Electron Microscopy of Unstable Inclusions Induced in Maize by Maize Dwarf Mosaic Virus

Langenberg, Willem G.; Schroeder, Helen F.

doi:10.1094/phyto-63-1066

Cited by 8 publications

(2 citation statements)

References 24 publications

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“…No other major cellular changes were noticeable between the microscopic ultra sections prepared from SMV-inoculated resistant and susceptible cultivars. In wheat, the pinwheel structures associated with Wheat spindle streak virus infection are considered to be derived from the endoplasmic reticulum (ER; Langenberg and Schroeder, 1973).…”

Section: Smv Infection Is Associated With the Induction Of Uprassociamentioning

confidence: 99%

The Potyviral P3 Protein Targets Eukaryotic Elongation Factor 1A to Promote the Unfolded Protein Response and Viral Pathogenesis

et al. 2016

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The biochemical function of the potyviral P3 protein is not known, although it is known to regulate virus replication, movement, and pathogenesis. We show that P3, the putative virulence determinant of soybean mosaic virus (SMV), targets a component of the translation elongation complex in soybean. Eukaryotic elongation factor 1A (eEF1A), a well-known host factor in viral pathogenesis, is essential for SMV virulence and the associated unfolded protein response (UPR). Silencing GmEF1A inhibits accumulation of SMV and another ER-associated virus in soybean. Conversely, endoplasmic reticulum (ER) stress-inducing chemicals promote SMV accumulation in wild-type, but not GmEF1A-knockdown, plants. Knockdown of genes encoding the eEF1B isoform, which is important for eEF1A function in translation elongation, has similar effects on UPR and SMV resistance, suggesting a link to translation elongation. P3 and GmEF1A promote each other's nuclear localization, similar to the nuclearcytoplasmic transport of eEF1A by the Human immunodeficiency virus 1 Nef protein. Our results suggest that P3 targets host elongation factors resulting in UPR, which in turn facilitates SMV replication and place eEF1A upstream of BiP in the ER stress response during pathogen infection.

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Section: Smv Infection Is Associated With the Induction Of Uprassociamentioning

confidence: 99%

The Potyviral P3 Protein Targets Eukaryotic Elongation Factor 1A to Promote the Unfolded Protein Response and Viral Pathogenesis

et al. 2016

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“…Isolate MDMV-Spl produced, in addition, aggregate laminates, and this type could be observed more clearly when samples were cold embedded. This could indicate that laminated aggregates are unstable (Langenberg and Schroeder, 1973). Given that isolate MDMV-Spl induced the four types of CI described in potyviruses (Edwarson and Ko, 1984), and that it induced similar reactions in sorghum cultivars to other isolates of MDMV from the USA and from Europe, it is clear that the morphology of CIs must be used in combination with other tests.…”

Section: Discussionmentioning

confidence: 99%

Biological characteristics of maize dwarf mosaic potyvirus from Spain

et al. 1996

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Two isolates of maize dwarf mosaic virus (MDMV-Sp and MDMV-Spl) obtained from maize in the northeast of Spain were studied. Both isolates induced similar reactions on 6 sorghum cultivars, johnsongrass and oat (cv. Clintland), with the exception of MDMV-Sp which produced a different reaction on one sorghum cultivar. Thirtythree grass species were tested as possible hosts (16 previously untested) and 18 were found to be susceptible. Among those, eight were previously unidentified hosts for MDMV: Aegilops ovata, A. ventricosa, Avena barbata, Bromus alopecurus, B. diandrus, B. fasciculatus, Echinaria capitata and Lolium rigidum. Both isolates were transmitted from maize to maize nonpersistently by Rhopalosiphum maidis, R. padi, Schizaphis graminum and Sitobium avenae. The virus was not seed-transmitted in Mo17 and B73 maize inbred lines. Pinwheels, scrolls and short curved laminated aggregates were observed in the cytoplasm of maize cells infected by MDMV-Sp or MDMV-Spl. In addition, laminated aggregates were observed in cells infected by MDMV-Spl.

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Cytopathology

Lesemann¹

1988

The Plant Viruses

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Electron Microscopy of Unstable Inclusions Induced in Maize by Maize Dwarf Mosaic Virus

Cited by 8 publications

References 24 publications

The Potyviral P3 Protein Targets Eukaryotic Elongation Factor 1A to Promote the Unfolded Protein Response and Viral Pathogenesis

The Potyviral P3 Protein Targets Eukaryotic Elongation Factor 1A to Promote the Unfolded Protein Response and Viral Pathogenesis

Biological characteristics of maize dwarf mosaic potyvirus from Spain

Cytopathology

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