Electrochemical methods in understanding the redox processes of drugs and biomolecules and their sensing

Manna, Sudipa; Sharma, Abhishek; Satpati, Ashis Kumar

doi:10.1016/j.coelec.2021.100886

Cited by 12 publications

(15 citation statements)

References 52 publications

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“…The calculated values of the specific surface area corresponded to 0.0024 cm 2 and 0.1258 cm 2 for SPE and SPE/SWCNT, respectively. These results confirmed the good conductivity and electron transfer properties of carbon nanomaterials such as carbon nanotubes [14,[39][40][41][42]. SPEs modified with SWCNTs (SPE/SWCNTs) were used for the electrochemical registration of ASNase.…”

Section: Resultssupporting

confidence: 61%

“…Disposable screen-printed electrodes (SPEs) are widely used in electrochemical sensing of hemeproteins, drugs, DNA, drug-protein, and drug-DNA interactions [14,[39][40][41]. They possess commercial availability, low cost, and the ability to modify the working surface with a broad choice of chemical materials with different structures.…”

Section: Resultsmentioning

confidence: 99%

“…As shown earlier, Thr12, Tyr25, Thr89, Asp90, and Lys162 of ASNase participate in catalysis and substrate binding [29][30][31][32][33][34][35][36][37][38]. These amino acids are conserved for all bacterial asparaginases [29,[34][35][36][37][38][39][40][41][42]. The mechanism of catalysis involves two triads, Thr12-Lys162-Asp90, which resembles the classical serine proteinase mechanism and participates in catalysis, and Thr12-Tyr25-Glu283, which participates in substrate binding and releases products of catalytic reactions [35][36][37].…”

Section: Introductionmentioning

confidence: 95%

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Electroenzymatic Model System for the Determination of Catalytic Activity of Erwinia carotovora L-Asparaginase

et al. 2022

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An electrochemical method for the determination of the catalytic activity of L-asparaginase (ASNase) from Erwinia carotovora was proposed. Our approach is based on the electrooxidation of amino acids from L-asparaginase polypeptide backbones. The electrochemical behavior of ASNase on electrodes obtained by screen-printing modified with single-wall carbon nanotubes (SPE/SWCNTs) as sensing elements demonstrated a broad oxidation peak at 0.5–0.6 V centered at 0.531 ± 0.010 V. We have shown that in the presence of the substrate L-asparagine, the oxidation current of the enzyme was reduced in a concentration-dependent manner. The specificity of electrochemical analysis was confirmed in experiments with glycine, an amino acid with no substrate activity on ASNase and does not reduce the oxidation peak of L-asparaginase. The addition of glycine did not significantly influence the amplitude of the oxidation current. The innovative aspects of the proposed electrochemical sensor are the direct monitoring of ASNase catalytic activity and a reagentless approach, which does not require additional reagents or labels.

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Section: Resultssupporting

confidence: 61%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 95%

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Electroenzymatic Model System for the Determination of Catalytic Activity of Erwinia carotovora L-Asparaginase

et al. 2022

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Section: Figurementioning

confidence: 99%

“…[ 42 ] Each and every parameter involved in the electrochemical method with differential pulse voltammetry is shown in Figure 9 . [ 43 ]…”

Section: Synthesis Of Nanomaterialsmentioning

confidence: 99%

Future of Nanotechnology in Food Industry: Challenges in Processing, Packaging, and Food Safety

Singh¹,

Dutt

Sharma

et al. 2023

Global Challenges

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and methods. Nanoparticles are thought to be the smallest objects that may operate as a single entity, displaying novel behaviors and characteristics. [2] Since nanoparticles have a larger surface area and mass transfer rates than big particles (of the same composition), they seem to have higher biological and chemical activity, penetrability, catalytic behavior, enzymatic reactivity, and quantum characteristics. [3] The dimensions, construction, and properties of nanomaterials are used to classify them into several categories. Nanomaterials with a high surface-area-to-volume ratio (SA:V) have the potential to exhibit desirable physiochemical characteristics, including those related to diffusivity, solubility, color, thermodynamics, optics, and magnetization. [4] Nowadays, the food market is growing day by day. In 2023, the food market will generate $9.43 trillion in revenue. The market is expected to grow by 6.21% yearly. With a market volume of US$1.64 trillion in 2023, Confectionery & Snacks will be the market's largest sector. According to population estimates, US$1228.00 in income is expected per person in 2023. By 2023, internet sales in the food industry will account for 8.5% of total revenue. In 2023, it is estimated that the Food market would have a volume per person of 340.87 kg. Today, the market of food needs innovations that can make food that is easy to use, real, and delicious so that it can keep Over the course of the last several decades, nanotechnology has garnered a growing amount of attention as a potentially valuable technology that has significantly impacted the food industry. Nanotechnology helps in enhancing the properties of materials and structures that are used in various fields such as agriculture, food, pharmacy, and so on. Applications of nanotechnology in the food market have included the encapsulation and distribution of materials to specific locations, the improvement of flavor, the introduction of antibacterial nanoparticles into food, the betterment of prolonged storage, the detection of pollutants, enhanced storage facilities, locating, identifying, as well as consumer awareness. Labeling food goods with nano barcodes helps ensure their security and may also be used to track their distribution. This review article presents a discussion about current advances in nanotechnology along with its applications in the field of food-tech, food packaging, food security, enhancing life of food products, etc. A detailed description is provided about various synthesis routes of nanomaterials, that is, chemical, physical, and biological methods. Nanotechnology is a rapidly improving the field of food packaging and the future holds great opportunities for more enhancement via the development of new nanomaterials and nanosensors.

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A Mini Review on Electrochemical Nano-biosensors in Detection of Drugs/Pesticides

Raman,

Mishra,

Yadav

et al. 2024

Indian J Microbiol

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Electrochemical methods in understanding the redox processes of drugs and biomolecules and their sensing

Cited by 12 publications

References 52 publications

Electroenzymatic Model System for the Determination of Catalytic Activity of Erwinia carotovora L-Asparaginase

Electroenzymatic Model System for the Determination of Catalytic Activity of Erwinia carotovora L-Asparaginase

Future of Nanotechnology in Food Industry: Challenges in Processing, Packaging, and Food Safety

A Mini Review on Electrochemical Nano-biosensors in Detection of Drugs/Pesticides

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