Elicitation and Use of Patients’ Preferences in the Treatment of Psoriasis: A Systematic Review

Abstract

There is a growing advocacy to incorporate patients' preferences in psoriasis treatment. The aim of this study was to critically review the scientific evidence regarding the elicitation and use of patients' preferences in psoriasis treatment. Published studies were systematically identified through PubMed, the Cochrane Library, the Web of Knowledge, and PsychINFO. Additional studies were identified by reviewing the reference lists of retrieved articles and through contact with experts in the field. Included studies involved the elicitation or use of patient preferences related to the treatment of psoriasis or psoriatic arthritis. Twenty-three studies were included in the review. The earliest articles were published in the 1980s. Patients' preferences were elicited for psoriasis treatment options, treatment attributes and for health state characteristics. Preferences were elicited from both patients and physicians. No study examined the use of patients' preferences in psoriasis treatment decision-making. The evidence demonstrates that patients' preferences relevant to psoriasis treatment are present and measurable. How-ever, the potential use of those preferences has largely been ignored.

Evaluation of psoriasis patients’ attitudes toward benefit–risk and therapeutic trade-offs in their choice of treatments

“…Unlike our study, neither study considered the previous treatment history of patients and how this might impact decision making. Schaarschmidt et al26 concluded that incorporating patients’ preferences into the prescribing decision may facilitate increased adherence and lead to better treatment outcomes, a view shared by Umar et al28 whose systemic review concluded that using patients’ preferences in decision making would likely improve both patient satisfaction and treatment outcomes.…”

Patient preference for biologic treatments of psoriasis in Japan

“…In addition to considering the different characteristics of the biologics, consultation time with physicians is often limited and this also hampers decision‐making for patients and physicians. Understanding patient preference improves the quality of care that physicians are able to provide because integrating patient preference into decision‐making may increase the patient's treatment adherence and the overall success of treatment . However, one study pointed out time pressures and difficulties in eliciting patient preference as challenges for physicians .…”

Evaluation of psoralen ethosomes for topical delivery in rats by using in vivo microdialysis

“…4 More and more dermatologists across the world have started to prescribe PUVA therapy, and for many patients, it has become the first-choice treatment for the effective control of psoriasis. 5,6 Treatment with psoralen may increase tyrosinase activity and promote melanin synthesis in normal melanocytes adjacent to the damaged cells. 7,8 The conventional formulations of psoralen, such as tinctures and ointments, have weak percutaneous permeability and poor deposition in the skin, which usually leads to frequent administration and may cause adverse reactions.…”