Electrochemical Microarray for Identification Pathogens: A Review

Rodrigo, Miguel Ángel Merlos; Zítka, Ondřej; Krejčová, Ludmila; Hynek, David; Masařík, Michal; Kynický, Jindřích; Heger, Zbyněk; Adam, Vojtěch; Kizek, René

doi:10.1016/s1452-3981(23)08021-5

Cited by 6 publications

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Electrochemical Arrays for Bioassay Applications

Cortón

Mikkelsen

2016

Trends in Bioelectroanalysis

View full text Add to dashboard Cite

This chapter presents a survey of developments and bioassay applications of individually addressable electrochemical arrays covering the past two decades and including over 90 references. Many different array designs have been fabricated, from macroscopic devices that have two to four sensing elements to ultramicroelectrode arrays containing as many as 12,000 individually addressable micrometer-sized working electrodes. Some inexpensively fabricated arrays are intended for single sample analysis and are disposable, while others are encapsulated for incorporation into reusable microfluidic systems. Devices and assays are grouped according to the types of modifications done to the sensing elements, and sections are included to consider unmodified elements as well as modifications with enzymes, antibodies or antigens, nucleic acids, in addition to viable cells and tissues. Some trends have been identified, and possible future directions are suggested.

show abstract

Electrochemical Arrays for Bioassay Applications

Cortón

Mikkelsen

2016

Trends in Bioelectroanalysis

View full text Add to dashboard Cite

show abstract

Advanced nanotechnologies in avian influenza: Current status and future trends – A review

Moulick

Richtera

Milosavljević

et al. 2017

Analytica Chimica Acta

View full text Add to dashboard Cite

In the last decade, the control of avian influenza virus has experienced many difficulties, which have caused major global agricultural problems that have also led to public health consequences. Conventional biochemical methods are not sufficient to detect and control agricultural pathogens in the field due to the growing demand for food and subsidiary products; thus, studies aiming to develop potent alternatives to conventional biochemical methods are urgently needed. In this review, emerging detection systems, their applicability to diagnostics, and their therapeutic possibilities in view of nanotechnology are discussed. Nanotechnology-based sensors are used for rapid, sensitive and cost-effective diagnostics of agricultural pathogens. The application of different nanomaterials promotes interactions between these materials and the virus, which enables researchers to construct portable electroanalytical biosensing analyser that should effectively detect the influenza virus. The present review will provide insights into the guidelines for future experiments to develop better techniques to detect and control influenza viruses.

show abstract

Ultrasensitive detection of influenza viruses with a glycan-based impedimetric biosensor

Hushegyi

Pihíková

Bertók

et al. 2016

Biosensors and Bioelectronics

View full text Add to dashboard Cite

An ultrasensitive impedimetric glycan-based biosensor for reliable and selective detection of inactivated, but intact influenza viruses H3N2 was developed. Such glycan-based approach has a distinct advantage over antibody-based detection of influenza viruses since glycans are natural viral receptors with a possibility to selectively distinguish between potentially pathogenic influenza subtypes by the glycan-based biosensors. Build-up of the biosensor was carefully optimized with atomic force microscopy applied for visualization of the biosensor surface after binding of viruses with the topology of an individual viral particle H3N2 analyzed. The glycan biosensor could detect a glycan binding lectin with a limit of detection (LOD) of 5 aM. The biosensor was finally applied for analysis of influenza viruses H3N2 with LOD of 13 viral particles in 1 μl, what is the lowest LOD for analysis of influenza viral particles by the glycan-based device achieved so far. The biosensor could detect H3N2 viruses selectively with a sensitivity ratio of 30 over influenza viruses H7N7. The impedimetric biosensor presented here is the most sensitive glycan-based device for detection of influenza viruses and among the most sensitive antibody or aptamer based biosensor devices.

show abstract

Electrochemical Microarray for Identification Pathogens: A Review

Cited by 6 publications

References 36 publications

Electrochemical Arrays for Bioassay Applications

Electrochemical Arrays for Bioassay Applications

Advanced nanotechnologies in avian influenza: Current status and future trends – A review

Ultrasensitive detection of influenza viruses with a glycan-based impedimetric biosensor

Contact Info

Product

Resources

About