Electrochemical Study of Iridium Oxide Coating on Stainless Steel Substrate

Kakooei, Saeid; Ismail, Mokhtar Che; Wahjoedi, Bambang Ari

doi:10.1016/s1452-3981(23)14390-2

Cited by 29 publications

(2 citation statements)

References 14 publications

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“…This value is in the range reported in the literature using different materials including stainless steel, Au, and Pt. 34,51…”

Section: Methodsmentioning

confidence: 99%

“…This value is in the range reported in the literature using different materials including stainless steel, Au, and Pt. 34,51 Before conducting potentiometric measurements, the orthopaedic-based sensor underwent treatment involving the application of a constant potential of 200 mV for 5 minutes. This treatment is needed to stabilize the composition of Ir 3+ / Ir 4+ on the electrode surface, thereby enhancing the analytical performances in terms of reproducibility and long-term stability.…”

Section: Orthopaedic-based Sensor Modificationmentioning

confidence: 99%

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Functionalized orthopaedic implant as pH electrochemical sensing tool for smart diagnosis of hardware infection

Fiore,

Mazzaracchio,

Gosti

et al. 2024

Analyst

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“…This value is in the range reported in the literature using different materials including stainless steel, Au, and Pt. 34,51…”

Section: Methodsmentioning

confidence: 99%

Section: Orthopaedic-based Sensor Modificationmentioning

confidence: 99%

Functionalized orthopaedic implant as pH electrochemical sensing tool for smart diagnosis of hardware infection

Fiore,

Mazzaracchio,

Gosti

et al. 2024

Analyst

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Self‐Propelled Tags for Protein Detection

Mayorga‐Martinez

Pumera

2019

Adv Funct Materials

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Protein detection is of tremendous significance for biological and biomedical sciences. Because there is no equivalent of polymerase chain reaction available as a tool for protein detection, researchers must rely on tags to enhance the limits of detection. One of the crucial steps is the actual labeling of proteins, which relies on diffusion of the label, which is very slow, or external mixing of the label and protein is needed. Here, a conceptually new approach is demonstrated: self-propelled tags that autonomously move in the solution and enhance protein detection. The tags used here are based on IrO 2 /Pt bilayer microtubules, which can self-propel and act as moving tags for enhanced protein electrochemical detection. This completely new label-based protein detection concept using selfpropelled tag will find a wide spectrum of applications.

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Multimodal Neural Probes with Small Form Factor Based on Dual‐Side Fabrication

Kim

Leong

et al. 2022

Adv Materials Technologies

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a specific region of the brain through various physical means, including electrical, chemical, optical, and acoustic, have been proposed to investigate neuronal circuits. [8][9][10][11][12] Furthermore, since neurons relay information to downstream neurons through either electrical or chemical synaptic transmission, real-time monitoring of neurotransmitters in the extracellular space of the brain offers additional insight to that observed from the electrophysiological activities. Thus, recently, multimodal neural probes that perform both electrical recording and neurotransmitter detection in the extracellular environment have also been proposed. [13][14][15] However, it is still a challenge to design a multimodal neural probe that detects both neurotransmitters and neural signals at a small form factor. For a multimodal neural probe, while a high-density neural recording and a high electrochemical sensitivity are preferred, a high channel count and sensitivity require a larger shank area. For example, the width of the probe scales linearly with the number of microelectrodes due to the signal lines. Similarly, for electrochemical detection, a larger working electrode (WE) on the shank is also required to achieve high sensitivity. Moreover, to achieve a reliable electrochemical analysis, two electrodes additional to the WE are required to form a three-electrode system. [16] However, because the shank dimension is directly related to the acute neural tissue damage during the insertion, it is important to design a shank with a small dimension. This clear trade-off between the probe dimension (i.e., tissue damage) and performance (i.e., channel counts and high sensitivity) is a major challenge in implementing a multimodal neural probe at a small form factor.To overcome this trade-off, several methods such as multilayer metal interconnect, [17] e-beam photolithography, [18] and dual-sided micropatterning [19,20] have been recently proposed to achieve high density without increasing the dimension of the polymer neural probes. Through these efforts, neural probe arrays with 16-channel SU-8, 32-channel polyimide (PI), and 64-channel Parylene-C (PC) shank have been reported using the standard monolithic microfabrication. [21][22][23][24] In the case of electrochemical analysis, a three-electrode system composed of working, reference, and counter electrodes (WE, RE, and CE) is often used. However, to prevent brain damage from the insertion of the third electrode, a two-electrode system is often Monitoring both individual neuronal spikes and neurotransmitters released from a specific brain region plays a significant role in understanding neuronal circuits and brain functionalities. While polymer neural probe offers distinctive advantages of flexibility, optical transparency, and biocompatibility, achieving high-density recording with multifunctionalities and multimodality is still a challenge due to limited microfabrication techniques. Here, a multimodal polymer neural probe array based on a dual-side fabrication process wit...

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Electrochemical Study of Iridium Oxide Coating on Stainless Steel Substrate

Cited by 29 publications

References 14 publications

Functionalized orthopaedic implant as pH electrochemical sensing tool for smart diagnosis of hardware infection

Functionalized orthopaedic implant as pH electrochemical sensing tool for smart diagnosis of hardware infection

Self‐Propelled Tags for Protein Detection

Multimodal Neural Probes with Small Form Factor Based on Dual‐Side Fabrication

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