Electrochemical detection of the synthetic cathinone 3,4-methylenedioxypyrovalerone using carbon screen-printed electrodes: A fast, simple and sensitive screening method for forensic samples

Lima, Camila D.; Couto, Rosa A. S.; Arantes, Luciano José; Marinho, Pablo Alves; Pimentel, Dilton M.; Quinaz, M. Beatriz; Silva, Rodrigo A. B. da; Richter, Eduardo M.; Barbosa, Sandro L.; Santos, Wallans Torres Pio dos

doi:10.1016/j.electacta.2020.136728

Cited by 36 publications

(12 citation statements)

References 32 publications

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“…These electrodes were also used for mephedrone analysis [43,44]. Mephedrone had already been detected using electrochemical methods [43][44][45][46][47][48][49].…”

Section: Introductionmentioning

confidence: 99%

Development of an Electrochemical Sensor Using a Modified Carbon Paste Electrode with Silver Nanoparticles Capped with Saffron for Monitoring Mephedrone

Papaioannou

Karastogianni

Girousi

2022

Sensors

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Mephedrone, also known as 4-methylmethcathinone, is growing into a prominent recreational drug for young people. When it came to detecting mephedrone, limited efforts were made using electrochemical sensors. As a result, this application depicts the fabrication of a new, sensitive, selective, and economical electrochemical sensor capable of detecting mephedrone by using silver nanoparticles capped with saffron produced through electropolymerization to modify carbon paste electrodes (CPEs). Silver nanoparticles (AgNPs) were capped with saffron (AgNPs@Sa) using a green method. AgNPs@Sa were studied using electron scanning microscopy (SEM) and UV-vis spectroscopy. The sensor was evaluated under the optimum condition to determine its analytical features. The results showed that this procedure had a wide linear range, low detection limit and sufficient reproducibility. Furthermore, the sensor posed sufficient stability. Moreover, it was applied in the determination of mephedrone in urine samples, showing the potential applicability of this electrochemical sensor in real sample analysis.

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“…These electrodes were also used for mephedrone analysis [43,44]. Mephedrone had already been detected using electrochemical methods [43][44][45][46][47][48][49].…”

Section: Introductionmentioning

confidence: 99%

Development of an Electrochemical Sensor Using a Modified Carbon Paste Electrode with Silver Nanoparticles Capped with Saffron for Monitoring Mephedrone

Papaioannou

Karastogianni

Girousi

2022

Sensors

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“…Additionally, MDPV signal disappears following the extraction step, indicating the effectiveness of such process. Indeed, the electrochemical mechanism of MDPV oxidation at a carbon surface has been recently proposed [ 60 ]. After incubating the sensor with MDPV, its anodic wave is again observed, confirming the adequate access of this molecule to the sensor surface through the previously formed cavities.…”

Section: Resultsmentioning

confidence: 99%

3,4-Methylenedioxypyrovalerone (MDPV) Sensing Based on Electropolymerized Molecularly Imprinted Polymers on Silver Nanoparticles and Carboxylated Multi-Walled Carbon Nanotubes

et al. 2021

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3,4-methylenedioxypyrovalerone (MDPV) is a harmful and controlled synthetic cathinone used as a psychostimulant drug and as sport-enhancing substance. A sensor was developed for the direct analysis of MDPV by transducing its oxidation signal by means of an electropolymerized molecularly imprinted polymer (e-MIP) built in-situ on the screen-printed carbon electrode’s (SPCE) surface previously covered with multi-walled carbon nanotubes (MWCNTs) and silver nanoparticles (AgNPs). Benzene-1,2-diamine was used as the functional monomer while the analyte was used as the template monomer. Each step of the sensor’s development was studied by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) in a solution containing ferricyanide, however no redox probe was required for the actual MDPV measurements. The interaction between the poly(o-phenylenediamine) imprinted polymer and MDPV was studied by density-functional theory (DFT) methods. The SPCE-MWCNT-AgNP-MIP sensor responded adequately to the variation of MDPV concentration. It was shown that AgNPs enhanced the electrochemical signal by around a 3-fold factor. Making use of square-wave voltammetry (SWV) the developed sensor provided a limit of detection (LOD) of 1.8 μmol L–1. The analytical performance of the proposed sensor paves the way to the development of a portable device for MDPV on-site sensing to be applied in forensic and doping analysis.

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“…The coin had different compositions; currently it's composed of steel while copper is used for its electroplating [31]. The developed protocol was validated by analysis of the street sample for both of these synthetic cathinones that indicates a good economic approach which was useful as an electrochemical detection tool for NPS analysis LOD and good stability [35]. The proposed method played a vital role in forensic analysis of MDPV in seized samples.…”

Section: Synthetic Cathinonesmentioning

confidence: 99%

Voltammetric Analysis of New Psychoactive Substances

Patil

Pandey

2021

AJFSFM

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New Psychoactive Substances (NPS) are synthetic drugs that create similar effects as various narcotic drugs and psychotropic substances. Different NPS such as mephedrone, synthacaine, synthetic cannabinoids, etc. are available today which are sold across numerous platforms like drug markets, head shops, the dark web, etc. They are emerging rapidly and becoming popular in society because of their variable nature and ease in avoiding breaking the law. Consequently, their analysis is extremely crucial in the prohibition of drug abuse and the development of laboratory methods. This review introduces a broad overview of the analysis of various new psychoactive substances by voltammetric techniques such as cyclic voltammetry, differential pulse voltammetry, square wave voltammetry, stripping voltammetry etc. It also focuses on various methodologies that were developed for the detection of these NPS which play a leading role in forensic investigation by providing a rapid, sensitive, and cost-effective platform of analysis. The need for the advancement of various detection methods and analysis of more drugs is additionally discussed.

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Electrochemical detection of the synthetic cathinone 3,4-methylenedioxypyrovalerone using carbon screen-printed electrodes: A fast, simple and sensitive screening method for forensic samples

Cited by 36 publications

References 32 publications

Development of an Electrochemical Sensor Using a Modified Carbon Paste Electrode with Silver Nanoparticles Capped with Saffron for Monitoring Mephedrone

Development of an Electrochemical Sensor Using a Modified Carbon Paste Electrode with Silver Nanoparticles Capped with Saffron for Monitoring Mephedrone

3,4-Methylenedioxypyrovalerone (MDPV) Sensing Based on Electropolymerized Molecularly Imprinted Polymers on Silver Nanoparticles and Carboxylated Multi-Walled Carbon Nanotubes

Voltammetric Analysis of New Psychoactive Substances

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