalama alt sınırı (LOD) ile, 8×10-9-8×10-6 M, 9.97×10-10 M LOD ile 1 M asetat tamponu pH 5.5 içinde elde edilmiştir. Sonuç: Tamamen valide edilmiş DPV ve SWV başarılı bir şekilde TX'in farmasötik dozaj formundan miktar tayini için uygulanmış ve memnun edici sonuçlar elde edilmiştir.

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“…It indicates strong inhibitory effect in vitro on human metalloproteinase (stromelysin and collagenase) enzymes that stimulate cartilage destruction. 1 In literature, high performance liquid chromatography (HPLC), [2][3][4][5][6][7] thin layer chromatography (TLC), 8 flow injection spectrophotometric analysis, [9][10][11] spectrophotometric and spectrofluorimetric methods [12][13][14][15] are reported as the methods for determination of TX in pharmaceuticals and biological samples. These methods require mostly time-consuming sample preparation procedures such as extraction and costly instrumentation makes their usage inconvenient.…”

Section: Introductionmentioning

confidence: 99%

Electroanalytical Determination of Antiinflammatory Drug Tenoxicam in Pharmaceutical Dosage Forms

Ağın¹,

Atal²

2018

tjps

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The electro-oxidation behavior of nonsteroidal anti-inflammatory drug tenoxicam (TX) was studied on multiwalled carbon nanotubes (MWCNTs) modified glassy carbon electrode (GCE) by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and square wave voltammetry (SWV). GCE was modified with MWCNTs for sensitive determination of TX with voltammetric methods. The current peaks for TX occurred at around 0.520 V for DPV and 0.570 V for SWV when the potential was scanned in the positive direction. The oxidation process of TX has shown irreversible and diffusion controlled behavior. The linear responses have been obtained in the range from 2 × 10 -7 to 1 × 10 -5 M with the limit of detection (LOD)1.43 × 10 -9 for DPV and from 8 × 10 -9 to 8 × 10 -6 with the LOD 9.97 × 10 -10 for SWV in 1 M acetate buffer solution at pH 5.5. Fully validated DPV and SWV were successfully applied for the determination of TX from pharmaceutical dosage form and obtained satisfying results. Özet: Nonsteroidal antienflamatuvar ilaç etken maddesi tenoksikamın (TX) elektrooksidasyon davranışı çok duvarlı karbon nanotüple (MWCNTs) modifiye edilmiş camsı karbon elektrot (GCE) ile dönüşümlü voltametri (CV), diferansiyel puls voltametri (DPV) ve kare dalga voltametri (SWV) ile çalışıldı. Camsı karbon elektrot, TX'in voltametrik metodlarla hassas tayini için MWCNTs ile modifiye edildi. Potansiyel pozitif yönde tarandığında TX'in pik akımı 0.520 V civarinda DPV ile, 0.570 V civarında SWV ile oluştu. TX'in oksidasyon prosesi tersinmez ve difüzyon kontrollü davranış gösterdi. DPV ve SWV için doğrusal cevaplar sırasıyla 2 × 10 -7 -1 × 10 -5 M, 1.43 × 10 -9 M yakalama alt sınırı (YAS) ile, 8 × 10 -9 -8 × 10 -6 M, 9.97 × 10 -10 M YAS ile 1 M asetat tamponu pH 5.5 içinde elde edildi. Tamamen valide edilmiş DPV ve SWV başarılı bir şekilde TX'in farmasötik dozaj formundan miktar tayini için uygulandı ve memnun edici sonuçlar elde edildi.

show abstract

Electrochemical characterization of tenoxicam using a bare carbon paste electrode under stagnant and forced convection conditions

Cited by 14 publications

References 17 publications

Spectrophotometric and electrochemical quantification of the host–guest interaction of tenoxicam and β-CD in aqueous solution at different pH values

Spectrophotometric and electrochemical quantification of the host–guest interaction of tenoxicam and β-CD in aqueous solution at different pH values

Electroanalytical Determination of the Antiinflammatory Drug Tenoxicam in Pharmaceutical Dosage Forms

Electroanalytical Determination of Antiinflammatory Drug Tenoxicam in Pharmaceutical Dosage Forms

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