Electrophysiological and Behavioral Studies of the Optic Tectum in Cyclostomes

Karamian, A. I.; Vesselkin, Nicolai P.; Agayan, Armen L.

doi:10.1007/978-1-4899-5376-6_2

Cited by 4 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In lampreys and other non-mammalian vertebrates, the optic tectum is the main primary visual center of the brain, receiving extensive topographic retinal (retinotopic) projections to the superficial layers (Butler and Hodos, 1996 ; Iwahori et al, 1999 ; De Arriba and Pombal, 2007 ; Jones et al, 2009 ). Electroreceptive and other sensory input also converge onto this tectal map (Bodznick and Northcutt, 1981 ; Ronan and Northcutt, 1990 ; Robertson et al, 2006 ), where the relevance of salient stimuli can be assessed, as in other vertebrates (Karamian et al, 1966 , 1984 ; Pombal et al, 2001 ; Gruberg et al, 2006 ; Kardamakis et al, 2015 ), leading to orienting movements of the eye, head and trunk (Saitoh et al, 2007 ; Ocaña et al, 2015 ).…”

Section: Discussionmentioning

confidence: 99%

Ontogenetic shifts in brain scaling reflect behavioral changes in the life cycle of the pouched lamprey Geotria australis

et al. 2015

View full text Add to dashboard Cite

Very few studies have described brain scaling in vertebrates throughout ontogeny and none in lampreys, one of the two surviving groups of the early agnathan (jawless) stage in vertebrate evolution. The life cycle of anadromous parasitic lampreys comprises two divergent trophic phases, firstly filter-feeding as larvae in freshwater and secondly parasitism as adults in the sea, with the transition marked by a radical metamorphosis. We characterized the growth of the brain during the life cycle of the pouched lamprey Geotria australis, an anadromous parasitic lamprey, focusing on the scaling between brain and body during ontogeny and testing the hypothesis that the vast transitions in behavior and environment are reflected in differences in the scaling and relative size of the major brain subdivisions throughout life. The body and brain mass and the volume of six brain structures of G. australis, representing six points of the life cycle, were recorded, ranging from the early larval stage to the final stage of spawning and death. Brain mass does not increase linearly with body mass during the ontogeny of G. australis. During metamorphosis, brain mass increases markedly, even though the body mass does not increase, reflecting an overall growth of the brain, with particularly large increases in the volume of the optic tectum and other visual areas of the brain and, to a lesser extent, the olfactory bulbs. These results are consistent with the conclusions that ammocoetes rely predominantly on non-visual and chemosensory signals, while adults rely on both visual and olfactory cues.

show abstract

Section: Discussionmentioning

confidence: 99%

Ontogenetic shifts in brain scaling reflect behavioral changes in the life cycle of the pouched lamprey Geotria australis

et al. 2015

View full text Add to dashboard Cite

show abstract

“…In spite of their superficial resemblances, the hagfish and lampreys diverged early in vertebrate phylogeny, and lampreys are now considered to be more closely related to the Gnathostomes, or jawed vertebrates, than to the hagfish (Forey and Janvier 1993;Janvier 1996). In this light, authors are in general agreement that the central nervous system of the lamprey can be considered as the prototype of that of the Gnathostomes (Heier 1948;Nieuwenhuys 1977;Karamian et al 1984;Nieuwenhuys and Nicholson 1998;Robertson et al 2006Robertson et al , 2007. The numerous studies of the functional anatomical organisation of the primary visual system of the lamprey, carried out over several decades (Northcutt and Przybylski 1973;Kennedy and Rubinson 1977;Kosareva et al 1977;Rubinson and Kennedy 1979;Repérant et al 1980Repérant et al , 1990Kosareva 1980;Vesselkin et al 1980Vesselkin et al , 1996Karamian et al 1984;de Miguel et al 1990;Rubinson, 1990;Pierre et al 1992;Rio et al 1993) are in agreement with this hypothesis.…”

Section: Introductionmentioning

confidence: 89%

“…Ebbesson 1970Ebbesson , 1972Repérant et al 1990). The organisation of this projection in the lamprey has been studied by electrophysiological methods (Karamian et al 1984) and by a variety of hodological techniques at the level of resolution of the light microscope (Northcutt and Przybylski 1973;Kennedy and Rubinson 1977;Kosareva et al 1977;Kosareva 1980;Repérant et al 1980Repérant et al , 1990Vesselkin et al 1980Vesselkin et al , 1984Vesselkin et al , 1996de Miguel et al 1990;Rubinson 1990). While the synaptic circuitry of the retinorecipient layers of the optic tectum, or its mammalian equivalent, the superior colliculus, has been extensively studied in all major groups of Gnathostomes (for reviews: teleosts, Vanegas et al 1984;Peyrichoux et al 1986;Kageyama and Meyer 1989;amphibians, Lázár 1984;Antal 1991;Gábriel and Straznicky 1995;reptiles, Repérant et al 1997;Rio et al 1995;birds, Morino et al 1991;Tömböl 1998;Tömböl and Németh 1999;Tömböl et al 2003;mammals, Mize 1992;Mize and Butler 1995;Mize et al 1994;Ortega et al 1995) no comparable ultrastructural studies have been carried out in the lamprey, with the exception of a preliminary study by Rio et al (1996).…”

Section: Introductionmentioning

confidence: 99%

Synaptic circuitry in the retinorecipient layers of the optic tectum of the lamprey (Lampetra fluviatilis). A combined hodological, GABA and glutamate immunocytochemical study

et al. 2009

View full text Add to dashboard Cite

The ultrastructure of the retinorecipient layers of the lamprey optic tectum was analysed using tract tracing techniques combined with GABA and glutamate immunocytochemistry. Two types of neurons were identified; a population of large GABA-immunonegative cells, and a population of smaller, highly GABA-immunoreactive interneurons, some of whose dendrites contain synaptic vesicles (DCSV). Five types of axon terminals were identified and divided into two major categories. The first of these are GABA-immunonegative, highly glutamate-immunoreactive, contain round synaptic vesicles, make asymmetrical synaptic contacts, and can in turn be divided into AT1 and AT2 terminals. The AT1 terminals are those of the retinotectal projection. The origin of the nonretinal AT2 terminals could not be determined. AT1 and AT2 terminals establish synaptic contacts with DCSV, with dendrites of the retinopetal neurons (DRN), and with conventional dendritic (D) profiles. The terminals of the second category are GABA-immunoreactive and can similarly be divided into AT3 and AT4 terminals. The AT3 terminals contain pleiomorphic synaptic vesicles and make symmetrical synaptic contacts for the most part with glutamate-immunoreactive D profiles. The AT4 terminals contain rounded synaptic vesicles and make asymmetrical synaptic contacts with DRN, with DCSV, and with D profiles. A fifth, rarely observed category of terminals (AT5) contain both clear synaptic vesicles and a large number of dense-core vesicles. Synaptic triads involving AT1, AT2 or AT4 terminals are rare. Our findings are compared to these of previous studies of the fine structure and immunochemical properties of the retinorecipient layers of the optic tectum or superior colliculus of Gnathostomes.

show abstract

“…The optic tectum is the midbrain target of visual pathways in lampreys (Northcutt and Przybylski, ; Kennedy and Rubinson, ; Vesselkin et al, ; Karamian et al, ). In the sea lamprey, a large number of ASP‐ir tectal cells were observed mainly in radial cells of the inner tectal gray layers (stratum griseum periventriculare and, in a lower proportion, in the inner part of the stratum griseum centrale).…”

Section: Discussionmentioning

confidence: 99%

Aspartate‐containing neurons of the brainstem and rostral spinal cord of the sea lamprey Petromyzon marinus: Distribution and comparison with γ‐aminobutyric acid

Villar-Cerviño

Fernández-López

Rodicio

et al. 2014

J of Comparative Neurology

View full text Add to dashboard Cite

The amino acid L-aspartate (ASP) is one of the most abundant excitatory neurotransmitters in the mammalian brain, but its distribution in other vertebrates has not yet been well characterized. We investigated the distribution of ASP in the brainstem and rostral spinal cord of the adult sea lamprey by using ASP immunohistochemistry. Our results indicate that ASP is accumulated in specific neurons, but not in glia (tanycytes). ASP-immunoreactive neuronal populations were rather similar as the glutamatergic populations reported in the adult sea lamprey (Villar-Cerviño et al. [2013] J Comp Neurol 521:522-557), although some important differences were noted. Characteristically, the largest reticular neurons of the lamprey brainstem (Müller cells) showed ASP immunoreactivity in perikarya and processes, in contrast to the absence or faint glutamate immunoreactivity reported in these perikarya. We also compared the distribution of ASP and γ-aminobutyric acid (GABA) in brainstem neurons by using double immunofluorescence methods. In regions such as the midbrain tectum, dorsal isthmus, and motor nuclei, ASP and GABA immunoreactivity was mostly located in different neurons, whereas in other nuclei (torus semicircularis, octavolateralis area, parvocellular reticular formation), many of the ASP-immunonegative neurons displayed colocalization with GABA. These results, together with those of our previous studies of colocalization of glutamate and GABA, suggest that some lamprey neurons may co-release both excitatory and inhibitory neurotransmitters. Further investigation is needed to elucidate the pathways of uptake and release of ASP by ASP-immunoreactive neurons. Our results indicate that ASP is a neurotransmitter in the central nervous system representative of agnathans, the earliest vertebrate group.

show abstract

Electrophysiological and Behavioral Studies of the Optic Tectum in Cyclostomes

Cited by 4 publications

References 0 publications

Ontogenetic shifts in brain scaling reflect behavioral changes in the life cycle of the pouched lamprey Geotria australis

Ontogenetic shifts in brain scaling reflect behavioral changes in the life cycle of the pouched lamprey Geotria australis

Synaptic circuitry in the retinorecipient layers of the optic tectum of the lamprey (Lampetra fluviatilis). A combined hodological, GABA and glutamate immunocytochemical study

Aspartate‐containing neurons of the brainstem and rostral spinal cord of the sea lamprey Petromyzon marinus: Distribution and comparison with γ‐aminobutyric acid

Contact Info

Product

Resources

About