Electrostatic Force and Centrifugal Force for Fiber Fabrication

Norzain, Norul Ashikin; Lin, Wei

doi:10.1109/icecos47637.2019.8984455

Cited by 7 publications

(5 citation statements)

References 10 publications

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“…For example, by increasing the applied voltage from 5 kV to 15 kV, the diameter PCL-PDMS fibre decrease from 759 ± 250 nm, 658 ± 310 nm, and 650 ± 228 nm, respectively. Also, the diameter of fibre showed a decreasing trend as the rotational speed increase from 1400 rpm to 2300 rpm which is 806 ± 346 nm, 759 ± 250 nm, and 600 ± 236 nm, respectively [15]. The optimum parameter could be applied not only to presume the diameter of the fibres, but morphology of fibres including beads, fibre-beads, and continuous fibres in the CES process.…”

Section: Resultsmentioning

confidence: 99%

“…The distance between the motor and the positive electrode of the high voltage supply is 200 mm. This design aims to prevent the CES machine from experiencing a breakdown of voltage during the process of fibre formation [15]. The circular collector was positioned around the spinneret.…”

Section: Fabrication Systemmentioning

confidence: 99%

“…This system is capable of reducing the safety concerns in which researchers utilised a centrifugal force from rotating motor, known as centrifugal spinning (CS) [11][12][13]. Centrifugal spinning can form micro/nanoscale fibres in aligned oriented at high rotational speed from 5000 to 12000 rpm [14], but the electrospun fibres are formed in non-uniformity and distributed in a ring form between the spinneret and circular collector [15,16].…”

Section: Introductionmentioning

confidence: 99%

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Orientated and diameter-controlled fibrous scaffolds fabricated using the centrifugal electrospinning technique for stimulating the behaviours of fibroblast cells

Norzain

Lin

2021

Journal of Industrial Textiles

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Centrifugal electrospinning (CES) was developed by integrating the electrospinning (ES) and centrifugal spinning (CS) concepts to produce oriented and diameter-controlled fibrous scaffolds which were then applied to stimulate the behaviour of fibroblast cells. During the fabrication process, polymer concentrations, rotational speeds, operating voltages, and needle sizes were key parameters to affect the diameters of produced fibres. The mathematical model indicated that the centrifugal force with the power of 2 was the main influence in fabricating thinner fibres, followed by electrostatic force with the power of 1. The developed CES technique could fabricate fibres scaffold ranging from 210 ± 50 nm to 2814 ± 96 nm by only applying low operating voltages and rotation speed which were 10 kV and up to 2000 rpm, respectively. Through optimum parameter, random and aligned nanofibrous were fabricated with the diameter being distributed mainly at 200–400 nm. Aligned nanofibrous demonstrated a high degree of orientation when 88% of the nanofibrous varied at 0°–10°. Compared to random structure, aligned nanofibrous presented high tensile strength, which was approximately 4.35 MPa and appropriate flexibility with 73% of elongation break. Aligned nanofibrous exhibited high cell viabilities with a 2.34 absorbance rate at day 14. The fibroblast cells elongated and accelerated in the orientation of the aligned nanofibrous. Results suggest that fibre aligned scaffolds are possible candidates for wound dressing application.

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Section: Resultsmentioning

confidence: 99%

Section: Fabrication Systemmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Orientated and diameter-controlled fibrous scaffolds fabricated using the centrifugal electrospinning technique for stimulating the behaviours of fibroblast cells

Norzain

Lin

2021

Journal of Industrial Textiles

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“…These physical and morphological properties could reduce the effect of cell behavior since the cell activities could be decreased with a minimal difference in the fiber diameters [ 37 , 38 , 39 , 40 ]. Hence, we assumed a structural scaffold can be fabricated by modified electrospinning [ 3 , 36 , 41 , 42 , 43 , 44 ] in further studies, which is able to produce fibers with a more uniform distribution. This can lead to provide more positive effects on cell behavior.…”

Section: Resultsmentioning

confidence: 99%

Micropatterned Fibrous Scaffold Produced by Using Template-Assisted Electrospinning Technique for Wound Healing Application

Norzain

Lin

et al. 2021

Polymers

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This paper describes the fabrication of a structural scaffold consisting of both randomly oriented nanofibers and triangular prism patterns on the scaffold surface using a combination technique of electrospinning and collector templates. The polycaprolactone (PCL) nanofibers were electrospun over a triangular prism pattern mold, which acted as a template. The deposited scaffold was removed from the template to produce a standalone structural scaffold of three-dimensional micropatterned nanofibers. The fabricated structural scaffold was compared with flat randomly oriented nanofibers based on in vitro and in vivo studies. The in vitro study indicated that the structural scaffold demonstrated higher fibroblast cell proliferation, cell elongation with a 13.48 ± 2.73 aspect ratio and 70% fibroblast cell orientation compared with flat random nanofibers. Among the treatment groups, the structural scaffold escalated the wound closure to 92.17% on day 14. Histological staining of the healed wound area demonstrated that the structural scaffold exhibited advanced epithelization of the epidermal layer accompanied by mild inflammation. The proliferated fibroblast cells and collagen fibers in the structural scaffold appeared denser and arranged more horizontally. These results determined the potential of micropatterned scaffolds for stimulating cell behavior and their application for wound healing.

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“…This driving force is exacerbated when an electric field is applied. Several papers have addressed this topic, and it seems to be the only area where there is a consensus—regardless of whether it is solution or melt electrospinning, gravity is so weak compared with the centrifugal force that its effects are negligible [ 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 ].…”

Section: State Of the Art—impact Of Apparatus Orientation In Electmentioning

confidence: 99%

Impact of Apparatus Orientation and Gravity in Electrospinning—A Review of Empirical Evidence

2020

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Electrospinning is a versatile fibre fabrication method with applications from textile to tissue engineering. Despite the appearance that the influencing parameters of electrospinning are fully understood, the effect of setup orientation has not been thoroughly investigated. With current burgeoning interest in modified and specialised electrospinning apparatus, it is timely to review the impact of this seldom-considered parameter. Apparatus configuration plays a major role in the morphology of the final product. The primary difference between spinning setups is the degree to which the electrical force and gravitational force contribute. Since gravity is much lower in magnitude when compared with the electrostatic force, it is thought to have no significant effect on the spinning process. But the shape of the Taylor cone, jet trajectory, fibre diameter, fibre diameter distribution, and overall spinning efficiency are all influenced by it. In this review paper, we discuss all these developments and more. Furthermore, because many research groups build their own electrospinning apparatus, it would be prudent to consider this aspect as particular orientations are more suitable for certain applications.

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Electrostatic Force and Centrifugal Force for Fiber Fabrication

Cited by 7 publications

References 10 publications

Orientated and diameter-controlled fibrous scaffolds fabricated using the centrifugal electrospinning technique for stimulating the behaviours of fibroblast cells

Orientated and diameter-controlled fibrous scaffolds fabricated using the centrifugal electrospinning technique for stimulating the behaviours of fibroblast cells

Micropatterned Fibrous Scaffold Produced by Using Template-Assisted Electrospinning Technique for Wound Healing Application

Impact of Apparatus Orientation and Gravity in Electrospinning—A Review of Empirical Evidence

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