Electrospinning for the manufacture of biosensor components: A mini‐review

Ahmed, Jubair

doi:10.1002/mds3.10136

Cited by 18 publications

(5 citation statements)

References 69 publications

(77 reference statements)

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“…as indicated by red arrows and circles. These particles correspond with the micrographs of the PG, meaning that some of the graphene has been dispersed onto the surface of the fibre, potentially advantageous as biosensor components and in producing antimicrobial surfaces [ 49 , 50 , 51 , 52 , 53 , 54 ].…”

Section: Resultsmentioning

confidence: 64%

Porous Graphene Composite Polymer Fibres

et al. 2020

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Since the isolation of graphene, there have been boundless pursuits to exploit the many superior properties that this material possesses; nearing the two-decade mark, progress has been made, but more is yet to be done for it to be truly exploited at a commercial scale. Porous graphene (PG) has recently been explored as a promising membrane material for polymer composite fibres. However, controlling the incorporation of high surface area PG into polymer fibres remain largely unexplored. Additionally, most polymer-graphene composites suffer from low production rates and yields. In this paper, graphene-loaded microfibres, which can be produced at a very high rate and yield have been formed with a carrier polymer, polycaprolactone. For the first time, PG has been incorporated into polymer matrices produced by a high-output manufacturing process and analysed via multiple techniques; scanning electron microscopy (SEM), Raman spectroscopy, Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). Raman spectra showed that single layer graphene structures were achieved, evidence for which was also backed up by the other techniques. Fibres with an average diameter ranging from 3–8 μm were produced with 3–5 wt% PG. Here, we show how PG can be easily processed into polymeric fibres, allowing for widespread use in electrical and ultrafiltration systems

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Section: Resultsmentioning

confidence: 64%

Porous Graphene Composite Polymer Fibres

et al. 2020

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“…Polymer nanofibers have enormous potential in areas such as wound healing [1][2][3], antibacterial dressings [4], biosensor devices [5,6], optoelectronics [7,8], and drug delivery systems [9,10]. Thus, nanofibers based on various polymers have attracted attention for application in the above-mentioned fields as a result of their remarkable properties, such as adjustable fiber diameter and porosity, tunable morphology, and the encapsulation capacity of the electrospun membrane.…”

Section: Introductionmentioning

confidence: 99%

Electrospun Polyvinyl Alcohol Loaded with Phytotherapeutic Agents for Wound Healing Applications

Serbezeanu¹,

Bargan²,

Homocianu³

et al. 2021

Nanomaterials

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In this paper, hydroalcoholic solutions of Thymus vulgaris, Salvia officinalis folium, and Hyperici herba were used in combination with poly (vinyl alcohol) with the aim of developing novel poly (vinyl alcohol)-based nanofiber mats loaded with phytotherapeutic agents via the electrospinning technique. The chemical structure and morphology of the polymeric nanofibers were investigated using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). The addition of Thymus vulgaris, Salvia officinalis folium, and Hyperici herba extracts to the pure polyvinyl alcohol fibers led to changes in the morphology of the fibers and a reduction in the fibers’ diameter, from 0.1798 µm in the case of pure polyvinyl alcohol to 0.1672, 0.1425, and 0.1369 µm in the case of polyvinyl alcohol loaded with Thymus vulgaris, Salvia officinalis folium, and Hyperici herba, respectively. The adapted Folin–Ciocalteu (FC) method, which was used to determine the total phenolic contents, revealed that the samples of PVA–Hyperici herba and PVA–Thymus vulgaris had the highest phenol contents, at 13.25 μgGAE/mL and 12.66 μgGAE/mL, respectively. Dynamic water vapor measurements were used in order to investigate the moisture sorption and desorption behavior of the developed electrospun materials. The antimicrobial behavior of these products was also evaluated. Disk diffusion assay studies with Escherichia coli, Staphylococcus aureus, and Methicillin-resistant Staphylococcus aureus were conducted on the developed nanofibers in order to quantify their phytotherapeutic potential.

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“…Because of the advantages in miniaturization, wearability, and real-time monitoring, biosensors have greatly promoted the development of efficient, accurate, and timely diagnostics in precision medicine [ 141 ]. Biosensors typically consist of a bioreceptor, a transducer, and a converter.…”

Section: Electrospinning For Precise Medicinementioning

confidence: 99%

Recent Advances in Electrospinning Techniques for Precise Medicine

Li,

Yin,

Zhou

et al. 2024

Cyborg Bionic Syst

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In the realm of precise medicine, the advancement of manufacturing technologies is vital for enhancing the capabilities of medical devices such as nano/microrobots, wearable/implantable biosensors, and organ-on-chip systems, which serve to accurately acquire and analyze patients’ physiopathological information and to perform patient-specific therapy. Electrospinning holds great promise in engineering materials and components for advanced medical devices, due to the demonstrated ability to advance the development of nanomaterial science. Nevertheless, challenges such as limited composition variety, uncontrollable fiber orientation, difficulties in incorporating fragile molecules and cells, and low production effectiveness hindered its further application. To overcome these challenges, advanced electrospinning techniques have been explored to manufacture functional composites, orchestrated structures, living constructs, and scale-up fabrication. This review delves into the recent advances of electrospinning techniques and underscores their potential in revolutionizing the field of precise medicine, upon introducing the fundamental information of conventional electrospinning techniques, as well as discussing the current challenges and future perspectives.

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Electrospinning for the manufacture of biosensor components: A mini‐review

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 18 publications

References 69 publications

Porous Graphene Composite Polymer Fibres

Porous Graphene Composite Polymer Fibres

Electrospun Polyvinyl Alcohol Loaded with Phytotherapeutic Agents for Wound Healing Applications

Recent Advances in Electrospinning Techniques for Precise Medicine

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