BackgroundGlucometers are the excellent tools for self-monitoring of blood glucose (SMBG). They are important especially in the circumstances where continuous monitoring is mandatory and at decision making levels. Tight glycemic control protocols are important for preventing the ill effects of fluctuating glucose levels. This increases the use of glucometers in various healthcare settings. As technology advances, glucometers are getting better in terms of quality of results. But still some lacunae are there.MethodsPresent study was conducted in the tertiary care referral hospital. One hundred twenty five patients were recruited from pediatric wards. Bland-Altman plot, Parke error grid and Surveillance error grid analysis were used for comparing results of glucose meter with that of standard laboratory method.ResultsIt is found that there is significant difference between the results by two methods. Though minimal but glucose meter results deviate from the results of standard lab method. This will affect the overall patient care especially in emergency conditions.ConclusionsThis study is the first of its kind as no similar studies have been reported in the pediatric population. For effective use of glucose meter it should give as accurate as possible estimate of actual glucose levels. Results should not only be accurate but also precise without which critical errors may be possible. We recommend that for any glucose meter there should be regular maintenance as well as calibration is to be done. So that agreement with reference laboratory method is maintained and effective medical decisions are made.
BACKGROUNDFebrile Seizure (FS) is the most common type of childhood seizure, which occurs in 2-5% of neurologically-healthy children between 6 months to 5 years. The exact cause for febrile convulsion is not known, but genetic and environmental factors have influence on its occurrence. Iron deficiency is postulated as a risk factor for febrile seizures in children and it is an easily correctable condition. We therefore studied the association between iron deficiencies in simple febrile seizures.
MATERIALS AND METHODSThis case-control study was done in the Department of Paediatrics of a tertiary care hospital and medical college. Ethical clearance was obtained for the study from the institutional ethical committee.
RESULTSHb, Red Cell Width (RDW) and serum ferritin are significantly among cases and controls. Analysis shows there were 9 cases of recurrent febrile seizures among all cases of seizures. Among these, 2 were having onset earlier than 12 months while remaining 7 had onset between 12-18 months.
CONCLUSIONWe report iron deficiency as a modifiable risk factor for febrile seizures in Indian children of age group 6 months to 5 years. Early detection and timely correction of iron deficiency maybe helpful for prevention of simple febrile seizures in children of this age group.
HOW TO CITE THIS ARTICLE:Potdar S, Junagade S, Panot J, et al. Case-control study of iron deficiency anaemia in febrile seizures.
BACKGROUNDFamilial Hypercholesterolaemia (FH) is a monogenetic autosomal codominant disorder caused by mutation affecting the LDL receptors. It is characterised by elevated LDL cholesterol, xanthomas and early Coronary Artery Disease (CAD). Homozygous Familial Hypercholesterolaemia (HoFH) is of a rare occurrence. Management of HoFH patients requires lifestyle modifications and medical therapy. Untreated homozygous patients rarely survive to adulthood. We report an 8 years old male child who presented with multiple xanthomas over skin since 9 months and had deranged lipid profile consistent with Homozygous FH. On further evaluation, whole family had deranged lipid profile fulfilling criteria of familial hypercholesterolaemia.
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