Electroosmotic pumps and their applications in microfluidic systems

Wang, Xiayan; Cheng, Chun; Wang, Shili; Liu, Shaorong

doi:10.1007/s10404-008-0399-9

Cited by 302 publications

(215 citation statements)

References 97 publications

(124 reference statements)

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“…The net charge in this ionic layer depends on the electrolyte and the chemistry of the surface, and directly affects the velocity of flow generated per unit of electric field (the electroosmotic mobility). These pumps are most commonly associated with analytic chemistry and microfluidics, since they are compact, easily integrated into small devices, and can be implemented in a wide range of applications for micro-high-pressure liquid chromatography (µHPLC), capillary electrophoresis, chip-based assays, drug delivery, and device actuation (Chen et al 2004;Glawdel and Ren 2009;Li and Harrison 1997;Litster et al 2010;Manz et al 1994;Wang et al 2009;Zeng et al 2001). …”

Section: Introductionmentioning

confidence: 99%

A large-area, all-plastic, flexible electroosmotic pump

Bengtsson

Robinson

2017

Microfluid Nanofluid

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A large-area, fabric-like pump would potentially have applications, for example, in controlling water transport through a garment, such as a rain jacket, regardless of the external temperature and humidity. This paper presents an all-plastic, flexible electroosmotic pump, constructed from commercially available materials: A polycarbonate membrane combined with the electrochemically active polymer poly(3,4-ethylenedioxythiophene) polystyrene sulfonate that actively transports water using an electric potential that can be supplied by a small battery. By using electrochemically active polymer electrodes instead of metal electrodes, the electrochemical reaction that drives flow avoids the oxygen and hydrogen gas production or pH changes associated with water electrolysis. We observe a water mass flux up to 23 mg min −1 per cm 2 polycarbonate membrane (porosity 10-15%), at an applied potential of 5 V, and a limiting operating pressure of 0.3 kPa V −1 , similar to previously reported membrane-based electroosmotic pumps.

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Section: Introductionmentioning

confidence: 99%

A large-area, all-plastic, flexible electroosmotic pump

Bengtsson

Robinson

2017

Microfluid Nanofluid

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“…Air-forced cooling cannot remove such high heat flux from the hot chip. Micropumping that drives liquid fluids through microchannels is an efficient approach to perform heat dissipation of electronic components [10][11][12].…”

Section: Microelectronic Thermal Managementmentioning

confidence: 99%

Electroosmotic Flow Pump

Gao¹,

Gui²

2016

Advances in Microfluidics - New Applications in Biology, Energy, and Materials Sciences

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Electroosmotic flow (EOF) pumping has been widely used to manipulate fluids such as liquid sample reagents in microfluidic systems. In this chapter, we will introduce the research progress on EOF pumps in the fields of microfluidic science and technology and briefly present their microfluidic applications in recent years. The chapter focuses on pump channel materials, electrodes, and their fabrication techniques in microfluidics.

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“…Some of the advantages of EO pumps are that they have no moving parts, are capable of generating high flow rates, and are relatively easy to integrate into LOC devices. 107 Moreover, EO-pumps are capable of generating high pressures and can be designed to resist undesired pressure-driven flow. As described above, they require a channel with a charged surface and small diameter (or a network of such channels as in the clay particles studied by Reuss), and an electrolytic fluid.…”

Section: Electroosmotic Pumpsmentioning

confidence: 99%

Electrodes and Electrokinetic Systems for Biotechnological Applications

Nilsson¹

2015

Linköping Studies in Science and Technology. Dissertations

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Research in bioelectronics studies biological systems and materials in combination with electronic interfaces for the development of devices, e.g., for medical applications, drug and toxicity tests, and biotechnology in general. Neural implants and pacemakers are examples of products developed from this area of research. Conducting polymers such as poly(3,4-ethylenedioxythiophene) (PEDOT) bridge biology and electronics with a combination of biocompatibility, flexibility, and capability to themselves undergo redox reactions. Electrokinetics, a related branch of science, describes the motion of fluids and particles caused by the application of an electric field, and includes various separation techniques such as gel electrophoresis. Applying an electric field in a sufficiently small diameter silica capillary can cause the liquid in the capillary to move. This phenomenon, referred to as electroosmosis, plays an important role in miniaturized microfluidic systems and can be used to drive flow in a so-called electroosmotic pump.This thesis describes research at the interface between biology, chemistry and electronics. The first two papers probe the adsorption mechanism of poly-L-lysine, often used in biotechnological applications, onto hard materials such as metals (platinum) and metal oxides (indium tin oxide). By employing a gravimetric technique, quartz crystal microgravimetry with dissipation monitoring (QCM-D) combined with electrochemistry, we studied the process by which poly-L-lysine is deposited onto two different conducting substrates under anodic conditions. We found that indium tin oxide is more suitable than platinum for anodic electrodeposition of PLL, however, the exact film deposition mechanism is not fully understood. Paper 3 demonstrates the applicability of using conducting polymers, (e.g., PEDOT) instead of platinum as electrode material in gel electrophoresis. The last paper describes the fabrication and characterization of an electroosmotic pump consisting of a potassium silicate stationary phase in a fused silica capillary and the integration of the pump into a system for use, e.g., as a bioreactor. Populärvetenskaplig sammanfattningBiologi och elektronik har historiskt varit två separata forskningsområden som i nuläget till stor del även kombineras inom fältet bioelektronik. Ett viktigt exempel inom bioelektroniken är utvecklingen av pacemakern under 1950-talet. Andra exempel på applikationer är bl. a. biosensorer, neurologiska implantat och miniatyriserade analyssystem, s.k. Lab-On-a-Chip. Inom bioelektronik syftar man till att studera och påverka biologiska system och material med elektroteknik. År 2000 gavs Nobelpriset i kemi till Heeger, MacDiarmid och Shirakawa för deras utveckling av elektriskt ledande polymerer samt möjligheten att öka dess ledningsförmåga genom en process som kallas dopning. Konjugerade polymerer såsom poly(3,4-ethylenedioxythiophene) (PEDOT) är viktiga verktyg för att binda samman biologi med elektronik genom deras flexibilitet, biokompatibilitet samt förmågan...

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Electroosmotic pumps and their applications in microfluidic systems

Cited by 302 publications

References 97 publications

A large-area, all-plastic, flexible electroosmotic pump

A large-area, all-plastic, flexible electroosmotic pump

Electroosmotic Flow Pump

Electrodes and Electrokinetic Systems for Biotechnological Applications

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