“…For example, NaLS macromolecules exhibit oblate conformations and negatively charged surfaces, with tendencies of self-assembly and loosely aggregate in water [ [51] , [52] , [53] ]. Thus, NaLS not only triggers the formation and stabilization of AgNPs, but it could further protect them in either physico-chemical or biological aggressive environments, mediates their attachment/confinement on surfaces, tunes the release of silver ions, and allows the design of complex material, extending the applicative field [ [54] , [55] , [56] ]. In this regard, we have previously reported, probably for the first time, the use of NaLS for the reduction and stabilization of silver ions, in the absence of any additional process, as one of the simplest, facile, cost-efficient, and greener synthesis for obtaining stable and catalytically active AgNPs [ 56 , 57 ], which was later confirmed by works reported by other groups [ 58 , 59 ].…”