Electrophoretic coating of hydroxyapatite on titanium implants

Stoch, A.; Brożek, A.; Kmita, Grzegorz; Stoch, J.; Jastrzębski, Witold; Rakowska, A.

doi:10.1016/s0022-2860(01)00716-5

Cited by 152 publications

(80 citation statements)

References 8 publications

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“…[1][2][3][4][5][6][7][8][9] Such composites are widely used, because they have a capability to integrate directly into bone tissues through the processes of resorption and/or the processes of formation of a new bone on the surface of implant covered by calcium hydroxyapatite. [10][11][12][14][15][16] A variety of methods [17][18][19][20][21][22][23][24][25][26][27] can be used for the synthesis of calcium hydroxyapatite films, such as electrophoretic deposition, 17) electrocrystallization, 18) plasma spray deposition, 19,20) flame spray deposition, 19) magnetic field spattering, 21) deposition by aging in fluids like SBF fluids, 14) ion beam spattering, 22,23) laser beam spattering, 24) electron beam evaporation, 25) sol-gel, 26) aerosol-gel 27) and hydrothermal synthesis. 8,13) Most of these methods are expensive vacuumbased techniques, with problems related to the film homogeneity, require batch processing and usually high-vapourpressure chemicals or high purity targets as starting materials.…”

Section: Introductionmentioning

confidence: 99%

Calcium Hydroxyapatite Thin Films on Titanium Substrates Prepared by Ultrasonic Spray Pyrolysis

Jokanovic

Uskokovic

2005

Mater. Trans.

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Calciumhydroxyapatite thin films have been prepared by ultrasonic spray pyrolysis deposition on titanium substrate. The surface morphologies of the films formed at different deposition times were analysed by using SEM. The mechanism of the films formation was investigated in relation to the observed film morphology during the first stages of its formation, as well as to its consolidation to the final form. The chemical homogeneity of the synthesized films was determined by using EDS analysis, whereas the phase composition was determined by using XRD measurements and IR spectroscopy. The roughnesses and the thicknesses of the films were analysed by using surface profiler method. The continuous morphology films are obtained only for samples deposited more than 1.5 h.

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Section: Introductionmentioning

confidence: 99%

Calcium Hydroxyapatite Thin Films on Titanium Substrates Prepared by Ultrasonic Spray Pyrolysis

Jokanovic

Uskokovic

2005

Mater. Trans.

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“…The medium used for electrophoretic deposition is made of organic solvents such as isopropanol or ethanol [198,199]. This technique is a submersion method and so it allows for coating of, e.g., porous implants.…”

Section: Electrochemical Deposition Techniquesmentioning

confidence: 99%

Surface Engineering for Bone Implants: A Trend from Passive to Active Surfaces

et al. 2012

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Abstract:The mechanical and biological properties of bone implants need to be optimal to form a quick and firm connection with the surrounding environment in load bearing applications. Bone is a connective tissue composed of an organic collagenous matrix, a fine dispersion of reinforcing inorganic (calcium phosphate) nanocrystals, and bone-forming and -degrading cells. These different components have a synergistic and hierarchical structure that renders bone tissue properties unique in terms of hardness, flexibility and regenerative capacity. Metallic and polymeric materials offer mechanical strength and/or resilience that are required to simulate bone tissue in load-bearing applications in terms of maximum load, bending and fatigue strength. Nevertheless, the interaction between devices and the surrounding tissue at the implant interface is essential for success or failure of implants. In that respect, coatings can be applied to facilitate the process of bone healing and obtain a continuous transition from living tissue to the synthetic implant. Compounds that are inspired by inorganic (e.g., hydroxyapatite crystals) or organic (e.g., collagen, extracellular matrix components, enzymes) components of bone tissue, are the most obvious candidates for application as implant coating to improve the performance of bone implants. This review provides an overview of recent trends and strategies in surface engineering that are currently investigated to improve the biological performance of bone implants in terms of functionality and biological efficacy. OPEN ACCESSCoatings 2012, 2 96

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“…Hydroxyapatite (HA), Ca 10 (PO 4 ) 6 (OH) 2 , is widely applied as a component of medical and dental devices [1] [2] [3] [4] [5] owing to its excellent bone repairing ability via activating osteoblasts. However, it has been pointed out that the main component of bones and teeth, which is called biological apatite (BA), is not stoichiometrically-pure HA but variously-substituted HA.…”

Section: Introductionmentioning

confidence: 99%

Systematic Relationship between Sr Content and the Lattice Constants in Sr Substituted Hydroxyapatite Thin Films

Nishikawa¹,

Saito²,

Miyake³

et al. 2017

JCPT

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To increase the biocompatibility of hydroxyapatite (HA), Ca 10 (PO 4 ) 6 (OH) 2 , the Sr substitution of Ca into the HA structure was effected to yield Ca 10−x Sr x (PO 4 ) 6 (OH) 2 (Sr-HA). For medical and dental applications, it is important that Sr-HA is prepared as a thin film so that the Sr fully substitutes the Ca sites in the HA structure and does not form segregated impurities consisting of Sr compounds. If the segregated Sr forms different amounts of different impurities, the dissolution of the Sr into the living body will not be reproducible across different samples. To confirm the Sr substitution into the Ca site in the HA structure, the systematic variation in the lattice constants of the Sr-HA with Sr content was evaluated as the first step. The a-and c-axis lengths were found to exhibit a linear relationship with the Sr content for six samples with different Sr contents, indicating that the prepared Sr-HA thin films likely possessed partial Sr substitution into the Ca sites of the HA structure. This result is an important first step in the accurate evaluation of the biological effects of Sr-HA thin films.

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Electrophoretic coating of hydroxyapatite on titanium implants

Cited by 152 publications

References 8 publications

Calcium Hydroxyapatite Thin Films on Titanium Substrates Prepared by Ultrasonic Spray Pyrolysis

Calcium Hydroxyapatite Thin Films on Titanium Substrates Prepared by Ultrasonic Spray Pyrolysis

Surface Engineering for Bone Implants: A Trend from Passive to Active Surfaces

Systematic Relationship between Sr Content and the Lattice Constants in Sr Substituted Hydroxyapatite Thin Films

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