Electrophysiological assessments of cognition and sensory processing in TBI: Applications for diagnosis, prognosis and rehabilitation

Folmer, Robert L.; Billings, Curtis J.; Diedesch-Rouse, Anna C.; Gallun, Frederick J.; Lew, Henry L.

doi:10.1016/j.ijpsycho.2011.03.005

Cited by 54 publications

(36 citation statements)

References 90 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Auditory brainstem responses were not different between the two groups [60], suggesting that the differences were specifically related to central rather than peripheral effects of the blast. Electrophysiological measures in a range of sensory modalities have been shown to relate to outcomes after TBI (reviewed by Folmer et al [76]), but more research is needed before clear clinical guidelines for blast-exposed individuals can be developed.…”

Section: Discussionmentioning

confidence: 99%

Implications of blast exposure for central auditory function: A review

Gallun

Lewis

Folmer³

et al. 2012

JRRD

Self Cite

View full text Add to dashboard Cite

Abstract-Auditory system functions, from peripheral sensitivity to central processing capacities, are all at risk from a blast event. Accurate encoding of auditory patterns in time, frequency, and space are required for a clear understanding of speech and accurate localization of sound sources in environments with background noise, multiple sound sources, and/or reverberation. Further work is needed to refine the battery of clinical tests sensitive to the sorts of central auditory dysfunction observed in individuals with blast exposure. Treatment options include low-gain hearing aids, remote-microphone technology, and auditory-training regimens, but clinical evidence does not yet exist for recommending one or more of these options. As this population ages, the natural aging process and other potential brain injuries (such as stroke and blunt trauma) may combine with blast-related brain changes to produce a population for which the current clinical diagnostic and treatment tools may prove inadequate. It is important to maintain an updated understanding of the scope of the issues present in this population and to continue to identify those solutions that can provide measurable improvements in the lives of Veterans who have been exposed to high-intensity blasts during the course of their military service.

show abstract

Section: Discussionmentioning

confidence: 99%

Implications of blast exposure for central auditory function: A review

Gallun

Lewis

Folmer³

et al. 2012

JRRD

Self Cite

View full text Add to dashboard Cite

show abstract

“…Lew et al found that 62 percent of combat Veterans complained of hearing loss, while 38 percent reported tinnitus [7]. It is unknown whether hearing loss and tinnitus in these Veterans is a result of central auditory pathway disorder [28] or injury to the peripheral auditory system (e.g., cochlear). A number of studies have shown that blast exposure can result in damage to the hearing mechanism, but this is not consistently reflected as hearing loss in audiometric-threshold data, making evaluation of patients using a dual-sensory methodology worthwhile [29][30].…”

Section: Introductionmentioning

confidence: 99%

Development of a comprehensive Blast-Related Auditory Injury Database (BRAID)

Joseph¹,

Horton

Clouser

et al. 2016

J Rehabil Res Dev

View full text Add to dashboard Cite

Abstract-The Department of Defense Hearing ConservationProgram provides specific guidance for service components to prevent occupational hearing loss; however, it does not specifically contend with the unique noise exposures observed in the theater of war, such as blasts and explosions. In order to examine the effects of blast injury on hearing sensitivity, we developed a large database composed of demographic, audiometric, point of injury, and medical outcome data, with the primary aim of developing a long-standing and integrated capability for the surveillance, assessment, and investigation of blast-related hearing outcomes. Methods used to develop the dataset are described. Encompassing more than 16,500 Navy and Marine Corps personnel, the Blast-Related Auditory Injury Database (BRAID) includes individuals with a blast-related injury and nonblast control subjects. Using baseline and postdeployment hearing threshold data, a retrospective analysis of the cohort revealed that the rate of hearing loss for the injured servicemembers was 39%. The BRAID will be useful for studies that assess hearing patterns following deployment-related injury, such as blast exposures, that facilitate exploration of health outcomes and whether they are predictive of audiometric disposition and that help establish hearing loss prevention strategies and program policies for affected military commands and servicemembers.

show abstract

“…Unfortunately, it is difficult to tell the two effects apart. The CNV has approximately the same scalp distribution as the N400; it can be more prolonged in duration and has an onset latency varying between 260 and 470 msec (Folmer, Billings, Diedesch-Rouse, Gallun, & Lew, 2011). If the negativity disappears when no explicit judgment task is carried out, that would suggest that the explicit task contributes to the effect and that the reported negativity should be considered a CNV rather than an N400.…”

Section: Introductionmentioning

confidence: 99%

Less Is Not More: Neural Responses to Missing and Superfluous Accents in Context

Dimitrova

Stowe

Redeker

et al. 2012

Journal of Cognitive Neuroscience

View full text Add to dashboard Cite

Abstract■ Prosody, particularly accent, aids comprehension by drawing attention to important elements such as the information that answers a question. A study using ERP registration investigated how the brain deals with the interpretation of prosodic prominence. Sentences were embedded in short dialogues and contained accented elements that were congruous or incongruous with respect to a preceding question. In contrast to previous studies, no explicit prosodic judgment task was added. Robust effects of accentuation were evident in the form of an "accent positivity" (200-500 msec) for accented elements irrespective of their congruity. Our results show that incongruously accented elements, that is, superfluous accents, activate a specific set of neural systems that is inactive in case of incongruously unaccented elements, that is, missing accents. Superfluous accents triggered an early positivity around 100 msec poststimulus, followed by a right-lateralized negative effect (N400). This response suggests that redundant information is identified immediately and leads to the activation of a neural system that is associated with semantic processing (N400). No such effects were found when contextually expected accents were missing. In a later time window, both missing and superfluous accents triggered a late positivity on midline electrodes, presumably related to making sense of both kinds of mismatching stimuli. These results challenge previous findings of greater processing for missing accents and suggest that the natural processing of prosody involves a set of distinct, temporally organized neural systems. ■

show abstract

Electrophysiological assessments of cognition and sensory processing in TBI: Applications for diagnosis, prognosis and rehabilitation

Cited by 54 publications

References 90 publications

Implications of blast exposure for central auditory function: A review

Implications of blast exposure for central auditory function: A review

Development of a comprehensive Blast-Related Auditory Injury Database (BRAID)

Less Is Not More: Neural Responses to Missing and Superfluous Accents in Context

Contact Info

Product

Resources

About