2015
DOI: 10.1016/j.jinorgbio.2015.06.014
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Electron self-exchange in hemoglobins revealed by deutero-hemin substitution

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Cited by 7 publications
(14 citation statements)
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“…This would both eliminate the need for a dedicated reductase and link the activity of GlbN to a probable source of NO, the Fd-dependent nitrate reductase (NarB). In addition, the bis –histidine hexacoordination mode observed in GlbN and GlbN-A facilitates ET [49, 73, 74], which is a necessary step for NOD turnover (Equation 1c). …”
Section: Discussionmentioning
confidence: 99%
“…This would both eliminate the need for a dedicated reductase and link the activity of GlbN to a probable source of NO, the Fd-dependent nitrate reductase (NarB). In addition, the bis –histidine hexacoordination mode observed in GlbN and GlbN-A facilitates ET [49, 73, 74], which is a necessary step for NOD turnover (Equation 1c). …”
Section: Discussionmentioning
confidence: 99%
“…The reduction of NH 2 OH to NH 4 + involves the transfer of two electrons (Fig. b) and thus requires intermolecular electron exchange between Glb subunits (Athwal et al , ). This reaction could potentially serve anaerobic metabolism by providing a step along the pathway of fermentative ammonification.…”
Section: Globins Of Angiospermsmentioning
confidence: 99%
“…The reaction requires two electrons, and previous work has shown that these electrons can originate solely from ferrous Phyt 2+ molecules (reaction ). , …”
mentioning
confidence: 99%
“…Phyt is particularly efficient at HA reduction because of its higher affinity for HA, and its rapid intermolecular electron exchange rate compared to those of other Hbs. , A molecular attribute of Phyt implicated in these features is facile intramolecular reversible “hexacoordination” of the heme iron by a histidine side chain located near the ligand binding site. It has been proposed that weak hexacoordination might be necessary to allow HA binding and to facilitate reduction of the heme iron.…”
mentioning
confidence: 99%