Electrophoretic co-deposition of PEEK-hydroxyapatite composite coatings for biomedical applications

Baştan, Fatih Erdem; Avcu, Yasemin Yıldıran; Avcu, Egemen; Üstel, Fatih

doi:10.1016/j.colsurfb.2018.05.005

Cited by 94 publications

(87 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PEEK consists of an aromatic backbone molecular chain, interconnected by ketone and ether functional groups . PEEK is compatible with bioactive inorganic materials, including hydroxyapatite and bioactive glasses (BGs), which can be used either as a composite filler or as surface coating . In addition, PEEK/BG composite layers can act as substrate to be further coated with biodegradable composite coatings loaded with antibiotics to provide improved surfaces for antiseptic bonding to tissues …”

Section: Introductionmentioning

confidence: 99%

“…[14][15][16][17] PEEK is compatible with bioactive inorganic materials, including hydroxyapatite and bioactive glasses (BGs), which can be used either as a composite filler or as surface coating. 13,18,19 In addition, PEEK/BG composite layers can act as substrate to be further coated with biodegradable composite coatings loaded with antibiotics to provide improved surfaces for antiseptic bonding to tissues. 20,21 Natural polymers are promising candidates for biomedical applications.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Electrophoretic deposition of lawsone loaded bioactive glass (BG)/chitosan composite on polyetheretherketone (PEEK)/BG layers as antibacterial and bioactive coating

Rehman

Baştan

Nawaz

et al. 2018

J Biomedical Materials Res

Self Cite

View full text Add to dashboard Cite

In this study, chitosan/bioactive glass (BG)/lawsone coatings were deposited by electrophoretic deposition (EPD) on polyetheretherketone (PEEK)/BG layers (previously deposited by EPD on 316-L stainless steel) to produce bioactive and antibacterial coatings. First, the EPD of chitosan/BG/lawsone was optimized on stainless steel in terms of suspension stability, homogeneity and thickness of coatings. Subsequently, the optimized EPD parameters were used to produce bioresorbable chitosan/bioactive glass (BG)/lawsone coatings on PEEK/BG layers. The produced layered coatings were characterized in terms of composition, microstructure, corrosion resistance, in vitro bioactivity, drug release kinetics and antibacterial activity. Ultraviolet/Visible (UV/VIS) spectroscopic analyses confirmed the release of lawsone from the coatings. Moreover, the deposition of chitosan/BG coatings was confirmed by Scanning Electron Microscopy (SEM) and Fourier Transform Infrared spectroscopy (FTIR). The coated specimens presented higher corrosion resistance (10 times) in comparison to that of bare 316-L stainless steel and showed convenient wettability for initial protein attachment. The presence of lawsone in the top layer provided antibacterial effects against Staphylococcus carnosus. Moreover, the developed coatings formed apatite-like crystals upon immersion in simulated body fluid, indicating the possibility of achieving close interaction between the coating surface and bone. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 3111-3122, 2018.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Electrophoretic deposition of lawsone loaded bioactive glass (BG)/chitosan composite on polyetheretherketone (PEEK)/BG layers as antibacterial and bioactive coating

Rehman

Baştan

Nawaz

et al. 2018

J Biomedical Materials Res

Self Cite

View full text Add to dashboard Cite

show abstract

“…Many types of research have been conducted on producing and commercialization of the bioceramic coatings for the permanent metal implants. Among the various techniques, the EPD method has attracted great attention for applying the HA coating due to its low cost, simplicity, uniformity of coating, low process time and temperature . The later heat treatment process after EPD is required to increase the coating density and adhesion strength between the coating and substrate through the chemical bonding .…”

Section: Introductionmentioning

confidence: 99%

“…Among the various techniques, the EPD method has attracted great attention for applying the HA coating due to its low cost, simplicity, uniformity of coating, low process time and temperature. [14][15][16][17] The later heat treatment process after EPD is required to increase the coating density and adhesion strength between the coating and substrate through the chemical bonding. [17] Sintering at high temperatures (1,200°C) could cause the HA coating decomposition on the metal substrate.…”

Section: Introductionmentioning

confidence: 99%

“…[14][15][16][17] The later heat treatment process after EPD is required to increase the coating density and adhesion strength between the coating and substrate through the chemical bonding. [17] Sintering at high temperatures (1,200°C) could cause the HA coating decomposition on the metal substrate. [11] While the insufficient low-temperature results in a low mechanical strength as well as the chemical instability of coating.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of hydroxyapatite‐titanium‐MWCNTs composite coating fabricated by electrophoretic deposition on corrosion and cellular behavior of NiTi alloy

Maleki-Ghaleh

Khalil‐Allafi

2019

Materials & Corrosion

View full text Add to dashboard Cite

In this study, the hydroxyapatite (HA)‐titanium (Ti, 20 wt.%) multiwalled carbon nanotubes (MWCNTs, 1 wt.%) composite coating was applied on the NiTi alloy by using the electrophoretic deposition (EPD) technique. The morphologies and the phase structures of the coatings were investigated by the FESEM and XRD analysis, respectively. The corrosion behaviors of the coated NiTi samples were investigated using the polarization and electrochemical impedance spectroscopy tests in a simulated body fluid (SBF). The amounts of the released Ni ions from the coated NiTi were studied in the SBF. The results of the electrochemical tests revealed the corrosion resistance of the NiTi coated with HA was further improved by the addition of the Ti and MWCNTs to the HA coating. The current density and corrosion resistance of the NiTi alloy changed from 2.52 μA.cm−2 and 24.13 kΩ to 0.91 nA.cm−2 and 5.92 MΩ after coated with the HA‐Ti‐MWCNTs composite coating. Also, the number of nickel ions released from the surface of the NiTi alloy to the SBF medium suppressed from 11.8 to 0.08 μgr.L−1, after coating with HA‐Ti‐MWCNTs. Also, the cellular proliferation in the culture medium consisting of the NiTi alloy coated with the HA‐Ti‐MWCNTs improved significantly (compared with that of the NiTi alloy) as shown no toxicity in the cell culture medium.

show abstract

Antibacterial effect of nanometer‐size grafted layer of quaternary ammonium polymer on poly(ether ether ketone) substrate

Oai

Inoue

Nakao

et al. 2020

J of Applied Polymer Sci

View full text Add to dashboard Cite

Owing to its excellent physicochemical properties, poly(ether ether ketone) (PEEK) has been used clinically for medical implants. However, its surface properties should be improved to further enhance its compatibility with a living organism and infection resistance. Here, we examined the surface construction via a combined process, that is, the self‐initiated photoinduced graft polymerization of N,N‐dimethylaminoethyl methacrylate (DMA) on PEEK substrate followed by polymer quaternization using various bromoalkanes (Q‐PDMA‐g‐PEEK). Using a Fourier transform infrared spectroscopy and X‐ray photoelectron spectroscopy, the grafting and quaternarization of poly(DMA) (PDMA) on the PEEK substrate was confirmed. The degree of quaternizations was at least 60% even when the various bromoalkanes were reacted. The Q‐PDMA‐g‐PEEK with 1‐bromooctane (BrC8) (C8‐Q‐PDMA‐g‐PEEK) substrate exhibited the highest ζ‐potential of other Q‐PDMA‐g‐PEEK substrates. However, no significant differences were observed in the degree of quaternization, thickness of the polymer layer, and hydrophilicity of all modified PEEK substrates. In addition, from antibacterial test with Escherichia coli, the C8Q‐PDMA‐g‐PEEK substrate exhibited the highest antibacterial rate (80%) among Q‐PDMA‐g‐PEEK substrates examined. Therefore, we concluded that the surface ζ‐potential is the one an important parameter for manufacturing PEEK substrates with bactericidal properties.

show abstract

Electrophoretic co-deposition of PEEK-hydroxyapatite composite coatings for biomedical applications

Cited by 94 publications

References 61 publications

Electrophoretic deposition of lawsone loaded bioactive glass (BG)/chitosan composite on polyetheretherketone (PEEK)/BG layers as antibacterial and bioactive coating

Electrophoretic deposition of lawsone loaded bioactive glass (BG)/chitosan composite on polyetheretherketone (PEEK)/BG layers as antibacterial and bioactive coating

Effect of hydroxyapatite‐titanium‐MWCNTs composite coating fabricated by electrophoretic deposition on corrosion and cellular behavior of NiTi alloy

Antibacterial effect of nanometer‐size grafted layer of quaternary ammonium polymer on poly(ether ether ketone) substrate

Contact Info

Product

Resources

About