Electromembrane extraction of stimulating drugs from undiluted whole blood

Jamt, Ragnhild Elén Gjulem; Gjelstad, Astrid; Eibak, Lars Erik Eng; Øiestad, Elisabeth Leere; Christophersen, Asbjørg S.; Rasmussen, Knut; Pedersen‐Bjergaard, Stig

doi:10.1016/j.chroma.2011.08.058

Cited by 63 publications

(37 citation statements)

References 47 publications

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“…During the elution process, because the adsorption of reversed-phase stationary phase for the enriched ionic complex is less than the adsorption of the eluent for the ionic complex, the enriched ionic complex is eluted down [27,28]. In this experiment, when the pure organic solvent was used as an eluent, the eluting efficiency of the eluent declines with the enhancement of the polarity of the eluent (methanol \ ethanol \ acetonitrile \ acetone \ tetrahydrofuran).…”

Section: Mechanism Of Eluting Processmentioning

confidence: 97%

Solid-phase extraction gold from alkaline cyanide solution with quaternary ammonium surfactant

Xie

Yang

et al. 2014

Rare Met.

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The solid-phase extraction (SPE) technique applied to the extraction of organic compound was creatively used as the extraction of inorganic gold in the paper. Two types of techniques were proposed and explored, namely the SPE and the liquid-liquid extraction (LLE) of the quaternary ammonium surfactant [cetytrimethyl ammonium bromide (CTMAB), cetyl pyridine bromide (CPB), benzyl dimethyl dodecyl ammonium chloride (BDMDAC), and dodecyl trimethyl ammonium chloride (DTMAC)]. The surfactant could react with Au(CN) 2 -to form the ionic complex, and the compound could be extracted by SPE column of reversed-phase bonded silica gel. Hence, a new method of SPE was proposed to extract gold with these features of the high selectivity, the reliability, and the simplicity. The experimental result shows that the recovery rate of gold is more than 98 %, and the solid-phase extraction column is not easily damaged and it can be repeatedly used. The new method can be used as the extraction process of gold from alkaline cyanide solution as well. Besides, the paper also puts forward a new process of gold extraction.

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Section: Mechanism Of Eluting Processmentioning

confidence: 97%

Solid-phase extraction gold from alkaline cyanide solution with quaternary ammonium surfactant

Xie

Yang

et al. 2014

Rare Met.

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“…Over the past decades, minimization of organic solvents consumed in the sample preparation has become a major trend. Therefore, several eco-friendly sample pretreatment techniques such as liquid phase microextraction [12][13][14][15][16], electromembrane extraction [17,18], supercritical fluid extraction [19], stir bar sorptive extraction [20] and solidphase microextraction (SPME) [21] were employed as alternatives for the extraction of amphetamines from biological matrices.…”

Section: Introductionmentioning

confidence: 99%

Determination of amphetamines in biological samples using electro enhanced solid-phase microextraction-gas chromatography

Zeng

Chen

et al. 2015

Journal of Chromatography B

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“…Due to use of a little amount of organic solvent (microliter), EME is environmentally friendly extraction technique . Up to date, EME has been used for the extraction of drugs , environmental pollutants , metals and ions , amino acids and peptides from different matrices. Several analytical methods such as HPLC , UPLC , LC‐MS/MS , CZE and RIA were reported for determination of some Gn‐RH agonists in different sample matrices.…”

Section: Introductionmentioning

confidence: 99%

Electromembrane extraction of gonadotropin‐releasing hormone agonists from plasma and wastewater samples

et al. 2016

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In the present study, for the first time electromembrane extraction followed by high performance liquid chromatography coupled with ultraviolet detection was optimized and validated for quantification of four gonadotropin-releasing hormone agonist anticancer peptides (alarelin, leuprolide, buserelin and triptorelin) in biological and aqueous samples. The parameters influencing electromigration were investigated and optimized. The membrane consists 95% of 1-octanol and 5% di-(2-ethylhexyl)-phosphate immobilized in the pores of a hollow fiber. A 20 V electrical field was applied to make the analytes migrate from sample solution with pH 7.0, through the supported liquid membrane into an acidic acceptor solution with pH 1.0 which was located inside the lumen of hollow fiber. Extraction recoveries in the range of 49 and 71% within 15 min extraction time were obtained in different biological matrices which resulted in preconcentration factors in the range of 82-118 and satisfactory repeatability (7.1 < RSD% < 19.8). The method offers good linearity (2.0-1000 ng/mL) with estimation of regression coefficient higher than 0.998. The procedure allows very low detection and quantitation limits of 0.2 and 0.6 ng/mL, respectively. Finally, it was applied to determination and quantification of peptides in human plasma and wastewater samples and satisfactory results were yielded.

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Electromembrane extraction of stimulating drugs from undiluted whole blood

Cited by 63 publications

References 47 publications

Solid-phase extraction gold from alkaline cyanide solution with quaternary ammonium surfactant

Solid-phase extraction gold from alkaline cyanide solution with quaternary ammonium surfactant

Determination of amphetamines in biological samples using electro enhanced solid-phase microextraction-gas chromatography

Electromembrane extraction of gonadotropin‐releasing hormone agonists from plasma and wastewater samples

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