Electrospun nitrocellulose membrane for immunochromatographic test strip with high sensitivity

Wang, Xue; Yang, Dong; She, Jia; Zhao, Lingling; Jia, Tongtong; Xue, Chao-Hua

doi:10.1007/s00604-020-04626-8

Cited by 11 publications

(7 citation statements)

References 41 publications

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“…Several types of molecules can be used to detect SARS-CoV-2. The antigenic test procedure consists of depositing a nasopharyngeal swab dipped in a reactive fluid onto a nitrocellulose membrane [46]. The is added to a starting zone containing a conjugate detection reagent, which consists of a specific antibody to one of the epitopes of the antigen to be detected and a detection reagent [47].…”

Section: Use Of Colloidal Gold During the Covid-19 Pandemicmentioning

confidence: 99%

Perspective Chapter: Gold Nanoparticles Market – A Global Overview and New Challenges in the Post-Pandemic Economy

Verny¹,

Oulmakki²,

Meza³

2023

Gold Nanoparticles and Their Applications in Engineering

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Colloidal gold (AuNP) is a molecule obtained from pure gold (Au), and has several uses in the health, industrial, and chemical sectors. There are several processes to generate it and these methods are perfected over time. However, colloidal gold manufacturers and their customers are dependent on the pure gold market, its disruptions, and fluctuations. This paper first shows that the gold market is currently unstable due to the existing pandemic and geopolitical conflicts. The main gold producers, China, Russia, and Australia, together account for more than a quarter of the world’s gold production, and only a few European countries produce gold in small quantities. Europe is therefore forced to import gold, including colloidal gold. Several innovations related to gold nanoparticles are emerging, notably in the miniaturization of industrial components or in the health sector during the pandemic. The objective of this chapter is therefore to understand the patterns into which these countries must fit to produce these particles and the economic, political, and scientific stakeholders involved in capturing these flows. Through the prism of the gold market, the electronics industry, and the health field, this chapter looks at these issues while putting into perspective the salient facts that could impact this market in the years to come.

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Section: Use Of Colloidal Gold During the Covid-19 Pandemicmentioning

confidence: 99%

Perspective Chapter: Gold Nanoparticles Market – A Global Overview and New Challenges in the Post-Pandemic Economy

Verny¹,

Oulmakki²,

Meza³

2023

Gold Nanoparticles and Their Applications in Engineering

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“…[69][70][71] Second, they can be used in macroscopic flow-through systems. [72][73][74][75] Finally, EMs can be used as parts of LFA [76][77][78][79][80][81] or microfluidic devices. [82][83][84][85][86][87] The fundamental difference between these two options is the mechanism of liquid movement.…”

Section: Integration Of Electrospun Membranes Into Sensorsmentioning

confidence: 99%

“…Plenty of immobilization techniques have been described for this purpose, and many of them are applicable for electrospun NFs. 131 Although bare polymers are sometimes used as the substrate for the receptor layer, 77,79,87 surface treatment is usually applied to enhance the adsorption capacity, biosensor sensitivity, shelflife, and other properties. Various types of surface treatment have been described extensively, [132][133][134][135] so we will overview only those relevant to OSBEMs.…”

Section: Immobilization Of the Receptor Layer On The Membrane Surfacementioning

confidence: 99%

Optical sensors based on electrospun membranes – principles, applications, and prospects for chemistry and biology

et al. 2022

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“…Several technologies have been developed to prepare NC membranes, including phase inversion (Khamis et al 2020 ), electrospinning (Wang et al 2020 ), and spin coating (Horstmann et al 2020 ). Phase conversion technology requires complex post-treatment operation after casting nitrocellulose solution onto glass plates to NC membrane with high porosity and tunable pore size, requiring 17 h (Ahmad et al 2008 ; Khamis et al 2020 ; Tang et al 2019b ).…”

Section: Introductionmentioning

confidence: 99%

“…Phase conversion technology requires complex post-treatment operation after casting nitrocellulose solution onto glass plates to NC membrane with high porosity and tunable pore size, requiring 17 h (Ahmad et al 2008 ; Khamis et al 2020 ; Tang et al 2019b ). Electrospinning technology relying on a strong electric field is limited by relatively poor yields and costs of equipment, needing 36 h (B. Naderizadeh et al 2012 ; Luo et al 2012 ; Wang et al 2020 ). Spin coating technology utilizes centrifugal forces to disperse polymer solution on a flat polyester film substratum to reproducibly prepare NC membranes of uniform structure, requiring 13.5 h (Wang et al 2022b ; Yin et al 2010 ).…”

Section: Introductionmentioning

confidence: 99%

A nitrocellulose/cotton fiber hybrid composite membrane for paper-based biosensor

et al. 2023

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Nitrocellulose (NC) membrane was fabricated and tested for its potential use in various paper-based biosensors for use in point-of-care testing. However, contemporary technologies are complex, expensive, non-scalable, limited by conditions, and beset with potentially adverse effects on the environment. Herein, we proposed a simple, cost-effective, scalable technology to prepare nitrocellulose/cotton fiber (NC/CF) composite membranes. The NC/CF composite membranes with a diameter of 20 cm were fabricated in 15 min using papermaking technology, which contributes to scalability in the large-scale production of these composites. Compared with existing commercial NC membranes, the NC/CF composite membrane is characterized by small pore size (3.59 ± 0.19 μm), low flow rate (156 ± 55 s/40 mm), high dry strength (up to 4.04 MPa), and wet strength (up to 0.13 MPa), adjustable hydrophilic-hydrophobic (contact angles ranged from 29 ± 4.6 to 82.8 ± 2.4°), the good adsorption capacity of protein (up to 91.92 ± 0.07 μg). After lateral flow assays (LFAs) detection, the limit of detection is 1 nM, which is similar to commercial NC membrane (Sartorius CN 140). We envision the NC/CF composite membrane as a promising material for paper-based biosensors of point-of-care testing applications.

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Electrospun nitrocellulose membrane for immunochromatographic test strip with high sensitivity

Cited by 11 publications

References 41 publications

Perspective Chapter: Gold Nanoparticles Market – A Global Overview and New Challenges in the Post-Pandemic Economy

Perspective Chapter: Gold Nanoparticles Market – A Global Overview and New Challenges in the Post-Pandemic Economy

Optical sensors based on electrospun membranes – principles, applications, and prospects for chemistry and biology

A nitrocellulose/cotton fiber hybrid composite membrane for paper-based biosensor

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