Electrochemical detection of folic acid using a modified screen printed electrode

Abstract

In this work, an electrochemical sensor was established for the detection of folic acid based on Ni-BTC (BTC = benzene-1,3,5-tricarboxylic acid) metal-organic framework (MOF) modified screen-printed electrode (SPE). Electrochemical techniques (cyclic voltammetry (CV), differential pulse voltammetry (DPV), linear sweep voltammetry (LSV) and chrono­ampere­metry (CHA) were used for the detection of folic acid at Ni-BTC MOF modified SPE. The results indicate that the as-prepared sensor has a good electrocatalytic effect on the detection of folic acid. This electrochemical sensor showed a dynamic linear response range from 0.08 to 635.0 µM and the detection limit was estimated to be 0.03±0.001 µM. Moreover, the feasibility of Ni-BTC MOF/SPE sensor to detect folic acid in real samples was also evaluated by the standard addition method.

Electrochemical sensing of B-complex vitamins: current challenges and future prospects with microfluidic integration

“…In addition, the conventional addition method was used to assess the viability of the Ni-BTC MOF/SPE sensor's ability to detect B9 in real samples. 74 Abid et al suggested a 2-D MoS 2 nanosheet with applied gold nanoparticles at the SPCE (AuNPs-MoS 2 /SPCE)-based electrochemical sensor for detecting vitamin B9. The AuNPs-MoS 2 / SPCE sensor showed a good sensitivity of 20.636 mA mM −1 cm −2 , in the linear concentration range of 0-20 mM with an LOD of 1.04 mM.…”

“…In addition, the conventional addition method was used to assess the viability of the Ni–BTC MOF/SPE sensor's ability to detect B9 in real samples. 74 …”

Voltammetric determination of hydrochlorothiazide at a modified carbon paste electrode with polypyrrole nanotubes

“…The chemical modification of inert substrate electrodes offers significant advantages in the design and development of electrochemical sensors. The properties of chemically modified electrodes that have driven their development include increased selectivity and sensitivity, chemical and electrochemical stability, larger usable potential windows, and resistance to fouling [23][24][25][26][27][28][29][30][31][32][33][34][35]. The incorporation of nanomaterials has had a great impact on the development of electrochemical sensors [36][37][38][39][40].…”

An electrochemical sensing platform based on a modified carbon paste electrode with graphene/Co3O4 nanocomposite for sensitive propranolol determination

“…The chemical modification of inert substrate electrodes offers significant advantages in the design and development of electrochemical sensors [48][49][50][51][52]. In operations, the redox-active sites often shuttle electrons between a solution of the analyte and the substrate electrodes, with a significant reduction of the activation overpotential [53][54][55]. A further advantage of chemically modified electrodes is that they are less prone to surface fouling and oxide formation compared to inert substrate electrodes [56][57][58][59][60].…”