Electrospun antibacterial polyurethane–cellulose acetate–zein composite mats for wound dressing

Unnithan, Afeesh Rajan; Gnanasekaran, Gopalsamy; Sathishkumar, Yesupatham; Lee, Yang Soo; Kim, Cheol Sang

doi:10.1016/j.carbpol.2013.10.070

Cited by 302 publications

(154 citation statements)

References 20 publications

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“…For example, it was difficult for most of the natural polymers to be electrospun; however, addition of a synthetic polymer could improve the Electrospun Polyurethane Nanofibers http://dx.doi.org/10.5772/intechopen.69937processability of these polymers [82]. PUs are easy to electrospin and they can be mixed either with a natural polymer or with a synthetic polymer [83,84,87] for special applications such as collagen [88], dextran [43], and hydroxypropyl cellulose (HPC) [41].…”

Section: Electrospinning Of Pu/blends and Pu Nanocomposite Nanofibersmentioning

confidence: 99%

“…Similar behavior was observed for fibrinogen adsorption, which confirms that PU/HPC nanofibers are suitable in biomedical applications. Unnithan et al [87] combined PU with two biopolymers, cellulose acetate (CA) and zein to produce an antibacterial electrospun nanofibrous scaffolds. In another study, they used a solution composed of dextran, PU, and ciprofloxacin HCl (CipHCl) drug for wound dressing applications [43].…”

Section: Electrospinning Of Pu/blends and Pu Nanocomposite Nanofibersmentioning

confidence: 99%

“…Antibacterial and antimicrobial agents such as silver (Ag) nanoparticles [120], 4-vinylpyridine (4VP) [36], or streptomycin sulfate [87] loaded electrospun PU nanofibers were also developed for biomedical applications. Some of these studies combined the antibacterial properties of PU nanofibrous membranes with wound dressing applications.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

“…In the study of Unnithan et al [87], an antibacterial electrospun nanofibrous scaffolds with diameters around 400-700 nm were prepared by physically blending PU with two biopolymers, cellulose acetate (CA) and zein. They used PU as the foundation polymer, blended it with CA and zein to achieve better hydrophilicity, cell attachment, proliferation and blood clotting ability.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

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Electrospun Polyurethane Nanofibers

Akduman¹,

Kumbasar²

2017

Aspects of Polyurethanes

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The electrospinning process is highlighted with the ability of fabricating fibers with diameters on the nanometer scale, small inter-fibrous pore size and high porosity, vast possibilities for functionalization with high surface area to volume or mass ratio, ease of use and instrument setup, and adaptability. It attracted a great deal of attention due to its unique properties. More than 100 different polymers have been successfully electrospun into ultrafine fibers using this technique including synthetic polymers such as polyurethane (PU). Electrospun PU nanofiber mats exhibiting good mechanical properties may have a wide variety of potential applications in high-performance air filters, protective textiles, wound dressing materials, sensors, drug delivery, etc. This chapter deals with the electrospinning of polyurethane nanofibers and their potential applications.

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Section: Electrospinning Of Pu/blends and Pu Nanocomposite Nanofibersmentioning

confidence: 99%

Section: Electrospinning Of Pu/blends and Pu Nanocomposite Nanofibersmentioning

confidence: 99%

Section: Biomedical Applicationsmentioning

confidence: 99%

Section: Biomedical Applicationsmentioning

confidence: 99%

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Electrospun Polyurethane Nanofibers

Akduman¹,

Kumbasar²

2017

Aspects of Polyurethanes

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“…The ideal biomaterial for wound dressing must be possessing properties such as biocompatibility, gaseous exchange, flexibility, biodegradability, safeguard to prevent the bacterial infection and remove excess exudates [4,5]. Some of the commonly used polymers in medicine namely silicones, have been suspected to cause cancer and thus must be replaced by some biocompatible polymers [6].…”

Section: Introductionmentioning

confidence: 99%

Fabrication and Characterization of Electrospun PHA/Graphene Silver Nano-Composite Scaffold for Antibacterial Application

Mukheem¹,

Muthoosamy²,

Manickam³

et al. 2018

Preprint

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Many wounds are unresponsive to current available treatment techniques and therefore there is an immense need to explore suitable materials including biomaterials, which are being considered as the crucial factor to accelerate the healing cascade. In this study, we fabricated polyhydroxyalkanoate based antibacterial mats via electrospun technique. One-pot green synthesized graphene decorated silver nanoparticles (GAg) were incorporated into the fibres of poly-3 hydroxybutarate-co-12 mol% hydroxyhexanoate (P3HB-co-12mol% HHx), a co-polymer of polyhydroxyalkanoate (PHA) family which is highly biocompatible, biodegradable and flexible in nature. The synthesised PHA/GAg biomaterial was characterized by field emission scanning electron microscopy (FESEM), elemental mapping, thermogravimetric analysis (TGA), UV-visible spectroscopy (UV-vis) and Fourier transform infrared spectroscopy (FTIR). In-vitro antibacterial analysis were performed to investigate the efficacy of PHA/GAg against gram positive Staphylococcus aureus (S.aureus) strain 12600 ATCC and gram negative Escherichia coli (E.coli) strain 8739 ATCC. The results indicated that the PHA/GAg demonstrated significant reduction of Staphylococcus aureus (S.aureus strain 12600 ATCC) and Escherichia coli (E.coli strain 8739 ATCC) as compared to bare PHA or PHA-rGO in 2 hours of time. The P value (P< 0.05) was obtained by using 2 sample T-test distribution.

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Sonnenschein

2014

Polyurethanes

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Electrospun antibacterial polyurethane–cellulose acetate–zein composite mats for wound dressing

Cited by 302 publications

References 20 publications

Electrospun Polyurethane Nanofibers

Electrospun Polyurethane Nanofibers

Fabrication and Characterization of Electrospun PHA/Graphene Silver Nano-Composite Scaffold for Antibacterial Application

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