Electrochemical preparation of chitosan/hydroxyapatite composite coatings on titanium substrates

Abstract

Composite coatings containing brushite (CaHPO4 · 2H2O) and chitosan were prepared by electrochemical deposition. The brushite/chitosan composites were converted to hydroxyapatite/chitosan composites in aqueous solutions of sodium hydroxide. The coatings ranged from ≈1 to 15% chitosan by weight. Qualitative assessment of the coatings showed adhesion significantly improved over that observed for electrodeposited coatings of pure HA. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res 66A: 411–416, 2003

Biocomposites and hybrid biomaterials based on calcium orthophosphates

“…Different methods for bringing these two components together into biocomposites have already been realized, including mechanical blending, compounding, ball milling, dispersion of ceramic fillers into a polymer-solvent solution, a melt extrusion of a ceramic/polymer powder mixture, coprecipitation and electrochemical co-deposition. 36,63,[297][298][299] Three methods for preparing a homogeneous blend of HA with PLLA were compared. 297 First, a dry process, consisting of mixing ceramic powder and polymer pellets before a compression molding step, was used.…”

“…Various biocomposites of calcium orthophosphates with chitosan 298,482,500,512,527,565,[645][646][647][648][649][650][651][652][653]674,675,690,695,799,807,[811][812][813][814][815][816][817][818][819][820][821][822][823][824][825][826][827][828] and chitin 232,476,612,[829][830][831][832][833] are also very popular. For example, a solutionbased method was developed to combine HA powders with chitin, in which the ceramic particles were uniformly dispersed.…”

Calcium orthophosphate-based biocomposites and hybrid biomaterials

“…Different ways have been already realized to bring these two components together into composites, like mechanical blending, ball milling, dispersion of ceramic fillers into a polymer-solvent solution, a melt extrusion of a ceramic/polymer powder mixture, coprecipitation, and electrochemical codeposition [32,59,[238][239][240]. Besides, there is an in situ formation, which involves either synthesizing the reinforcement inside a preformed matrix material or synthesizing the matrix material around the reinforcement [59,241].…”

Formation of hydroxyapatite coatings with addition of chitosan from aqueous solutions by thermal substrate method

“…But only few of them are acceptable for obtaining CS-HA coatings, because of high temperatures of processes and possibility of chitosan degradation. Among methods for HA-CS coating deposition are simple mixing and heating method [13], biomimetic method [14][15][16], low temperature wet chemical method [17], electrochemical deposition [18], electrochemistry assisted deposition [19,20], electrophoretic deposition [21,22]. In our work we proposed thermal substrate method [23,24] (TSM) for deposition of F HA-CS coatings onto Ti 6 Al 4 V substrates from aqueous solutions.…”