Electrospinning an essential oil: Cinnamaldehyde enhances the antimicrobial efficacy of chitosan/poly(ethylene oxide) nanofibers

Rieger, Katrina A.; Schiffman, Jessica D.

doi:10.1016/j.carbpol.2014.06.075

Cited by 216 publications

(148 citation statements)

References 66 publications

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“…También, Rieger et al [16], demostraron que las nanofibras de quitosano/CA/PEO pueden servir como vehículos de suministro de Cinamaldehido (CA) que potencialmente erradican las infecciones causadas por pseudomonas. Song et al [17], prepararon una membrana electrohilada de quitosano/poli(óxido de etileno) (PEO) que contenía nanopartículas de plata como un vehículo de administración implantable para la liberación dual de iones de clorhexidina y plata.…”

Section: Introductionunclassified

Preparación y caracterización de membranas poliméricas electrohiladas de policaprolactona y quitosano para la liberación controlada de clorhidrato de tiamina / Preparation and Characterization of Electrospun Polymeric Membranes of Polycaprolactone and Chitosan for Controlled Release of Thiamine Chlorhydrate

Cepeda

2016

Cienc. En Desarro.

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ResumenActualmente existen importantes investigaciones sobre la preparación de membranas porosas bioabsorbibles que permiten la liberación controlada de fármacos y vitaminas. En este estudio se propuso preparar membranas porosas a partir de policaprolactona (PCL) y quitosano (CS) bajo la técnica de electrohilado aplicando diferentes parámetros con el fin de evaluar sus características internas y propiedades para una potencial aplicación como liberador del clorhidrato de tiamina (Vitamina B 1 ). Además se desarrolló el estudio de la cinética de liberación In vitro del clorhidrato de tiamina (TC) con las membranas preparadas. Se obtuvo una membrana polimérica a partir de una disolución de

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Section: Introductionunclassified

Preparación y caracterización de membranas poliméricas electrohiladas de policaprolactona y quitosano para la liberación controlada de clorhidrato de tiamina / Preparation and Characterization of Electrospun Polymeric Membranes of Polycaprolactone and Chitosan for Controlled Release of Thiamine Chlorhydrate

Cepeda

2016

Cienc. En Desarro.

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“…For centuries, plant-derived essential oils have been used to fight bacterial infections but due to their complex antimicrobial mechanisms, only a few researches had reported the development of these volatile extracts for wound dressing materials production [40]. Rieger and Schiffman [40] incorporated the cinnamaldehyde (CA) as a volatile essential oil in chitosan/PEO nanofiber mat.…”

Section: Introductionmentioning

confidence: 99%

New wound dressing polymeric nanofiber containing green tea extract prepared by electrospinning method

et al. 2015

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The effect of green tea extract as a natural and ecofriendly antibacterial additive on the healing effect of chitosan/ polyethylene oxide wound dressing nanofiber was investigated. Three different polymeric nanofiber composite including chitosan, chitosan/polyethylene oxide and chitosan/polyethylene oxide/green tea extract, was produced by electrospinning method and was used as wound dressing. Affecting parameters on electrospinning method such as voltage, feed rate, nozzlecollector distance and content of green tea in nanofiber structure were studied and optimized. The morphology of electrospun nanofibers was studied with use of scanning electron microscope. The average diameters of prepared nanofibers was determined by Image J software. The optimum conditions for preparation of electrospun nanofibers were: Voltage; 20 kV, feed rate; 0.5 ml/h, nozzle-collector distance; 10 cm, and chitosan/polyethylene oxide weight ratio; 0.9. Stability, water absorption and degradation of prepared nanofibers were investigated by placing the prepared nanofibers for 24 hours in a solution of acetate buffer with a pH of 5.5 and a temperature of 37 o C. Moreover, the antibacterial activity of composite scaffolds were tested by Agar plate method by two type bacteria including Escherichia coli and Staphylococcus aureus. Furthermore, the healing ability of the prepared nanofibers was studied on the rat's wound. Chitosan/polyethylene oxide/ green tea showed the best healing effects in comparison with the other prepared wound dressings. These results confirmed that green tea extract helps to keep wound surface moist, reduces inflammation and increases the speed of recovery and healing.

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“…Recently, composite chitosan fibres with enhanced antibacterial properties have been prepared using natural bioactive compounds, such as essential oils and honey. [97][98][99][100] Cinnamon oil has been incorporated into chitosan/poly(ethylene oxide) (PEO) fibres having a diameter of around 50 nm. 97 The electrospun mats were able to release the essential oil in vitro, and exhibited antibacterial activity against E. coli and P. aeruginosa.…”

Section: Chitosanmentioning

confidence: 99%

“…[97][98][99][100] Cinnamon oil has been incorporated into chitosan/poly(ethylene oxide) (PEO) fibres having a diameter of around 50 nm. 97 The electrospun mats were able to release the essential oil in vitro, and exhibited antibacterial activity against E. coli and P. aeruginosa. In another work, extracts of Garcinia mangostana (GM), a tropical fruit, were added to chitosan-ethylenediaminetetraacetic acid/polyvinyl alcohol (CS-EDTA/PVA) solutions and electrospun.…”

Section: Chitosanmentioning

confidence: 99%