Electrolyte Disturbances in Critically Ill Children Admitted to Paediatric Tertiary Care Centre

Paidy, Anirudh Reddy; Thapar, Col Rajeev Kumar; Gupta, Brig Rakesh Kumar

doi:10.14260/jemds/2017/708

Cited by 6 publications

(2 citation statements)

References 22 publications

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“…The most frequent electrolyte abnormalities are hyponatremia associated with central nervous system disorders (52.9%), gastrointestinal disorders (17.6%), and sepsis (11.8%) [ 7 , 20 ]. Moreover, malaria, gastroenteritis, pneumonia, malnutrition, neonatal sepsis [ 21 ], postsurgical status, prolonged PICU stay, fluid intake, and mechanical ventilation were other significantly associated factors [ 22 , 23 ].…”

Section: Introductionmentioning

confidence: 99%

Hyponatremia and its associated factors in children admitted to the pediatric intensive care unit in eastern Ethiopia: a cross-sectional study

Berhanu,

Yusuf,

Mohammed

et al. 2023

BMC Pediatr

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Background Hyponatremia is a serious problem that leads to substantial increases morbidity and mortality in critically ill children. The identification of risk factors, implementation of preventive measures, and timely diagnosis and management are crucial to reduce adverse events related to hyponatremia. Despite the higher burden of the problem in Ethiopia, evidence related to the risk factors for hyponatremia among children in Ethiopia is limited; in particular, no study has been identified in eastern Ethiopia. Therefore, we aimed to determine the magnitude of hyponatremia and its associated factors in children admitted to the pediatric intensive care unit at the Hiwot Fana Comprehensive Specialized University Hospital. Methods A facility-based cross-sectional study was conducted using 422 medical records of pediatric patients admitted to the pediatric intensive care unit at Hiwot Fana Comprehensive Specialized University Hospital from January 2019 to December 2022. Medical records were reviewed to collect data. Data were analyzed using a statistical package for social sciences (SPSS) version 26. A binary logistic regression model with an adjusted odds ratio (aOR) and a 95% confidence interval (CI) was used to identify factors associated with the outcome variable. Statistical significance was set at p < 0.05. Results The magnitude of hyponatremia was 39.1% (95% CL: 34.4–43.8%). The age of the child (aOR = 2.37;95% CL:1.31–4.31), diagnosis of sepsis (aOR = 2.33; 95% CL:1.41–3.84), surgical procedures (aOR = 2.39; 95% CL:1.26–4.56), nutritional status (aOR = 2.60; 95% CL:1.51–4.49), and length of hospital stay (aOR = 3.04; 95% CL: 1.73–5.33) were factors significantly associated with hyponatremia. Conclusions Four out of ten children admitted to pediatric intensive care units had hyponatremia. Hyponatremia was significantly associated with the age of the child, malnutrition, sepsis, surgical procedures, and length of hospital stay. To reduce the burden of hyponatremia and associated mortality, attention should be focused on improving the care of malnourished children, and those with sepsis, and the quality of postoperative monitoring services. Moreover, intervention strategies aimed at reducing the burden of hyponatremia should target the identified factors.

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Section: Introductionmentioning

confidence: 99%

Hyponatremia and its associated factors in children admitted to the pediatric intensive care unit in eastern Ethiopia: a cross-sectional study

Berhanu,

Yusuf,

Mohammed

et al. 2023

BMC Pediatr

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“…These imbalances also result in longer stay in hospitals [12], thus adding significantly to the costs of management. Therefore, to prevent a bad consequence, early detection and intervention to correct these imbalances are crucial [13]. Five possible mechanisms for the occurrence of electrolyte imbalance are the underlying disease process, end organ injury, fluid and electrolyte interventions, use of medications with potential of electrolyte derangements and application of critical care technology i.e.positive pressure ventilation [14].…”

Section: Introductionmentioning

confidence: 99%

Acid-Base Status & Electrolyte Imbalance in Critically ill Ventilated Infants

Akter,

Hossain,

Mamun

2023

Glob Acad J Med Sci

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Introduction: Children who are critically ill typically suffer from a disease process that impacts many organ systems. To improve the outcome, these children are treated in a pediatric intensive care unit. The primary focus of intensive care medicine is the care of patients who are facing immediate life-threatening conditions. The aim of this study was to determine the acid- base status & electrolyte imbalance in critically ill ventilated infants. Methods: This was a prospective observational study and was conducted in the Department of Intensive Care Unit (ICU) of Bangladesh Shishu Hospital & Institute, Dhaka, Bangladesh during the period from January 2020 to December 2020. In our study, we included 50 critically ill ventilated young infants in ICU of Bangladesh Shishu Hospital & Institute. Results: In our study, we found that almost three fourth (74.0%) patients died and 13(26.0%) patients survived. Majority of our patients were ≤ 15 days and male. We found 22(59.5%) patients had PH level <7.25 in death group and 6(46.2%) in survival group and PH level ≥7.15 was (81.1%) in death group and 10(76.9%) in survival group. Before extubation & death metabolic acidosis was 19(51.4%) in dead group and 2(15.4%) in survival group. Significant relation was found between serum sodium level <135 and outcome of ventilated patients [p=0.039, OR=0.19(0.04-0.89)]. Imbalance of single & more than one electrolyte was found 43.24% & 56.76% in death group and 61.5% & 38.5% in survival group respectively. Conclusion: We found that arterial blood gas analysis & serum electrolytes level provide valuable information for correction of acid–base imbalance associated with a pathological condition. Electrolyte imbalance, regardless of the basic disease etiology, is a significant prognostic indicator that must be rapidly treated in critically ill children to get a good outcome.

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Biochemical Analysis of Electrolytes and Their Role in Paediatric Patients Admitted in Intensive Care Unit (PICU)

Rojekar¹,

Adhe²,

Panot³

et al. 2020

jebmh

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Electrolyte Disturbances in Critically Ill Children Admitted to Paediatric Tertiary Care Centre

Cited by 6 publications

References 22 publications

Hyponatremia and its associated factors in children admitted to the pediatric intensive care unit in eastern Ethiopia: a cross-sectional study

Hyponatremia and its associated factors in children admitted to the pediatric intensive care unit in eastern Ethiopia: a cross-sectional study

Acid-Base Status & Electrolyte Imbalance in Critically ill Ventilated Infants

Biochemical Analysis of Electrolytes and Their Role in Paediatric Patients Admitted in Intensive Care Unit (PICU)

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