“…Usually, the molecules collected from body fluid systems, cells, and tissues cultured in vitro can be still applied as accurate markers, making the detection process easier to operation and lower risk. Nowadays, numerous molecular biomarkers have been identified as targets for disease diagnosis, molecularly targeted therapy (Hood et al, 2004), biological research (Czapla and McPhail, 2015;Dimri et al, 1995), and even in environmental monitoring (Abdel-Halim et al, 2006;Marin and Matozzo, 2004). Bio-related molecules, such as nucleic acid, protein, lipid, and small ions which may participate in the bioprocess are the most prominent molecular biomarkers.…”