Electrostatic wrapping of eupatorium-based botanical herbicide with chitosan derivatives for controlled release

Wei

Polymer Engineering & Sci

et al. 2022

Herein, interpenetrating network (IPN) hydrogels were successfully prepared for the first time through integrating two cross‐linking reactions in water in one pot, including amine‐anhydride reaction and subsequent photopolymerization. First, the polymer containing anhydride groups was prepared via free radical copolymerization of maleic anhydride and acrylamide. Second, the as‐prepared polymer was dissolved in water with polyacrylamine hydrochloride, N‐isopropylacrylamide, polyethylene glycol dimethacrylate, 2‐acrylamido‐2‐methylpropanesulfonic acid, and photoinitiator to obtain a homogeneous transparent solution. Third, the mixed solution was put in water bath of 50°C for 1 h to obtain the first network via the amine‐anhydride click reaction. Afterward, the second network was formed by photopolymerization. Finally, the swelling and drug release behavior of the hydrogels were studied with isoniazid as a model drug. The results show the IPN hydrogel possesses pH and temperature sensitivity and their controlled‐release behavior can be tuned via adjusting pH and temperature. In view of the advantages of amine‐anhydride reaction and photopolymerization, the strategy described here is of significance for the preparation of IPN hydrogel.

Section: Resultsmentioning

confidence: 99%

Fabrication and characterization of interpenetrating network hydrogels based on sequential amine‐anhydride reaction and photopolymerization in water

Wei

Polymer Engineering & Sci

et al. 2022

“…The release of pesticides is reduced by a low to high, and only when the concentration reaches a certain height can the harmful organisms be killed. The controlled release vehicle maintains the drug concentration in the environment as much as possible above the effective concentration [7,8,[18][19][20]22,26,30,35,40,43,46,50,52,57,[66][67][68]. Finally, it is necessary to consider the deposition efficiency of pesticides, measurement and transfer, and other problems in the application process [8,11,13,22,26,29,55].…”

Section: Discussionmentioning

confidence: 99%

“…The controlled release vehicle maintains the drug concentration in the environment as much as possible above the effective concentration [7,8,[18][19][20]22,26,30,35,40,43,46,50,52,57,[66][67][68]. Finally, it is necessary to consider the deposition efficiency of pesticides, measurement and transfer, and other problems in the application process [8,11,13,22,26,29,55]. In addition, because the characteristics of the polysaccharide material might not be sufficient to carry the corresponding original drug molecules, the development of In addition, because the characteristics of the polysaccharide material might not be sufficient to carry the corresponding original drug molecules, the development of polysaccharide derivatives could not only make up for this shortcoming, but also link the corre-sponding trigger groups, such as photolysis, enzymatic hydrolysis, redox responsive degradation, pH-controlled release [75], etc., so as to further develop a variety of intelligently controlled release carriers to achieve the targeted drug release and protection.…”

Section: Discussionmentioning

confidence: 99%

“…The amphiphilic chitosan derivative, N,N-dimethylhexadecylcarboxymethyl chitosan (DCMC), was used as a carrier for rotenone [13]. Hydroxyisopropyl chitosan (HPCTS, positively charged) and carboxymethyl chitosan (CMC, good water solubility) were successfully used as degradable water-soluble carriers of AIEAS to achieve its controlled release [22], and so on. Furthermore, a novel nanocomposite (cl-Ch-pMAc@ZnO/CdSQDs) was developed under microwave irradiation by preparing ZnO/CdS QDs on anionically functionalized chitosan.…”

Section: Null Null 5 May 2019mentioning

confidence: 99%

See 1 more Smart Citation

Research Progress of a Pesticide Polymer-Controlled Release System Based on Polysaccharides

Zhang

Yang

et al. 2023

Polymers

In recent years, with the development of the nanomaterials discipline, many new pesticide drug-carrying systems—such as pesticide nano-metal particles, nano-metal oxides, and other drug-carrying materials—had been developed and applied to pesticide formulations. Although these new drug-loading systems are relatively friendly to the environment, the direct exposure of many metal nanoparticles to the environment will inevitably lead to potential effects. In response to these problems, organic nanomaterials have been rapidly developed due to their high-quality biodegradation and biocompatibility. Most of these organic nanomaterials were mainly polysaccharide materials, such as chitosan, carboxymethyl chitosan, sodium alginate, β-cyclodextrin, cellulose, starch, guar gum, etc. Some of these materials could be used to carry inorganic materials to develop a temperature- or pH-sensitive pesticide drug delivery system. Herein, the pesticide drug-carrying system developed based on polysaccharide materials, such as chitosan, was referred to as the pesticide polymer drug-carrying system based on polysaccharide materials. This kind of drug-loading system could be used to protect the pesticide molecules from harsh environments, such as pH, light, temperature, etc., and was used to develop the function of a sustained release, targeted release of pesticides in the intestine of insects, and achieve the goal of precise application, reduction, and efficiency of pesticides. In this review, the recent progress in the field of polysaccharide-based polymer drug delivery systems for pesticides has been discussed, and suggestions for future development were proposed based on the current situation.

J of Applied Polymer Sci

“…Controlled release is an effective means to achieve targeted transport of substances. [1][2][3][4][5] A precisely targeted release can not only give full play to the role of the carrier, but also avoid pollution caused by improper release (such as the toxic and side effects of drugs 6,7 ). The methods to control the release can be to apply external stimuli (such as pH, temperature, light, electric field, magnetic field, etc.…”

Section: Introductionmentioning

confidence: 99%

Fabrication, encapsulation and controlled release of multilayer capsule based on thermosensitivity and host‐guest interaction

Wang,

Liu,

et al. 2024

As an efficient means of material carrying, multilayer capsules are widely used in medicine, agriculture, food safety and other fields. Here, we report a kind of temperature‐triggered multilayer capsule with chitosan‐sodium dodecyl benzene sulfonate (CS‐SDBS) as the shell and gelatin bead containing α‐cyclodextrin (α‐CD@gelatin) as the core. The α‐CD@gelatin/CS‐SDBS multilayer capsules can simultaneously encapsulate various substances, such as drugs, fluorescent materials, and nanoparticles. The encapsulated substances do not interfere with each other because they are located in different layers. Both the temperature‐sensitive property of gelatin and the host‐guest interaction between α‐CD and SDBS are utilized to achieve temperature‐controlled release of substances in the multilayer capsules. The release rate can be adjusted by the α‐CD amount in the gelatin beads. The controlled drug release and chemical detection of the multilayer capsules are studied with sodium salicylate, iodine, and purple cabbage pigment as the carriers. The results show that the α‐CD@gelatin/CS‐SDBS multilayer capsules have excellent capabilities of encapsulation and controlled release, which are beneficial for their application in the fields of substance encapsulation, drug‐controlled release, and chemical detection.