Electrooxidation and determination of flufenamic acid at graphene oxide modified carbon electrode

Shetti, Nagaraj P.; Nayak, Deepti S.; Malode, Shweta J.; Kulkarni, Raviraj M.; Kulkarni, Dipak B.; Teggi, Rupa A.; Joshi, Varun V.

doi:10.1016/j.surfin.2017.08.008

Cited by 69 publications

(26 citation statements)

References 52 publications

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“…When developing new voltammetric sensors, various modification methods can be used to increase the sensitivity of analyte determination. For example, you can use the electrochemical pretreated electrodes, carbon nanomaterials, metal nanoparticles and their oxides, as well as materials that increase the sorption of analyte on the surface of the electrode…”

Section: Introductionmentioning

confidence: 99%

Determination of Carmoisine onto Carbon‐Paste Electrode Modified by Silica Impregnated with Cetylpyridinium Chloride

2020

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In this paper a simple, cheap and sensitive electrochemical sensor for determination of Carmoisine in soft drinks was developed. Carmoisine is a synthetic azo dye which is used in food products. In this work effective voltammetric sensor based on carbon‐paste electrode modified by silica impregnated with cetylpyridinium chloride to increase the sensitivity of Carmoisine detection was proposed. The voltammetric behavior of Carmoisine, the number of protons and electrons involved in the oxidation process were studied. The probable mechanism of Carmoisine oxidation on the developed sensor was suggested. The optimal conditions for the square‐wave voltammetric determination of Carmoisine onto developed sensor were found to be: pH=2; Eads=400 mV; tads=300s; A=50 mV; ν=25 Hz, υ=100 mV/s. The calibration curve was linear in the range of Carmoisine concentrations 0,08‐1 μM. The proposed method was successfully tested in the analysis of Carmoisine in soft drinks with RSD not more than 5%.

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Section: Introductionmentioning

confidence: 99%

Determination of Carmoisine onto Carbon‐Paste Electrode Modified by Silica Impregnated with Cetylpyridinium Chloride

2020

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“… 159 Considering that GO is an ultra-highly efficient quencher in fluorescence or chemiluminescence body experiments, but also an electron transfer facilitator, and can be reduced and/or functionalized, the future of functionally hybridized GO is quite bright for its use in biosensing, since much interest is given to immobilization techniques for the fabrication of G-based electrochemical biosensors. 139 , 160 - 162 In a study, a multimodal probe based on bovine-serum-albumin-capped fluorine functionalized graphene quantum dots ( BSA@FGQDs ) was developed. This new fluorescent probe can monitor amyloid peptide monomers/oligomers with more sensitivity compared with previous ones.…”

Section: Graphene and Graphene Derivatives: Malleable Giants Nanomatementioning

confidence: 99%

Graphene, an Interesting Nanocarbon Allotrope for Biosensing Applications: Advances, Insights, and Prospects

Menaa

Yazdian

Vashist

et al. 2021

Biomed Eng Comput Biol

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Graphene, a relatively new two-dimensional (2D) nanomaterial, possesses unique structure (e.g. lighter, harder, and more flexible than steel) and tunable physicochemical (e.g. electronical, optical) properties with potentially wide eco-friendly and cost-effective usage in biosensing. Furthermore, graphene-related nanomaterials (e.g. graphene oxide, doped graphene, carbon nanotubes) have inculcated tremendous interest among scientists and industrials for the development of innovative biosensing platforms, such as arrays, sequencers and other nanooptical/biophotonic sensing systems (e.g. FET, FRET, CRET, GERS). Indeed, combinatorial functionalization approaches are constantly improving the overall properties of graphene, such as its sensitivity, stability, specificity, selectivity, and response for potential bioanalytical applications. These include real-time multiplex detection, tracking, qualitative, and quantitative characterization of molecules (i.e. analytes [H2O2, urea, nitrite, ATP or NADH]; ions [Hg2+, Pb2+, or Cu2+]; biomolecules (DNA, iRNA, peptides, proteins, vitamins or glucose; disease biomarkers such as genetic alterations in BRCA1, p53) and cells (cancer cells, stem cells, bacteria, or viruses). However, there is still a paucity of comparative reports that critically evaluate the relative toxicity of carbon nanoallotropes in humans. This manuscript comprehensively reviews the biosensing applications of graphene and its derivatives (i.e. GO and rGO). Prospects and challenges are also introduced.

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“…In addition, ISEs are non-destructive tools [18][19][20]. The carbon paste electrodes (CPEs) are suggested as useful end point indicator electrode in the potentiometric titration of drugs [21][22][23][24][25][26]. CPEs had the advantages of very low Ohmic resistance, very short response time in addition to the ease of fabrication and regeneration as well as long functional lifetime compared to PVC and coated wire electrodes.…”

Section: Introductionmentioning

confidence: 99%

Potentiometric determination of mepivacaine hydrochloride local anesthetic drug in pharmaceutical and biological fluids using ion selective electrode

Ali

El-Hamid

2021

Egypt. J. Chem.

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The objective of this work is to determine mepivacaine hydrochloride (MPVHC) as local anesthetic drug. Modified carbon paste ion-selective electrode was used for the determination of MPVHC in different dosage forms and biological fluids. The study depends on potentiometric titration of MPVHC drug using modified carbon paste (MCPE) as end point indicator electrode. The effects of the paste composition, different conditioning parameters and foreign ions on the electrode performance were investigated and response time of the electrode has been studied. The results obtained showed that carbon paste electrode modified with sodium tetraphenyl borate-MPV ion pair gives the highest potential break at the end point, Nernstian slope, wide concentration range and lower detection limit than the reinckate-, phosphotungestic-and phosphomolybdic-MPV ion pairs. The fabricated electrode obtained Nernstian response of 57.71±0.67 mV decade -1 in the concentration range of 3.1×10 -7 -1.0×10 -1 mol L -1 for MCPE electrode. The electrode was found to be operating within the pH range of 3.0-8.0 and exhibited a fast response time (about 14 s), low detection limit of 3.1×10 -7 mol L -1 and long lifetime (98 days). The electrode showed high selectivity to the MPVHC drug in the presence of different organic, inorganic and amino acids. The electrode was successfully applied for the determination of MPVHC in pharmaceutical preparations and biological fluids (urine and plasma) with high percent recovery and low standard and relative standard deviation values. The results obtained applying this potentiometric electrode are comparable with British pharmacopeia. The method validation parameters were optimized and the method can be applied for routine analysis of MPVHC drug.

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Electrooxidation and determination of flufenamic acid at graphene oxide modified carbon electrode

Cited by 69 publications

References 52 publications

Determination of Carmoisine onto Carbon‐Paste Electrode Modified by Silica Impregnated with Cetylpyridinium Chloride

Determination of Carmoisine onto Carbon‐Paste Electrode Modified by Silica Impregnated with Cetylpyridinium Chloride

Graphene, an Interesting Nanocarbon Allotrope for Biosensing Applications: Advances, Insights, and Prospects

Potentiometric determination of mepivacaine hydrochloride local anesthetic drug in pharmaceutical and biological fluids using ion selective electrode

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