Electrospinning nanofiber scaffolds for soft and hard tissue regeneration

Xie, Xianrui; Chen, Yujie; Wang, Xiaoyu; Xu, Xiaoqing; Shen, Yulong; Khan, Atta Ur Rehman; Aldalbahi, Ali; Fetz, Allison E.; Bowlin, Gary L.; El‐Newehy, Mohamed H.; Mo, Xiumei

doi:10.1016/j.jmst.2020.04.037

Cited by 182 publications

(122 citation statements)

References 91 publications

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“…Larrondo and Manley proved in 1981 [23] that continuous filaments of rapidly crystallizing polymers could be spun from the melt using an electric field, and by 1996, Reneker and Chun studied the ability of some polymer solutions to be electrospun [24]. In the last years, a great quantity of scientific works on electrospinning have been recognized in the field of agriculture [25], filtration [26], tissue engineering [27] and packaging [28] among others.…”

Section: Electrospinning Technique and Post-processing Methodsmentioning

confidence: 99%

Potential Applications of Magnesium-Based Polymeric Nanocomposites Obtained by Electrospinning Technique

et al. 2020

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In the last few decades, the development of new electrospun materials with different morphologies and advanced multifunctional properties are strongly consolidated. There are several reviews that describe the processing, use and characterization of electrospun nanocomposites, however, based on our knowledge, no review on electrospun nanocomposites reinforced with nanoparticles (NPs) based on magnesium, Mg-based NPs, are reported. Therefore, in the present review, we focus attention on the fabrication of these promising electrospun materials and their potential applications. Firstly, the electrospinning technique and its main processing window-parameters are described, as well as some post-processing methods used to obtain Mg-based materials. Then, the applications of Mg-based electrospun nanocomposites in different fields are pointed out, thus taking into account the current trend in developing inorganic-organic nanocomposites to gradually satisfy the challenges that the industry generates. Mg-based electrospun nanocomposites are becoming an attractive field of research for environmental remediation (waste-water cleaning and air filtration) as well as for novel technical textiles. However, the mayor application of Mg-based electrospun materials is in the biomedical field, as pointed out. Therefore, this review aims to clarify the tendency in using electrospinning technique and Mg-based nanoparticles to huge development at industrial level in the near future.

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Section: Electrospinning Technique and Post-processing Methodsmentioning

confidence: 99%

Potential Applications of Magnesium-Based Polymeric Nanocomposites Obtained by Electrospinning Technique

et al. 2020

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“…Acknowledging the beneficial features, the electrospun nanofibers offers great possibility in the regeneration of various tissues in the human body as depicted in the Figure 7 [101]. Therefore, to date enormous progress have shown that the electrospun based scaffolds are greatly enhanced the repair/regeneration of different of tissues (e.g., bone, skin, nerve, heart, vascular and muscoskeletal system) due to its inherent properties of large surface area, porosity, stacking/pattering nature, alignment, mechanical strength, complex interface topology and easy functionalization nature [31,47,[102][103][104][105][106][107][108]. Therefore, we evidently discuss potential of electrospun nanofibers in the engineering of various tissues in the following sections.…”

Section: Electrospun Nanofibers In Tissue Engineering Applicationmentioning

confidence: 99%

“…Other tissue engineering and commercial prospectus Apart from the above tissue engineering applications, the electrospun nanofibers have been extensively explored for their potentials in other engineering other tissues including cardiac [137], skeletal muscle [138], tendon/ligament [139], blood vessel [107], dental [140], vascular [141], urethral [142] and cornea [143]. Based on the extensive discussion made throughout the article, it has been well evidenced that the electrospun nanofibers have been vastly used in the fabrication of scaffolds by adopting several approaches.…”

Section: Cartilage Tissue Engineeringmentioning

confidence: 99%

Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications

Balusamy

Anitha

Uyar

2020

Hacettepe Journal of Biology and Chemistry

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E lektro-eğirme yöntemi ile üretilen nanolifler, son yıllarda nanofibröz yapı iskelelerinin geliştirilmesinde büyük ilgi gördü ve biyomimetik yapıları nedeniyle farklı biyomedikal uygulamalarda kullanıldı. Özellikle, elektro-eğirme yöntemi ile üretilen nanolifler doğal hücre dışı matris (ECM), birbirine bağlı gözenekler, geniş yüzey alanı, işlevselleştirme kolaylığı ve hücre adezyonunu, farklılaşmasını ve proliferasyon davranışını etkilemede büyük önem taşıyan mekanik performans dahil olmak üzere birçok faydalı özellik sergiler. Bugüne kadar, çok çeşitli yararlı özellikleri kabul eden bu nanolifler, yara örtüsü ve doku mühendisliği uygulamalarında kullanılmıştır. Bu derlemede, çeşitli malzemelerin ve yaklaşımların kullanımını gösteren birkaç temsili örneklerle bu alanlarda çeşitli çabaların yapıldığını özetlemektedir. Ayrıca, klinik faz transferine ilişkin gelecekteki yön endişeleri tartışılmıştır. Anahtar Kelimeler Elektro-eğirme, nanolif, yara örtüsü, doku mühendisliği.

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“…The filter was made adopting the polyethylene terephthalate (PET) for the outer layer deposition and the polivinilidenfluoruro (PVDF) for the nanomembrane inner layer, developed via electrospinning [ 30 ] (dimensions 1460 × 2031 × 1435 mm). This latter technology offers a higher resolution and great advantages in material processing over a wide range of applications, such as biosensors [ 31 ], tissue engineering [ 32 , 33 ], drug delivery [ 34 ], and supercapacitors [ 35 ].…”

Section: Introductionmentioning

confidence: 99%

3D Printed Masks for Powders and Viruses Safety Protection Using Food Grade Polymers: Empirical Tests

Foresti

Ghezzi

Vettori³

et al. 2021

Polymers

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The production of 3D printed safety protection devices (SPD) requires particular attention to the material selection and to the evaluation of mechanical resistance, biological safety and surface roughness related to the accumulation of bacteria and viruses. We explored the possibility to adopt additive manufacturing technologies for the production of respirator masks, responding to the sudden demand of SPDs caused by the emergency scenario of the pandemic spread of SARS-COV-2. In this study, we developed different prototypes of masks, exclusively applying basic additive manufacturing technologies like fused deposition modeling (FDM) and droplet-based precision extrusion deposition (db-PED) to common food packaging materials. We analyzed the resulting mechanical characteristics, biological safety (cell adhesion and viability), surface roughness and resistance to dissolution, before and after the cleaning and disinfection phases. We showed that masks 3D printed with home-grade printing equipment have similar performances compared to the industrial-grade ones, and furthermore we obtained a perfect face fit by customizing their shape. Finally, we developed novel approaches to the additive manufacturing post-processing phases essential to assure human safety in the production of 3D printed custom medical devices.

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Electrospinning nanofiber scaffolds for soft and hard tissue regeneration

Cited by 182 publications

References 91 publications

Potential Applications of Magnesium-Based Polymeric Nanocomposites Obtained by Electrospinning Technique

Potential Applications of Magnesium-Based Polymeric Nanocomposites Obtained by Electrospinning Technique

Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications

3D Printed Masks for Powders and Viruses Safety Protection Using Food Grade Polymers: Empirical Tests

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