Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity

Abstract

South Africa is a country with a wide variety of plants that may contain excellent anti-tyrosinase inhibitors. With wide applications in cosmetics, pharmaceuticals and food products, tyrosinase inhibitors have received very special attention in the recent past as a way of preventing the overproduction of melanin in epidermal layers which often over time brings detrimental effects on human skin. In this present study, a fast screening method using a cyclic voltammetry technique was applied in the evaluation of methanolic extracts of twenty-five species of plants from the Lamiaceae family for anti-tyrosinase activity. Among these plants, those that showed a fast current inhibition rate at a minimum concentration when compared to a kojic acid standard were classified as having the greatest anti-tyrosinase activity. These include Salvia chamelaeagnea, S. dolomitica, Plectranthus ecklonii, P. namaensis, and P. zuluensis. The results presented herein focused in particular on providng firsthand information for further extensive research and exploration of natural product materials with anti-tyrosinase activity from South African flora for use in cosmetics, skin care and medicinal treatments.

Lamium Plants—A Comprehensive Review on Health Benefits and Biological Activities

“…The current study of Etsassala et al [146] applied a fast screening method using a cyclic voltammetry technique for evaluating anti-tyrosinase activity of twenty-five species of plants from the Lamiaceae family: among these, those that showed a fast current inhibition rate at a minimum concentration when compared to a kojic acid standard were classified as having the greatest anti-tyrosinase activity such as Salvia chamelaeagnea , S. dolomitica , Plectranthus ecklonii , P. namaensis , and P. zuluensis .…”

Plant Extracts as Skin Care and Therapeutic Agents

“…Sapindaceae roots [231] Lonicera japonica Caprifoliaceae whole plant [232] Mangifera caloneura Anacardiaceae leaves [195] Manilkara kauki Sapotaceae fruits, leaves, seeds, stem bark, woods [233] Matthiola incana Brassicacea leaves, flower buds [234] Melastoma normale Melastomacea roots [235] Momordica cochinchinensis Cucurbitacea fruits (pulp, aril, seed) [236] Monotheca buxifolia Sapotaceae leaves, stems [237] Nelumbo nucifera Nelumbonaceae whole flower, stamen [161] Onosma bourgaei, Boraginaceae aerial parts [238] Onosma trachytricha Paliurus spina-christi Rhamnaceae fruits, leaves, stems [239] Pistacia lentiscus Anacardiaceae leaves [240] Phaseolus vulgari Fabaceae seed coat [241] Phytolacca dioica Phytolaccacea fruits [242] Plectranthus ecklonii, P. namaensis, P. zuluensis Lamiacea aerial parts [243] Punica granatum Punicaceae seeds [169] Rheum palmatum Polygonacea roots, rhizomes [244] Rhizophora racemosa Rhizophoraceae leaves, stem bark [245] Rhizophora…”

Tyrosinase Inhibitory Activity of Garcinia latissima Miq. Extracts

“…Each sample was used a control without tyrosinase 20 . Blank was using DMSO and blank control without enzyme 21 . After 10 min incubation at 37°C, then absorbance was measured using a microplate reader at 490 nm, triplicate 22 .…”