Electrophoretic deposition of chitosan/bioactive glass/silica coatings on stainless steel and WE43 Mg alloy substrates

Heise, Susanne; Wirth, T.; Höhlinger, Michael; Torres, Yadir; Ortiz, Jose Antonio Rodriquez; Wagener, Victoria; Virtanen, Sannakaisa; Boccaccını, Aldo R.

doi:10.1016/j.surfcoat.2018.03.050

Cited by 63 publications

(26 citation statements)

References 44 publications

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“…Chitosan is a natural cationic polymer, which is derived from chitin through N ‐deacetylation. Chitosan is a biodegradable, biocompatible biopolymer for applications in drug delivery systems and tissue engineering, which can accelerate wound healing owing to its biocompatibility and antibacterial effects . Electrophoretic deposition (EPD) is a widely adopted method for depositing inorganic particles, biopolymers and combination of both .…”

Section: Introductionmentioning

confidence: 99%

“…Chitosan is a biodegradable, biocompatible biopolymer for applications in drug delivery systems and tissue engineering, which can accelerate wound healing owing to its biocompatibility and antibacterial effects. [22][23][24] Electrophoretic deposition (EPD) is a widely adopted method for depositing inorganic particles, biopolymers and combination of both. 25,26 EPD harnesses the motion of charged particles or molecules in a liquid medium under the application of an electric field.…”

Section: Introductionmentioning

confidence: 99%

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Electrophoretic deposition of lawsone loaded bioactive glass (BG)/chitosan composite on polyetheretherketone (PEEK)/BG layers as antibacterial and bioactive coating

Rehman

Baştan

Nawaz

et al. 2018

J Biomedical Materials Res

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In this study, chitosan/bioactive glass (BG)/lawsone coatings were deposited by electrophoretic deposition (EPD) on polyetheretherketone (PEEK)/BG layers (previously deposited by EPD on 316-L stainless steel) to produce bioactive and antibacterial coatings. First, the EPD of chitosan/BG/lawsone was optimized on stainless steel in terms of suspension stability, homogeneity and thickness of coatings. Subsequently, the optimized EPD parameters were used to produce bioresorbable chitosan/bioactive glass (BG)/lawsone coatings on PEEK/BG layers. The produced layered coatings were characterized in terms of composition, microstructure, corrosion resistance, in vitro bioactivity, drug release kinetics and antibacterial activity. Ultraviolet/Visible (UV/VIS) spectroscopic analyses confirmed the release of lawsone from the coatings. Moreover, the deposition of chitosan/BG coatings was confirmed by Scanning Electron Microscopy (SEM) and Fourier Transform Infrared spectroscopy (FTIR). The coated specimens presented higher corrosion resistance (10 times) in comparison to that of bare 316-L stainless steel and showed convenient wettability for initial protein attachment. The presence of lawsone in the top layer provided antibacterial effects against Staphylococcus carnosus. Moreover, the developed coatings formed apatite-like crystals upon immersion in simulated body fluid, indicating the possibility of achieving close interaction between the coating surface and bone. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 3111-3122, 2018.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Electrophoretic deposition of lawsone loaded bioactive glass (BG)/chitosan composite on polyetheretherketone (PEEK)/BG layers as antibacterial and bioactive coating

Rehman

Baştan

Nawaz

et al. 2018

J Biomedical Materials Res

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“…The anticorrosive property was due to the pore sealing as well as the barrier effect of CS coating . Among CS/bioactive glass/SiO‐coated stainless steel and WE43 Mg alloys, the coated Mg alloy exhibited reduced corrosion, increased hardness as well as better adhesion when compared to the same coating on stainless steel . A number of reports are available indicating the use of CS as a surface modifier along with other materials in BTE applications ( Table ).…”

Section: Cs As a Surface Modifier In Btementioning

confidence: 99%

Chitosan in Surface Modification for Bone Tissue Engineering Applications

Abinaya

Prasith

Ashwin

et al. 2019

Biotechnology Journal

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Traditional methods of bone defect repair include autografts, allografts, surgical reconstruction, and metal implants that have several disadvantages such as donor site morbidity, rejection, risk of disease transmission, and repetitive surgery. Biomaterial‐based bone reconstructions can, therefore, be an efficient alternative due to the inherent properties of the materials. Chitosan (CS), the deacetylated form of chitin, is a biopolymer having a wide array of applicability in regenerative tissue applications owing to its biocompatible, in vitro degradative and bioresorbable nature. Extensive studies are being carried out using CS to augment the properties of the already existing methods and to also improve the applicability of CS‐based biocomposites in bone tissue repair. In this review, the suitability of CS as a surface modifier has been discussed in detail for the already existing implants, surface modifications of CS‐based natural biocomposites for bone tissue regeneration, and the wide range of techniques that can introduce these modifications. CS, being a natural polymer, possesses advantageous properties including surface modifier that makes it a suitable candidate for bone regeneration, and further research to investigate its osteogenic potential in vivo along with the molecular and signaling mechanisms involved in bone regeneration can aid in expanding its applicability in clinical trials.

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“…Furthermore, according to Heise et al [48], rough surfaces tend to promote increased nucleation and formation of apatite (aHA) when immersed in SBF, for instance, the Ti6Al4V/TM/ TM HA/AC (51%) and Ti6Al4V/TM/TM HA/PH (38%) samples, when compared to the Ti6Al4V/TM/TM HA/OE (35%) and Ti6Al4V/TM/TM HA (25%) samples after 672 hours of immersion. In addition, the higher wettability presented by Ti6Al4V/TM/TM HA/AC may also have influenced the hydrolytic degradation of this coating, thus contributing to its superior bioactive behavior in comparison with other samples [33,49].…”

Section: Bioactivitymentioning

confidence: 99%

Effect of Sterilization on the Properties of a Bioactive Hybrid Coating Containing Hydroxyapatite

Baldin

Malfatti

Rodói

et al. 2019

Advances in Materials Science and Engineering

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The objective of this study was to evaluate the influence of sterilization on a hybrid coating obtained from a sol composed of alkoxysilane tetraethoxysilane (TEOS) and organoalkoxysilane methyltriethoxysilane (MTES) containing 10% (mass) of hydroxyapatite particles. The coating was obtained by dip coating, by applying two layers (protective/bioactive), which were cured at different temperatures (450°C and 60°C). The effects of sterilization on the superficial, electrochemical, bioactive, and mechanical properties of the coating were evaluated by performing different sterilization processes, namely, steam autoclave, hydrogen peroxide plasma, and ethylene oxide. Subsequently, the coating was characterized by using scanning electron microscopy (SEM/FEG), and FTIR measurements were performed to characterize the chemical structure. The bioactivity and degradability of the coating were analyzed by mass variation after immersion in SBF and X-ray diffraction (XRD) analysis. The electrochemical behavior was assessed by open circuit potential (OCP) and potentiodynamic polarization curves and the mechanical behavior by wear resistance. Results showed that all sterilization processes caused significant morphological changes in the hybrid coating. The autoclaved sample presented the highest structural chemical changes, and, consequently, the highest degradability, even though it had a superior bioactive behavior in relation to the other samples. In addition, the sterilization processes influenced the electrochemical behavior of the hybrid coating and altered the mechanical resistance to abrasion, thus presenting lower wear performance in relation to the nonsterilized sample.

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Electrophoretic deposition of chitosan/bioactive glass/silica coatings on stainless steel and WE43 Mg alloy substrates

Cited by 63 publications

References 44 publications

Electrophoretic deposition of lawsone loaded bioactive glass (BG)/chitosan composite on polyetheretherketone (PEEK)/BG layers as antibacterial and bioactive coating

Electrophoretic deposition of lawsone loaded bioactive glass (BG)/chitosan composite on polyetheretherketone (PEEK)/BG layers as antibacterial and bioactive coating

Chitosan in Surface Modification for Bone Tissue Engineering Applications

Effect of Sterilization on the Properties of a Bioactive Hybrid Coating Containing Hydroxyapatite

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