2014
DOI: 10.1007/s13246-014-0282-9
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Electrochemical performance of platinum electrodes within the multi-electrode spiral nerve cuff

Abstract: In this study, the electrochemical performance of platinum electrodes within a multi-electrode spiral cuff to be used for selective nerve stimulation was investigated. The original cuff, simplified into a half-cuff, contained a single row of nine electrodes (0.5 × 2 mm) at a distance of 2 mm from its inner surface. Cyclic voltammetry was used to investigate the electrochemical reactions at the electrode-electrolyte interface, to define a potential window within which the electrode could be safely used in selec… Show more

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Cited by 4 publications
(5 citation statements)
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“…The electrochemical potential range of biological implants is determined by the oxidation and reduction of water, commonly known as the “water window” . Determining the stable voltage range is essential information for in vitro performance and electrochemical characterization of the neural electrodes, whose role is to inject electrical charge into the neural tissue in a reversible manner and without inducing unwanted Faradaic reactions .…”
Section: Resultsmentioning
confidence: 99%
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“…The electrochemical potential range of biological implants is determined by the oxidation and reduction of water, commonly known as the “water window” . Determining the stable voltage range is essential information for in vitro performance and electrochemical characterization of the neural electrodes, whose role is to inject electrical charge into the neural tissue in a reversible manner and without inducing unwanted Faradaic reactions .…”
Section: Resultsmentioning
confidence: 99%
“…Electrochemical activation of EFG/PDMS electrodes involved application of a reduction potential of −1.6 V for 2 h, which resulted in increased capacitance of the electrodes (see section ) but also widening of the “water window” for the cathodic range from −0.4 V (cathodic limit for the EFG/PDMS before activation) to −1.3 V (cathodic limit for the EFG/PDMS after activation) (Figure S12b). A cathodic threshold voltage of −0.6 V was chosen for the platinum-based neural cuff, which was determined from the CV of a Pt electrode in PBS (Figure S3) and as used in the literature …”
Section: Resultsmentioning
confidence: 99%
“…The literature values for CSC c for Pt electrodes vary from 2.92 to 26.6 mC/cm 2 [43]. Cuff Pt electrodes were characterized as having CSC c = 4 mC/cm 2 and CIC = 75 µC/cm 2 (GSA = 1 mm 2 ) [22].…”
Section: Resultsmentioning
confidence: 99%
“…Difficulties are also encountered in calculating electrolyte (or excitable tissue) resistance in in vivo experiments where tissue resistivity is heterogeneous [29] and it changes after electrode implantation [32]. Furthermore, identifying the access voltage precisely was found to be a hard issue due to factors such as current-pulse rise times and stray capacitance [15,22,33].…”
Section: Methodsmentioning
confidence: 99%
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