Electrochemical Oxidation of Dopamine in the Presence of Secondary Amine. An Alternative Way for Quantitative Dopamine Determination at a Gold Electrode

Łuczak, Teresa

doi:10.1002/elan.200804223

Cited by 30 publications

(20 citation statements)

References 60 publications

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“…Upon reversal of the potential, a cathodic peak, E p C , at 120 mV vs. SCE is observed, corresponding to the reduction of o-dopamine-quinone back to DA. This is consistent with the well-known quasi-reversible electrochemistry of DA [13]. Although the voltammograms recorded in the presence of the sulfonated ␤-CD have similar characteristics to that recorded in a pure DA solution, there are two significant differences.…”

Section: Evidence For the Formation Of An Inclusion Complexsupporting

confidence: 88%

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An electrochemical study in aqueous solutions on the binding of dopamine to a sulfonated cyclodextrin host

Hendy

Breslin

2012

Electrochimica Acta

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a b s t r a c tClear evidence for the formation of a weak inclusion complex between dopamine (DA) and a sulfonated ␤-CD host in aqueous solution was obtained using a combination of electrochemical approaches. Using cyclic voltammetry, a distinct increase in the oxidation potential of DA and a reduction in the peak oxidation current were observed on adding an excess concentration of the sulfonated ␤-CD to the electrolyte solution. Equally, a clear increase in the half-wave oxidation potential of DA was observed in the presence of the sulfonated ␤-CD using rotating disc voltammetry. The association constant, K, was computed as 331.3 ± 5.8, indicating the formation of a weak inclusion complex, while a 1:1 stoichiometry for the inclusion complex was deduced from a Job's plot analysis. The rate constant for the oxidation of DA was found to decrease on formation of the inclusion complex. This was attributed to higher reorganization energy for the oxidation of the included DA. These changes in the electrochemistry of DA were not observed when an excess of the smaller sulfonated ␣-CD was added to the electrolyte, indicating that these variations are not connected with simple electrostatic interactions between the protonated DA and the anionic sulfonated groups. It is proposed that the aromatic ring of the DA molecule includes within the cyclodextrin cavity, while the protonated amine group remains outside the cavity, bound electrostatically with the anionic sulfonated groups.

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Section: Evidence For the Formation Of An Inclusion Complexsupporting

confidence: 88%

“…DA is an interesting guest as it is protonated at near-netural pH, providing a positively charged guest molecule. In addition, dopamine is electroactive, being readily oxidized into the o-dopaminoquinone [13]. This means that the formation of the inclusion complex can be studied using electrochemical techniques.…”

Section: Introductionmentioning

confidence: 99%

An electrochemical study in aqueous solutions on the binding of dopamine to a sulfonated cyclodextrin host

Hendy

Breslin

2012

Electrochimica Acta

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“…The dependence of j p on c EP obtained on a bare gold electrode is linear in the range of 1 mM to 500 mM of epinephrine. This is in agreement with the results obtained earlier [30,40]. This concentration range is extended from 0.1 mM to 650 mM and to 750 mM when epinephrine is oxidized on 2D and 3D electrodes, respectively (Fig.…”

supporting

confidence: 93%

“…0.998, n ¼ 10) in the pH range from 2 to 10. These values are very close to the theoretical Nernstian value of 0.059 V [40] and consequently this point out that the electron transfer step is preceded by a protonation with the same number of protons involved in the epinephrine oxidation mechanism, regardless of the surface 2D or 3D used for electrode modifications.…”

supporting

confidence: 71%

Epinephrine Oxidation in the Presence of Interfering Molecules on Gold and Gold Electrodes modified with Gold Nanoparticles and Thiodipropionic Acid in Aqueous Solution. A Comparative Study

Łuczak

2009

Electroanalysis

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Thiodipropionoc acid (TDPA), cysteamine (CA) and gold nanoparticles (Au-NPs) modified gold pure electrodes have been applied in voltammetric sensors for simultaneous detection of epinephrine (EP), ascorbic (AA) and uric (UA) acids. Modified electrodes with self assembled layers (SAMs) show high selectivity, sensitivity, reproducibility and stability. A linear relationship between the epinephrine concentration and the current response is obtained in the range of 0.1 mM to 0.65 mM with the detection limit 0.065 mM for the electrodes modified at 2D surface and in the range of 0.1 mM to 0.75 mM with the detection limit 0.082 mM for the electrodes modified at the 3D surface.

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“…One of the possible explanations suggests the intramolecular cyclization of oxidized DA to dopaminochrome (Equation 3) and its involvement in the redox exchange [43]. It should be mentioned that the last step can be performed either electrochemically on an electrode surface or chemically with DA as a reducing agent and hydrogen ions source.…”

Section: Da Determinationmentioning

confidence: 99%

Dopamine Sensor Based on a Composite of Silver Nanoparticles Implemented in the Electroactive Matrix of Calixarenes

et al. 2011

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A sensitive electrochemical sensor based on a composite containing silver nanoparticles and a redox active thiacalixarene with catechol fragments in the substituents at the lower rim has been developed and used for dopamine detection. The electrochemical investigation of thiacalixarene in homogeneous solution and on the electrode interface showed the reversible character of the redox conversion of catechol fragments and its involvement in the chemical reduction of silver which resulted in formation of uniform nanoparticles of 4-6 nm in diameter. The use of such a material for electrode modification made it possible to record a high amplitude cathodic signal at À700 mV that was proportional to the dopamine concentration within 1 nM-1 mM. (limit of detection 0.5 nM).

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Electrochemical Oxidation of Dopamine in the Presence of Secondary Amine. An Alternative Way for Quantitative Dopamine Determination at a Gold Electrode

Cited by 30 publications

References 60 publications

An electrochemical study in aqueous solutions on the binding of dopamine to a sulfonated cyclodextrin host

An electrochemical study in aqueous solutions on the binding of dopamine to a sulfonated cyclodextrin host

Epinephrine Oxidation in the Presence of Interfering Molecules on Gold and Gold Electrodes modified with Gold Nanoparticles and Thiodipropionic Acid in Aqueous Solution. A Comparative Study

Dopamine Sensor Based on a Composite of Silver Nanoparticles Implemented in the Electroactive Matrix of Calixarenes

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