Electrochemical Glutathione Sensor Based on Electrochemically Deposited Poly‐m‐aminophenol

Abstract

Preparation and characterization of electrodes suitable for determination of glutathione is reported in this study. For this poly-m-aminophenol (PmAP), poly-o-aminophenol, and poly-p-aminophenol were electrochemically deposited from aqueous solution on the surface of glassy carbon (GC) electrode by potential cycling in the range of + 0.2-+ 1.0 V. The modified GC electrodes were characterized by cyclic voltammetry, electrochemical impedance spectroscopy, contact angle measurement and ellipsometry. It was found that poly-m-aminophenol modified GC electrode (PmAP/GC-electrode) is most suitable for electroanalytical determination of glutathione. An electroanalytical system for the determination of glutathione based on the PmAP/GC-electrode was developed. The analytical system was characterized by low limit of detection, good stability, high sensitivity and wide linear detection range.

Electrocatalytic oxidation of NADH based on polyluminol and functionalized multi-walled carbon nanotubes

“…some authors devoted in electrochemical glutathione sensor based on electrochemically deposited poly-m-aminophenol. 7 The electrochemical oxidation of nicotinamide adenine dinucleotide (NADH) has received considerable interest due to its very important role as a cofactor in a whole diversity of dehydrogenase-based bioelectrochemical devices such as biosensors, biofuel cells, and bioreactors. [8][9][10] However, direct oxidation of NADH at a conventional solid electrode is highly irreversible, requires a large activation energy, and proceeds with coupled side reactions, poisoning the electrode surface.…”

A highly sensitive persulfate sensor based on a hybrid nanocomposite with silicomolybdate doping poly(3,4-ethylenedioxythiophene) on multi-walled carbon nanotubes

“…some authors devoted in electrochemical glutathione sensor based on electrochemically deposited poly-m-aminophenol and poly(brilliant cresyl blue). 28,29 Among the conducting polymers, poly (3,4-ethylendioxythiophene), PEDOT, is a very attractive material due to its low band gap, high conductivity and stability, and transparency in the doped state. [30][31][32] PEDOT has been proposed as an alternative to traditional polymers as the electroactive component in biosensors.…”

“…27 However, some of them 55 are not eco-friendly such as those using lead or dye composites. 28,29 Among the conducting polymers, poly (3,4-ethylendioxythiophene), PEDOT, is a very attractive material due to its low band gap, high conductivity and stability, and transparency in the doped state. some authors devoted in electrochemical glutathione sensor based on electrochemically deposited poly-m-60 aminophenol and poly(brilliant cresyl blue).…”

Electrochemical determination of glutathione based on an electrodeposited nickel oxide nanoparticles-modified glassy carbon electrode

“…9,10 However, these separation methods suffer from difficulties or drawbacks in terms of equipment cost, the need for derivatization, and sample preparation. 3 Electrochemiluminescence 11 and electrochemical detection 5,10,[12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] have also been demonstrated for the analysis of GSH. In contrast, electrochemical detection has the advantages of simplicity, high sensitivity, high selectivity, and low instrumental cost.…”