“…Side effects were self-reported by participants and both physical and psychological side effects from HT were reported in the included studies. The most commonly reported physical side effects were fatigue (26)(27)(28)(29)(30)(31)(32)(33), hot flashes (26,27,(29)(30)(31)(33)(34)(35)(36)(37), night sweats (29,31,33,34,37), musculoskeletal pain J o u r n a l P r e -p r o o f (25,26,37,38,27,29,(31)(32)(33)(34)(35)(36), weight gain (26)(27)(28)(29)32,33,37), alopecia (29,32,33,35,37), sexual dysfunctions including loss of sexual interest (27,29,…”