Elevated beta-thromboglobulin and mean platelet volume levels may show persistent platelet activation in systemic lupus erythematosus patients

Abstract

Elevated beta-thromboglobulin levels in systemic lupus erythematosus patients may be associated with platelet activation in the early stages of disease, whereas lower mean platelet volume levels in the same population may be due to the effects of hydroxychloroquine and the inactivity of SLE.

Echocardiography and 6-Minute Walk Test for Assessing Disease Progression in Systemic Lupus Erythematosus

“…In all patients who were in SLE remission, the CRP, leukocyte, and complement levels were normal. The authors suggested that hydroxychloroquine therapy contributed to the lower MPV values[29]. The lower MPV values obtained in the study group were probably associated with higher disease activity.…”