Electrospun antibacterial polyacrylonitrile nanofiber membranes functionalized with silver nanoparticles by a facile wetting method

Kharaghani, Davood; Jo, Young-Woo; Khan, Muhammad Qamar; Jeong, Yeonsu; Joon, Hyung; Kim, Ick Soo

doi:10.1016/j.eurpolymj.2018.08.021

Cited by 59 publications

(37 citation statements)

References 35 publications

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“…Gram-negative bacteria are more difficult to be killed than Gram-positive bacteria because they possess denser cell wall structures, which make them much less permeable to most antibacterial agents. Thus, many nanofibers incorporated with AgNPs were reported to show greater growthinhibiting efficacy against Gram-positive S. aureus than Gram-negative E. coli [47][48][49][50]. Nevertheless, clearer and larger diameter of the inhibition zone against E. coli (Gram-negative) was observed compared to S. aureus (Gram-positive) in this work, indicating that AgNPs-embedded FK/PVA/PEO composite nanofibers have better antibacterial activity against E. coli than S. aureus.…”

Section: Antibacterial Activitiesmentioning

confidence: 65%

Electrospun Silver Nanoparticles-Embedded Feather Keratin/Poly(vinyl alcohol)/Poly(ethylene oxide) Antibacterial Composite Nanofibers

Chen

Dou

et al. 2020

Polymers

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Feathers, which contain >90% keratin, are valuable natural protein resources. The aim of this study is to prepare antimicrobial feather keratin (FK)-based nanofibers by incorporating silver nanoparticles (AgNPs). A series of AgNPs-embedded feather keratin/poly(vinyl alcohol)/poly(ethylene oxide) (FK/PVA/PEO) composite nanofibers with varying amounts of AgNPs content were fabricated by electrospinning. Their morphology, crystallinity, thermal stability, tensile property, and antibacterial activity were systematically investigated. The average diameters of composite nanofibers gradually decreased with increases in the amount of AgNPs. The crystallinity, thermal stability, and antibacterial activity of FK/PVA/PEO nanofibers were enhanced by embedding AgNPs. When embedded with 1.2% AgNPs, both the tensile strength and elongation-at-break reached the highest level. This work has the potential to expand the application of FK-based nanofibers in the biomaterial field.

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Section: Antibacterial Activitiesmentioning

confidence: 65%

Electrospun Silver Nanoparticles-Embedded Feather Keratin/Poly(vinyl alcohol)/Poly(ethylene oxide) Antibacterial Composite Nanofibers

Chen

Dou

et al. 2020

Polymers

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“…Nanofibers are important part of biomedical technology, as 60% of the total nanofiber production is specifically used in biomedical applications, such as in tumor therapy, 7 wound dressing, drug delivery, self-healing of wounds, or implants. [8][9][10][11] Silver, incorporated with natural or synthetic polymers, has been used as an effective antibacterial agent since decades. Silver has potential applications in health care, especially in the form of nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

<p>Antibacterial properties of in situ and surface functionalized impregnation of silver sulfadiazine in polyacrylonitrile nanofiber mats</p>

Ullah¹,

Hashmi²,

Kharaghani³

et al. 2019

IJN

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Background: Silver, incorporation with natural or synthetic polymers, has been used as an effective antibacterial agent since decades. Silver has potential applications in healthcare especially in nanoparticles form but silver sulfadiazine (AgSD) is the most efficient antibacterial agent especially for burn wound dressings. Method: In this report, mechanical, structural, and antibacterial properties of PAN nanofibers incorporation with silver sulfadiazine are mainly focused. AgSD was loaded for the first time on electrospinning as well as self-synthesized AgSD on PAN nanofibers by solution immersion method and then compared the results of both. Results: Occurrence of chemical reaction among the functional groups of AgSD and PAN were analyzed using FTIR, for both types of specimen. Morphological and surface properties of prepared nanofiber mats were characterized by scanning electron microscope, and it resulted in uniform nanofibers without bead formation. Diameter of nanofibers was slightly increased with addition of AgSD by in situ and immersion methods respectively. Nanoparticles distribution was analyzed by transmission electron microscopy. Thermal properties were analyzed by thermogravimetric analyzer and it was observed that AgSD decreased thermal stability of PAN which is better from biomedical perspective. X-ray diffraction declared crystalline structure of nanofiber mats. Presence of Ag and S contents in nanofiber mats was analyzed by X-ray photo spectroscopy. Antibacterial properties of nanofiber mats were investigated by disc diffusion method was carried out. E. coli and Bacillus bacteria strain were used as gram-negative and gram-positive respectively. Zone inhibition of the bacteria was used as a tool to determine effectiveness of AgSD released from PAN nanofiber mats. The antibacterial properties of PAN nanofibers impregnated with AgSD were determined with both types of bacteria strains to compare with control one. Conclusion: On the basis of characterization results it is concluded that PAN/AgSD (immersion) nanofiber mats have better structural and antibacterial properties than that of PAN/AgSD (in situ) nanofiber mats. So, from our point of view, self-synthesized AgSD is recommended for further production of nanofiber mats for antibacterial applications.

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“…Polyacrylonitrile can also be easily physically modified, e.g., by functionalizing its surface or adding an additive to the PAN matrix. Nanofiber membranes for biomedical filtration devices were described by Kharaghani et al who received them of PAN functionalized with silver nanoparticles [7]. The nanofilters they presented had bactericidal effect against Escherichia coli and Staphylococcus aureus.…”

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confidence: 99%

The Influence of Graphene Addition on the Properties of Composite rGO/PAN Membranes and Their Potential Application for Water Disinfection

et al. 2020

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The paper presents a method of obtaining composite polyacrylonitrile-based (PAN) membranes with the addition of reduced graphene oxide (rGO). The membranes were obtained using phase inversion method from a homogeneous rGO dispersion in a solution of PAN dissolved in N, N-dimethylformamide (DMF). The impact of the amount of rGO addition to the PAN matrix on the physicochemical, structural, transport, and separation properties and on fouling resistance was studied. Composite membranes, due to the method of preparation used and the addition of rGO, are characterized by very good transport properties (~390 L/m2 h) and by a high degree of protein retention (85%). Reduced graphene oxide has biocidal properties, which, as we have shown, depend on the size of nanoparticles and the type of microorganism. rGO/PAN membranes, on the other hand, show biostatic properties against Gram-negative bacteria (Escherichia coli), Gram-positive bacteria (Staphylococcuc aureus) and fungi (Candida albicans). Thus, the obtained composite membranes can be potentially used in water disinfection.

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Electrospun antibacterial polyacrylonitrile nanofiber membranes functionalized with silver nanoparticles by a facile wetting method

Cited by 59 publications

References 35 publications

Electrospun Silver Nanoparticles-Embedded Feather Keratin/Poly(vinyl alcohol)/Poly(ethylene oxide) Antibacterial Composite Nanofibers

Electrospun Silver Nanoparticles-Embedded Feather Keratin/Poly(vinyl alcohol)/Poly(ethylene oxide) Antibacterial Composite Nanofibers

<p>Antibacterial properties of in situ and surface functionalized impregnation of silver sulfadiazine in polyacrylonitrile nanofiber mats</p>

The Influence of Graphene Addition on the Properties of Composite rGO/PAN Membranes and Their Potential Application for Water Disinfection

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