Electrochemistry of Nucleic Acids

DNA probe modified with 3-iron bis(dicarbollide) for electrochemical determination of DNA sequence of Avian Influenza Virus H5N1

“…One of them is the approach based on changes in electrochemical activity of nucleobases upon the hybridization events. This concept have been proposed by Palecek and co-workers (Palecek 2009;Palecek and Bartosik, 2012). The other idea is based on changes of electrochemical parameters of the interface: electrode/aqueous solution caused by hybridization reaction (Malecka et al, 2013;Zhang et al, 2008).…”

Carbon-based Electrode Materials for DNA Electroanalysis

“…14,18 This is because these techniques have such advantages as low cost, compact size, and ease of handling compared with the fluorescent method. Many DNA detection methodologies have been proposed over the last two decades.…”

“…2 Recently, new carbon materials, and in particular doped diamond, CNT, and graphene nanostructures, have been actively developed as sensing platforms for biomolecules, such as DNA and proteins. [6][7][8][9][10] In fact, with the development of many kinds of DNA analysis systems, 6,[11][12][13][14][15][16][17][18] the number of reports on DNA electroanalysis using the above-mentioned carbon material electrodes has been increasing rapidly throughout the world as shown in Fig. 2(a) 10,11,23,24 In fact, the number of publications related to DNA electroanalysis using both CNT and graphene material electrodes are increasing as shown in Fig.…”

An electrochemiluminescence biosensor for 8-oxo-7,8-dihydro-2′-deoxyguanosine quantification and DNA repair enzyme activity analysis using a novel bifunctional probe

“…Electrochemical sensors offer some distinctive advantages in terms of simplicity, low cost, fast response and miniaturization. Electrochemical detection of several DNA damage products has been studied extensively (Paleček and Fojta, 2001;Rusling et al, 2007;Paleček and Bartošík, 2012;Wu and Guo, 2014). In particular, voltammetric and electrochemiluminescence (ECL) sensors for the detection of 8-oxodGuo were developed by relying on the electrocatalytic reaction between Os(bpy) 2 Cl þ -polyvinylpyridine and 8-oxodGuo (Dennany et al, 2004;Mugweru et al, 2004).…”